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| 1 | Mesenteric ischemia:Pathogenesis and challengingdiagnostic and therapeutic modalities显示文摘Mesenteric ischemia(MI) is an uncommon medical condition with high mortality rates. ΜΙ includes inadequate blood supply, inflammatory injury and eventually necrosis of the bowel wall. The disease can be divided into acute and chronic MI(CMI), with the first being subdivided into four categories. Therefore, acute MI(AMI) can occur as a result of arterial embolism, arterial thrombosis, mesenteric venous thrombosis and nonocclusive causes. Bowel damage is in proportion to the mesenteric blood flow decrease and may vary from minimum lesions, due to reversible ischemia, to transmural injury, with subsequent necrosis and perforation. CMI is associated to diffuse atherosclerotic disease in more than 95% of cases, with all major mesenteric arteries presenting stenosis or occlusion. Because of a lack of specific signs or due to its sometime quiet presentation, this condition is frequently diagnosed only at an advanced stage. Computed tomography(CT) imaging and CT angiography contribute to differential diagnosis and management of AMI. Angiography is also the criterion standard for CMI, with mesenteric duplex ultrasonography and magnetic resonance angiography also being of great importance. Therapeutic approach of MI includes both medical and surgical treatment. Surgical procedures include restoration of the blood flow with arteriotomy, endarterectomy or anterograde bypass, while resection of necrotic bowel is always implemented. The aim of this review was to evaluate the results of surgical treatment for MI and to present the recent literature in order to provide an update on the current concepts of surgical management of the disease. Mesh words selected include MI, diagnostic approach and therapeutic management. | Aikaterini Mastoraki Sotiria Mastoraki Evgenia Tziava Stavroula Touloumi Nikolaos Krinos Nikolaos Danias Andreas Lazaris Nikolaos Arkadopoulos | 2016 | World Journal of Gastrointestinal Pathophysiology2016，7，1： | 23 |
| 2 | Type 2 diabetes is associated with a worse functional outcome of ischemic stroke显示文摘AIM: To assess whether ischemic stroke severity and outcome is more adverse in patients with type 2 diabetes mellitus(T2DM). METHODS: Consecutive patients hospitalized for acute ischemic stroke between September 2010 and June 2013 were studied prospectively(n = 482; 40.2% males, age 78.8 ± 6.7 years). T2 DM was defined as self-reported T2 DM or antidiabetic treatment. Stroke severity was evaluated with the National Institutes of Health Stroke Scale(NIHSS) score at admission. The outcome was assessed with the modified Rankin scale(m RS) score at discharge and with in-hospital mortality. Adverse outcome was defined as m RS score at discharge ≥ 2 or in-hospital death. The length of hospitalization was also recorded.RESULTS: T2 DM was present in 32.2% of the study population. Patients with T2 DM had a larger waist circumference, higher serum triglyceride and glucose levels and lower serum high-density lipoprotein cholesterol levels as well as higher prevalence of hypertension, coronary heart disease and congestive heart failure than patients without T2 DM. On the other hand, diabetic patients had lower low-density lipoprotein cholesterol levels and reported smaller consumption of alcohol than non-diabetic patients. At admission, the NIHSS score did not differ between patients with and without T2DM(8.7 ± 8.8 and 8.6 ± 9.2, respectively; P = NS). At discharge, the m RS score also did not differ between the two groups(2.7 ± 2.1 and 2.7 ± 2.2 in patients with and without T2 DM, respectively; P = NS). Rates of adverse outcome were also similar in patients with and without T2DM(62.3% and 58.5%, respectively; P = NS). However, when we adjusted for the differences between patients with T2 DM and those without T2 DM in cardiovascular risk factors, T2 DM was independently associated with adverse outcome [relative risk(RR) = 2.39; 95%CI: 1.21-4.72, P = 0.012]. Inhospital mortality rates did not differ between patients with T2 DM and those without T2DM(9.0% and 9.8%, respectively; P = NS). In multivariate analysis adjusting for the difference in cardiovascular risk factors between the two groups, T2 DM was again not associated with in-hospital death. CONCLUSION: T2 DM does not appear to affect ischemic stroke severity but is independently associated with a worse functional outcome at discharge. | Konstantinos Tziomalos Marianna Spanou Stella D Bouziana Maria Papadopoulou Vasilios Giampatzis Stavroula Kostaki Vasiliki Dourliou Maria Tsopozidi Christos Savopoulos Apostolos I Hatzitolios | 2014 | World Journal of Diabetes2014，5，6： | 15 |
