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| 1 | 人免疫球蛋白转基因小鼠自身免疫性重症肌无力模型的建立显示文摘 | 孟繁平 杨康鹃 李芳芳 孙昌元 金权鑫 M. Stassen M. de Baets | 2005 | 中华微生物学和免疫学杂志2005，25，2： | 7 |
| 2 | The IBI1 Receptor ofβ-Aminobutyric Acid Interacts with VOZ Transcription Factors to Regulate Abscisic Acid Signaling and Callose-Associated Defense显示文摘Extemal and internal signals can prime the plant immune system for a faster and/or stronger response to pathogen attack.β-aminobutyric acid(BABA)is an endogenous stress metabolite that induces broad-spectrum disease resistance in plants.BABA perception in Arabidopsis is mediated by the aspartyl tRNA synthetase IBI1,which activates priming of multiple immune responses,including callose-associated cell wall defenses that are under control by abscisic acid(ABA).However,the immediate signaling components after BABA perception by IBI1,as well as the regulatory role of ABA therein,remain unknown.Here,we have studied the early signaling events controlling IBI1-dependent BABA-induced resistance(BABAIR),using untargeted transcriptome and protein interaction analyses.Transcriptome analysis revealed that IBI1-dependent expression of BABA-IR against the biotrophic oomycete Hyaloperonospora arabidopsidis is associated with suppression of ABA-inducible abiotic stress genes.Protein interaction studies identified the VOZ1 and VOZ2 transcription factors(TFs)as IBI1-interacting partners,which are transcrip-tionally induced by ABA but suppress pathogen-induced expression of ABA-dependent genes.Furthermore,we show that VOZ TFs require nuclear localization for their contribution to BABA-IR by mediating augmented expression of callose-associated defense.Collectively,our study indicates that the IBI1-VOZ signaling module channels pathogen-induced ABA signaling toward cell wall defense while simultaneously suppressing abiotic stress-responsive genes. | Roland E.Schwarzenbacher Grace Wardell Joost Stassen Emily Guest Peijun Zhang Estrella Luna Jurriaan Ton | 2020 | Molecular Plant2020，13，10： | 4 |
| 3 | Identification and Functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood 显示文摘 | Jonulet H Schmitt E Stassen M | 2001 | J Exp Med2001，9，11： | 3 |
| 4 | Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study显示文摘 | K. W. A. G?ttgens P. T. J. Janssen J. Heemskerk F. M. H. Dielen J. L. M. Konsten T. Lettinga A. G. M. Hoofwijk H. J. Belgers L. P. S. Stassen S. O. Breukink | 2015 | International Journal of Colorectal Disease2015，，2： | 2 |
| 5 | 重症肌无力转基因小鼠模型的建立显示文摘[目的]建立人免疫球蛋白转基因小鼠实验性自身免疫性重症肌无力模型.[方法]用电鳐电器官分离纯化的乙酰胆碱受体免疫人免疫球蛋白转基因小鼠,以肌肉收缩力判定病情,以放射免疫测定法测定动物血清中抗乙酰胆碱受体抗体滴度及动物全身肌肉乙酰胆碱受体浓度.[结果]实验动物血清中抗乙酰胆碱受体抗体滴度为6~296nmol,全身肌肉乙酰胆碱受体损失率最高达65%,部分动物出现肌肉收缩无力表现.[结论]成功地建立了人免疫球蛋白转基因小鼠实验性自身免疫性重症肌无力模型. | 李红花 金桂花 孟繁平 李英信 李芳芳 孙昌元 金权鑫 Stassen M de Baets M | 2006 | 延边大学医学学报2006，29，2： | 2 |
| 6 | Construction and characterization of a single-chain antibody fragment derived from thymus of a patient with myasthenia gravis 显示文摘 | Meng F Stassen M H Schillberg S | 2002 | Autoimmunity2002，35，2： | 1 |
| 7 | Identification and functional characterization of human CD4^+ CD25^+ T cells with regulatory properties isolated from peripheral blood显示文摘 | Jonuleit H Schmitt E Stassen M | 2001 | J Exp Med2001，193，11： | 1 |
