|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of calreticulin is associated with infiltration of T-cells in stage ⅢB colon cancer显示文摘AIM: To investigate the correlation between expression of calreticulin and infiltration of lymphocytes in stage ⅢB colon cancer. METHODS: Sixty-eight pathologically-confirmed speci-mens were obtained from stage ⅢB (T3N1M0) colon cancer patients who underwent radical resection between January 1999 and May 2002 at the Cancer Center of Sun Yat-Sen University, Guangzhou, China. Immuno-histochemical analysis was performed to show infiltration of lymphocytes and expression of calreticulin in colon cancer. Association between calreticulin expression, infiltration of lymphocytes, and 5-year survival rate of patients was assessed. RESULTS: The expression level of calreticulin was lower in cancer nest than in its adjacent normal epithelium since 61.8% (42/68) of the samples were stained with calreticulin in colon cancer. The expression of calreticulin in colon cancer was associated with the infi ltration of CD45RO+ cells rather than with that of CD3+ cells. In addition, the stronger expression of calreticulin and the higher infiltration of CD3+ and CD45RO+ cells in colon cancer were associated with the higher 5-year survival rate of patients. CONCLUSION: Expression of calreticulin is associated with infiltration of T-cells, which implies that a low expression level of molecular marker may represent a new mechanism underlying immune escape in colon cancer. | Rui-Qing Peng, Ya Ding, Xing Zhang, Yi-Xin Zeng, Xiao- Shi Zhang, State Key Laboratory of Oncology in South China, Biotherapy Center, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Ying-Bo Chen, Zhi-Wei Zhou, State Key Laboratory of Oncology in South China, Department of Gastric and Pancreatic Oncology, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Rong Zhang, State Key Laboratory of Oncology in South China, Department of Endoscopy, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Xing-Juan Yu, Yi-Xin Zeng, State Key Laboratory of Oncology in South China, Department of Experimental Research, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China | 2010 | World Journal of Gastroenterology2010，16，19： | 16 |
| 2 | The influence of impurity on the critical thickness of the CeO_2 buffer layer for coated conductors显示文摘The lattice parameters, band structure, density of state and elastic constant of RE-doped CeO2 (RE=Sm, Gd, Dy), the buffer material for coated HTS conductors, are calculated using the plane-wave method with pseudopotentials based on the density functional theory (DFT) of first-principle. The rule and mechanism of the effect of rare earth impurity on the critical thickness of the CeO2 buffer layer are investigated. It is found that, in the range of the calculation, the changes of the lattice volume V and elastic constant E of CeO2 with the impurity are mainly determined by the increased electrons ne of the system. The relationship of the elastic constant E and increased electrons ne is established. It is indicated that the critical thickness of the CeO2 single buffer layer doped with Sm, Gd, and Dy may be enhanced by 22%, 43% and 33%, respectively. | PAN Min1, HUANG Zheng2, MA HuanFeng2, QIANG WeiRong2, WEI LianFu1, WANG Long2 & ZHAO Yong1,3 1 Key Laboratory of Magnetic Levitation Technologies and Maglev Trains (Ministry of Education of China), Superconductivity R&D Center (SRDC), Southwest Jiaotong University, Chengdu 610031, China 2 School of Physical Science and Technology, Southwest Jiaotong University, Chengdu 610031, China 3 Superconductivity Research Group, School of Materials Science and Engineering, University of New South Wale, Sydney, 2052 NSW, Australia | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，7： | 3 |
| 3 | Design of multiresponsive hydrogel particles and assemblies显示文摘 | HENDRICKSON G R SMITH M H SOUTH A B | 2010 | Advanced Functional Materials2010，20，11： | 1 |
| 4 | Modeling simultaneous saccharification and fermentation of lignocellulose to ethanol in batch and continuous reactors显示文摘 | South C R Hogestt D A L Lyna L R | 1995 | Enzyme and Microb Technol1995，17，9： | 1 |
| 5 | Reactivity of the HIV-1 nucleocapsid protein p7 zinc nger domains from the perspective of density-functional theory显示文摘 | SOUTH T BLAKE P SOWDER R | 1990 | Biochemistry1990，29，： | 1 |
| 6 | Modeling simultaneous saccharification and fermentation of lignocellulose to ethanol in batch and continuous reactors 显示文摘 | South C R Hogset D A L Lynd L R | 1995 | Enzyme and Microbial Technology1995，17，： | 1 |
| 7 | Modeling simultaneous saccharification and fermentation of lignocellulose to ethanol in batch and continuous reactors显示文摘 | South C R Hogestt D A L Lyan L R | 1995 | Enzyme Microb Technol1995，17，： | 1 |
| 8 | Modeling simultaneous saccharification and fermentation of lignocellulose to ethanol in batch and continuous reactors显示文摘 | South C R Hogsett D A L Lynd D L R | 1995 | Enzyme Micro-bial Technology1995，17，9： | 1 |
| 9 | 查看详情显示文摘 | Hendrickson G R Smith M H South A B | | 0，，11： | 1 |
| 10 | Modular and dynamic functionalization of polymeric scaffolds显示文摘 | South C R Burd C Weck M | 2007 | Acc Chem Res2007，40，： | 1 |
| 11 | Solid- phase synthesis of proline analogs via a three compo- nent 1,3-dipolar cycloa-ddition 显示文摘 | Hamper B C Dukesherer D R South M S | 1996 | Tetrabedron Let- tcrs1996，37，： | 1 |
| 12 | Catalogue of the marinebenthic macroalgae of the Fiji Islands, South Pacific 显示文摘 | SOUTH G R SKELTON P A 2003 | 2003 | AustSyst Bot2003，16，： | 1 |
| 13 | 2010 i2b2/VA challenge on concepts,assertions,and relations in clinical text显示文摘 | UZUNER O SOUTH B R SHEN S | | 0，，05： | 1 |
| 14 | Reduced expression of insulin-like growth factor-binding protein-3(IGFBP-3)in Squamous cell carcinoma complicating recessive dystrophic epidermolysis bullnsa显示文摘 | Mallipeddi R Wessagowit V South AP | 2004 | J Invest Dermatol2004，122，5： | 1 |
| 15 | 查看详情显示文摘 | Hendrickson G R Smith M H South A B | | 0，，24： | 1 |
| 16 | Modeling retail trade areas using higher-order,multicavity weighted Voronoi diagrams显示文摘 | South R | 1997 | Journal of Retailing1997，73，4： | 1 |
| 17 | Occurrence and use of Compsopogott coeruleus ( Rhodophyta: Compsopogonaceae) in Fiji, South Pacific 显示文摘 | SOUTH G R SKELTON P A | 2002 | New Zealand Journal of Marine and Freshwater Research2002，36，4： | 1 |
| 18 | Detailed Japan Sea paleoceanography during the last 25 kyr: constraints from AMS dating and δ18O of planktonic foraminifera显示文摘 | Gorbarenko S A and South J R | 2000 | Palaeogeography Palaeoclimatology Palaeoecology2000，156，： | 1 |
| 19 | Modeling simultaneous saccharification and fermentation of lignocel- lulose to ethanol in batch and continuous reactors显示文摘 | SOUTH C R HOGSETT D A L LYND L R | 1995 | En- zyme Microb Technol1995，17，9： | 1 |
| 20 | Detailed Japan Sea paleoceanography during the last 25 kyr: constraints from AMS dating and δ18O of planktonic foraminifera显示文摘 | Gorbarenko S A South J R | 2000 | Palaeogeography Palaeoclimatology Palaeoecology2000，156，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员