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| 1 | Pioneer of prostate cancer: past, present and the future of FOXA1显示文摘Prostate cancer is the most commonly diagnosed noncutaneous cancers in North American men.While androgen deprivation has remained as the cornerstone of prostate cancer treatment,resistance ensues leading to lethal disease.Forkhead box A1(FOXA1)encodes a pioneer factor that induces open chromatin conformation to allow the binding of other transcription factors.Through direct interactions with the Androgen Receptor(AR),FOXA1 helps to shape AR signaling that drives the growth and survival of normal prostate and prostate cancer cells.FOXA1 also possesses an AR-independent role of regulating epithelial-to-mesenchymal transition(EMT).In prostate cancer,mutations converge onto the coding sequence and c/s-regulatory elements(CREs)of FOXA1,leading to functional alterations.In addition,FOXA1 activity in prostate cancer can be modulated post-translationally through various mechanisms such as LSD1-mediated protein demethylation.In this review,we describe the latest discoveries related to the function and regulation of FOXA1 in prostate cancer,pointing to their relevance to guide future clinical interventions. | Mona Teng Stanley Zhou Changmeng Cai Mathieu Lupien Housheng Hansen He | 2021 | Protein & Cell2021，12，1： | 12 |
| 2 | Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus显示文摘 | Naru Zhang Rudragouda Channappanavar Cuiqing Ma Lili Wang Jian Tang Tania Garron Xinrong Tao Sumaiya Tasneem Lu Lu Chien-Te K Tseng Yusen Zhou Stanley Perlman Shibo Jiang Lanying Du | 2016 | Cellular & Molecular Immunology2016，13，2： | 12 |
| 3 | Analysis of the Arabidopsis Floral Proteome:Detection of over 2000 Proteins and Evidence for Posttranslational Modifications显示文摘The proteome of the Arabidopsis flower has not been extensively studied previously. Here, we report a proteomic analysis of the wild type Arabidopsis flower. Using both two-dimensional electrophoresis/mass spectrometry (2-DGE/MS) and multi-dimensional protein identification technology (MudPIT) approaches, we identified 2 446 proteins. Although a single experiment or analysis uncovered only a subset of the proteins we identified, a combination of multiple experiments and analyses facilitated the detection of a greater number of proteins. When proteins are grouped according to RNA expression levels revealed by microarray experiments, we found that proteins encoded by genes with relatively high levels of expression were detected with greater frequencies. On the other hand, at the level of the individual gene/protein, there was not a good correlation between protein spot intensity and microarray values. We also obtained strong evidence for post-translational modification from 2-DGE and MudPIT data. We detected proteins that are annotated to function in protein synthesis, folding, modification, and degradation, as well as the presence of regulatory proteins such as transcription factors and protein kinases. Finally, sequence and evolutionary analysis of genes for active methyl group metabolisms suggests that these genes are highly conserved. Our results allow the formulation of hypotheses regarding post-translational regulation of proteins in the flower, providing new understanding about Arabidopsis flower development and physiology. | Baomin Feng Lianchao Li Xiaofan Zhou Bruce Stanley Hong Ma | 2009 | Journal of Integrative Plant Biology2009，51，2： | 2 |
| 4 | The S-toR transition of corti- costeroid-binding globulin and the mechanism of hormone release 显示文摘 | Zhou A Wei Z Stanley PLD | 2008 | JMol Biol2008，380，1： | 1 |
| 5 | Myeloperoxidase-Generated Oxidants Modulate Left Ventricular Remodeling but Not Infarct Size After Myocardial Infarction显示文摘 | Nikolay Vasilyev Timothy Williams Marie-Luise Brennan Samuel Unzek Xiaorong Zhou Jay W. Heinecke Douglas R. Spitz Eric J. Topol Stanley L. Hazen Marc S. Penn | 2005 | Circulation2005，，18： | 1 |
| 6 | Isolation and characterization of genes from the marine microalga Pavlova salina encoding three front-end desaturases involved in docosahexaenoic acid biosynthesis显示文摘 | Xue-Rong Zhou Stanley S. Robert James R. Petrie Dion M.F. Frampton Maged P. Mansour Susan I. Blackburn Peter D. Nichols Allan G. Green Surinder P. Singh | 2007 | Phytochemistry2007，，6： | 1 |
| 7 | Generalizations of Principally Injective Rings显示文摘 | Stanley S Page Zhou Yiqiang | 1998 | J of AL1998，206，： | 1 |
| 8 | Statistical tests for power-law cross-correlated processes显示文摘 | Podobnik B Jiang Z Zhou W and Stanley H E | 2011 | Phys Rev E2011，，： | 1 |
| 9 | Quasi- dual Rings显示文摘 | STANLEY S PAGE YIQIANG ZHOU | 2000 | Communications in Algebra2000，28，1： | 1 |
| 10 | Heterologous production of GLA and SDA by expression of an Echium plantagineum A6- desaturase gene 显示文摘 | Xue - Rong Zhou Stanley Robert Surinder Singh | 2006 | Plant Science2006，170，： | 1 |
| 11 | Evidence of cardiovascular protection by moderate alcohol: Role of nitric oxide显示文摘 | Laila H. Abou-agag Nicholas K. Khoo Ralf Binsack C. Roger White Victor Darley-Usmar Hernan E. Grenett Francois M. Booyse Stanley B. Digerness Fen Zhou Dale A. Parks | 2005 | Free Radical Biology and Medicine2005，，4： | 1 |
| 12 | Generalizations of principally injective rings显示文摘 | STANLEY S P ZHOU Yi-qiang | 1998 | J Alegebra1998，206，： | 1 |
| 13 | Generalization of principally injective rings 显示文摘 | Stanley S P Zhou Y Q | 1998 | Journal of Mathematical Research and Exposition1998，206，2： | 1 |
| 14 | Generalizations of principally injective rings显示文摘 | Stanley S Page Zhou Yi-qiang | 1998 | J Algebra1998，206，2： | 1 |
| 15 | Recommendations for the classification and nomenclature of the DNA-β satellites of begomoviruses显示文摘 | R. W. Briddon J. K. Brown E. Moriones J. Stanley M. Zerbini X. Zhou C. M. Fauquet | 2008 | Archives of Virology2008，，4： | 1 |
| 16 | Assortativity decreases the robustness of interdependent networks显示文摘 | Zhou D Stanley H D'Agostino G | 2012 | Physical Review E2012，86，06： | 1 |
| 17 | Generalizations of principally injective rings显示文摘 | Stanley S P ZHOU Yi-qiang | 1998 | J of Algebra1998，206，： | 1 |
| 18 | Geminivirus strain demarcation and nomenclature显示文摘 | Fauquet C M Briddon R W Brown J K Moriones E Stanley J Zerbini M and Zhou X | | 0，，： | 1 |
| 19 | Percolation of partially interdependent scale-free networks 显示文摘 | Zhou D Gao J Stanley H E | 2013 | Physical Review E Statistical Nonlinear and Soft Matter Physics2013，87，05： | 1 |
| 20 | Generalizations of principally injective rings显示文摘 | STANLEY S P ZHOU Yiqiang | 1998 | Algebra1998，206，2： | 1 |
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