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| 1 | Current advances in using tolerogenic dendritic cells as a therapeutic alternative in the treatment of type 1 diabetes显示文摘Type 1 diabetes(T1D)is an autoimmune disease characterized by the destruction of insulin-producingβ-cells of the pancreatic islets by autoreactive T cells,leading to high blood glucose levels and severe long-term complications.The typical treatment indicated in T1D is exogenous insulin administration,which controls glucose levels;however,it does not stop the autoimmune process.Various strategies have been implemented aimed at stoppingβ-cell destruction,such as cellular therapy.Dendritic cells(DCs)as an alternative in cellular therapy have gained great interest for autoimmune disease therapy due to their plasticity to acquire immunoregulatory properties both in vivo and in vitro,performing functions such as anti-inflammatory cytokine secretion and suppression of autoreactive lymphocytes,which are dependent of their tolerogenic phenotype,displayed by features such as semimature phenotype,low surface expression of stimulatory molecules to prime T cells,as well as the elevated expression of inhibitory markers.DCs may be obtained and propagated easily in optimal amounts from peripheral blood or bone marrow precursors,such as monocytes or hematopoietic stem cells,respectively;therefore,various protocols have been established for tolerogenic(tol)DCs manufacturing for therapeutic research in the treatment of T1D.In this review,we address the current advances in the use of tolDCs for T1D therapy,encompassing protocols for their manufacturing,the data obtained from preclinical studies carried out,and the status of clinical research evaluating the safety,feasibility,and effectiveness of tolDCs. | William de Jesús Ríos-Ríos Sorely Adelina Sosa-Luis Honorio Torres-Aguilar | 2021 | World Journal of Diabetes2021，12，5： | 2 |
| 2 | Film condensation in presence of non-condensable gases over horizontal tubes with progressively increasing radius of curvature in the direction of gravity 显示文摘 | Sore S K Chakraborty S | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 3 | Infuences of spray and operating parameters on penetration of vaporizing fuei droplets in a gas tur- bine eombustor 显示文摘 | Sharma N Y K A D Sore S K | 2001 | Applied Thermal Engineering2001，21，： | 1 |
| 4 | Detection of metastasis in cervical lymph nodes: CT and MR criteria and differential diagnosis显示文摘 | Sore PM | 1992 | AJR1992，158，5： | 1 |
| 5 | Detection of metastasis in cervical lymph nodes: CT and MR erilefia and differential diagnosis显示文摘 | Sore PM | 1992 | A JR Am J Roentgenol1992，158，5： | 1 |
| 6 | Tumors of the parapharyngeal space: preoperative valuation, diagnosis and surgical approaches 显示文摘 | Sore P Biller H Lawson W | 1981 | Ann Otol Rhinol laryngol1981，90，80： | 1 |
| 7 | Revised 2003 con sen su s on diagnostic criteria and long-termhealth risks related to polycystic ovary syndrome (PCOS)显示文摘 | The Rotterdam ESHRE/ASRM spon sored PCOS consensus work shopgroup | 2004 | H urn Re-prod2004，19，1： | 1 |
| 8 | A quantitative study of peripheral blood stem cell contamination in diffuse large-cell non-Hodgkin's lymphoma:one-half of patients significantly morbilize malignant cell显示文摘 | Jacquy C Soree A Lambert F | 2000 | Br J Haematol2000，110，3： | 1 |
| 9 | In vitro hatched oncospheeres of Asian Taenia from Korean and Taiwan develop into cysticerci in the peritoneal cavity of females scid (severe combined immunodeficiency) mice显示文摘 | ITO A ITO M Sore KS et ol | 1993 | J Helminthology1993，7，3： | 1 |
| 10 | Studies on evalua- tion of the strength of the adhesive-bonded joint using the ultrasonic resonance method 显示文摘 | Bindal V N Saksena T K Sore J N | 1992 | Applied Acoustics1992，35，1： | 1 |
| 11 | Electrochemical Control of Solid Phase Micro- extraction Using Unique Conductcing Polymer Coated Fibers 显示文摘 | Gbatu Thomp sore P Ceylan O | 1999 | Anal Commun1999，，36： | 1 |
| 12 | The uniform approach to breast fine needle aspiration biopsy显示文摘 | Developed and approved at National Cancer Institude-Spon sored Conference | 1996 | Acta Cytol1996，40，： | 1 |
| 13 | A quantitative study of peripheral blood stem cell contamination in diffuse large-cell non-Hodgkin's lymphoma: One-half of patients significantly mobilize malignant cells 显示文摘 | Jacquy C Soree A Lambert F Bosly A Ferrant A Andre M Parma J Kentos A Martiat P | 2000 | Br J Haematol2000，110，3： | 1 |
| 14 | Cleaved c-FLIP mediates the antiviral effect of TNF-α against hepatitis B virus by dysregulating hepatocyte nuclear factors显示文摘 | Yong Kwang Park Eun-Sook Park Doo Hyun Kim Sung Hyun Ahn Seung Hwa Park Ah Ram Lee Soree Park Hong Seok Kang Ji-Hyun Lee Jong Man Kim Suk-Koo Lee Keo-Heun Lim Nathalie Isorce Shuping Tong Fabien Zoulim Kyun-Hwan Kim | 2015 | Journal of Hepatology2015，，： | 1 |
| 15 | Coefficient of dischrage and spray cone angle of a pressure nozzle with combined axial and tangential entry of power-law fluids 显示文摘 | Biswas G Sore S K | 1986 | Applied Scienti- fic Research1986，43，： | 1 |
| 16 | Central nodal necrosis and extracapsular neoplastic spread in cervical lymph nodes: MR Imaging versus CT 显示文摘 | Yousem DM Sore PM Hackney DB | 1992 | Radiology1992，182，3： | 1 |
| 17 | Numerical predictions on the influences of the air blast velocity, initial bed porosity and bed height on the shape and size of raceway zone in a blast turnace显示文摘 | Mondal S S Sore S K | 2005 | Journal of Physics D : Applied Pbysics2005，38，： | 1 |
| 18 | Head and Neck Volume two显示文摘 | Sore PM Curtin HD | 1992 | USA : Mosby Year Book1992，917，： | 1 |
| 19 | Classification and termi- nology of neck dissections 显示文摘 | Ferlito A Sore P M Rinaldo A | 2000 | ORL J Otorhinolaryngol Relat Spec2000，62，4： | 1 |
| 20 | Influence of implantation induced Ni- doping on struetural, optieal, and morphologieal proper- ties of nanoerystalline CdS thin films 显示文摘 | Chandramohan S Straehe T Sarangi S N Sathyamoor- thy R Sore T | 2010 | Materials Sei- enee and Engineering B-Advaneed Functional Solid-State Materials2010，171，13： | 1 |
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