| 8 | Serological markers of persistent,trachomatis in women with tubal factor subfertility显示文摘 | Den Hartog JE Land JA Stassen FR | 2005 | Hum Reprod2005，20，4： | 1 |
| 9 | Nature of the spermatogenic arrest in Dazl -/-mice显示文摘 | SCHRANS - STASSEN B H SAUNDERS P T COOKE H J | 2001 | Biol Re- prod2001，65，3： | 1 |
| 10 | Mortality of patients with mood disorders:follow - up over 34-38 years显示文摘 | Angst F Stassen HH Clayton PJ | | 0，，2： | 1 |
| 11 | Case report:sublingual epidermoid cyst in an elderly patient显示文摘 | Anderson S Stassen LF | 2014 | J Ir Dent Assoc2014，60，2： | 1 |
| 12 | Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood显示文摘 | Jonuleit H Schmitt E Stassen M | 2001 | J Exp Med2001，193，： | 1 |
| 13 | Prolonged abdominal wall pain caused by transfascial sutures used in the laparoscopic repair of incisional hernia显示文摘 | J. Vermeulen I. Alwayn L. P. S. Stassen | 2003 | Surgical Endoscopy2003，，9： | 1 |
| 14 | Conditioning in the flotation of gold,uranium oxide,and pyrite显示文摘 | Stassen F | 1991 | Journal of the South African Institute of Mining and Metallurgy1991，91，5： | 1 |
| 15 | Mast cells as rapid innate sensors of cytomegalovirus by TLR3/TRIF signaling-dependent and -independent mechanisms显示文摘简明比喻, ‘免疫系统装载了 gun' ,被用来在能在需求上几乎立即被释放与侵略者作斗争的能分泌的小粒由于他们大量有势力支持 inflammatory 和抗菌剂调停人的存储描述桅杆房间(MC ) 的角色。在主人环境定位了边界并且与模式识别受体的一个军火库装备了, MC 被注定是渗透 endothelial 和上皮的表面的病原体的快速的天生的传感器。尽管在抗菌剂和 antiparasitic 防卫的 MC 的重要性长被欣赏了,他们在对病毒的感染发出报警的角色仅仅最近被注意了。 cytomegalovirus ( CMV )上的工作在鼠科的模型的感染在在 CMV 的天生、适应的有免疫力的监视之间的新奇串音轴作为播放器揭示了 MC 在 MC ,它与 MC degranulation 和 chemokine CCL5 的版本被联系的那感染,提高保护的 CD8 T 房间的招募到病毒复制的血管外的地点,明确地到肺 interstitium 和牙槽的上皮。这里,我们由响应主人感染为 MC 激活和作为结果的 degranulation 调查条件阐述了这些研究。令人惊讶地,数据揭示了 MC 激活的二个时间地并且机械学地不同的波浪:取决于 TLR3/TRIF 发信号并且由没包含 TLR3/TRIF 发信号的 MC 的直接感染推迟了激活的几乎立刻的间接激活。产出有选择地从 MC 发源的表示 eGFP 记者病毒的房间类型特定的 Cre 再结合识别了是的 MC 一在 vivo 新,生产鼠科的 CMV 感染的第一点击的目标房间。 | Marc Becker Niels AW Lemmermann Stefan Ebert Pamela Baars Angelique Renzaho Jurgen Podlech Michael Stassen Matthias J Reddehase | 2015 | Cellular & Molecular Immunology2015，12，2： | 1 |
| 16 | Identification and functional characterization of human CD4 ( + )CD25 ( + ) T cells with regulatory properties isolated from peripheral blood显示文摘 | Jonuleit H Schmitt E Stassen M | 2001 | J Exp Med2001，193，11： | 1 |
| 17 | Prospective randomized trial of the benefits of a stemocleidomastoid flap after superficial parotidectomy 显示文摘 | Kerawala CJ McAloney N Stassen LF | 2002 | Br J Oral Maxillofac Surg2002，40，6： | 1 |
| 18 | Identification and func- tional characterization of human CD4 ( + ) CD25 ( + ) T cells with regulatory properties isolated from peripheral blood 显示文摘 | Jonuleit H Schmitt E Stassen M | 2001 | J Exp Med2001，193，11： | 1 |
| 19 | In-vitro profile and ex-vivo antico- agulant activity of the direct thromhin inhibitor dabigatran and its orally ac- tive prodrug,dabigatranetexilate显示文摘 | Wienen W Stassen JM Priepke H | 2007 | Thromb Haemost2007，98，： | 1 |
| 20 | Adenovirus-mediated transfer of tissue type plasminogen activator augments thrombolysis in tissue type plasminogen activator deficient and plasminogen activator inhibitor overexpressingmice显示文摘 | Carmeliet P Stassen JM van Vlaenderen I | 1997 | Blood1997，90，4： | 1 |
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