| 3 | Is there a role for glucagon-like peptide-1 receptor agonists in the management of diabetic nephropathy?显示文摘Chronic kidney disease constitutes a major microvascular complication of diabetes mellitus.Accumulating data suggest that glucagon-like peptide-1 receptor agonists(GLP-1 RAs)might have a role in the management of diabetic kidney disease(DKD).GLP-1 RAs appear to reduce the incidence of persistent macro-albuminuria in patients with type 2 diabetes mellitus.This beneficial effect appears to be mediated not only by the glucose-lowering action of these agents but also on their blood pressure lowering,anti-inflammatory and antioxidant effects.On the other hand,GLP-1 RAs do not appear to affect the rate of decline of glomerular filtration rate.However,this might be due to the relatively short duration of the trials that evaluated their effects on DKD.Moreover,these trials were not designed nor powered to assess renal outcomes.Given than macrolbuminuria is a strong risk factor for the progression of DKD,it might be expected that GLP-1 RAs will prevent the deterioration in renal function in the long term.Nevertheless,this remains to be shown in appropriately designed randomized controlled trials in patients with DKD. | Stavroula Veneti Konstantinos Tziomalos | 2020 | World Journal of Diabetes2020，11，9： | 3 |
| 4 | Diagnosis and endoscopic treatment of esophago-bronchial fistula due to gastric heterotopy显示文摘Heterotopic gastric mucosa patches are congenital gastrointestinal abnormalities and have been reported to occur anywhere along the gastrointestinal tract from mouth to anus.Complications of heterotopic gastric mucosa include dysphagia,upper gastrointestinal bleeding,upper esophageal ring stricture,adenocarcinoma and fistula formation.In this case report we describe the diagnosis and treatment of the first case of esophago-bronchial fistula due to heterotopic gastric mucosa in mid esophagus.A 40-year old former professional soccer player was referred to our department for treatment of an esophago-bronchial fistula.Microscopic examination of the biopsies taken from the esophageal fistula revealed the presence of gastric heterotopic mucosa.We decided to do a non-surgical therapeutic endoscopic procedure.A sclerotherapy catheter was inserted through which 1 mL of ready to use synthetic surgical glue was applied in the fistula and it closed the fistula opening with excellent results. | Konstantinos H Katsanos Dimitrios K Christodoulou Sevasti Kamina Kosmidou Maria Evangelia Lambri Stavroula Theodorou Konstantinos Tsampoulas Mitsi Vasiliki Epameinondas V Tsianos | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，4： | 2 |
| 5 | Effects of seed moisture content, stratification and sowing date on the germination of Corylus avellana seeds显示文摘For Corylus avellana, pericarp permeability,seed desiccation tolerance, and the effect of warm and cold moist stratification combinations on germination and of outdoor sowing date on dormancy breaking and seedling emergence were investigated. Seeds with(intact fruit nut)and without the pericarp were subjected to an imbibition test, and water uptake was measured. After nuts had been stored for 5 months at 3–5℃, seeds and desiccated seeds were cold-stratified at 3–5 ℃(for 0, 1, 2 or 3 months),then tested for germination. Nuts were warm-stratified at 20–25℃(for 0, 1 or 2 months), then cold-stratified(for 0,1, 2 or 3 months) and tested for seed germination. The nuts were sown outdoors on three dates in the same year of their collection: 15 September(immediately after collection), 2 November, and 17 December, and emerged seedlings were counted the following spring. The pericarp was not a barrier to water uptake by the seed;however, the seeds imbibed water faster and had more mass when the pericarp was removed. Seeds tolerated desiccation;germinationpercentage was not reduced when seed moisture content was reduced to 8.71%. Germination of seeds without the pericarp(regardless of the moisture content) was the highest when the seeds were cold-stratified for 2 months.When seeds with the pericarp were tested for germination,2 months of warm stratification before a 2-month cold stratification maximized seed germination. For outdoor sowing of nuts, sowing date affected percentage of seedling emergence the following spring;early autumn sowing(immediately after collection) resulted in the best emergence. | Elias Pipinis Athanasios Stampoulidis Elias Milios Kyriaki Kitikidou Sofia Akritidou Stavroula Theodoridou Kalliopi Radoglou | 2020 | Journal of Forestry Research2020，31，3： | 2 |
| 6 | 在不含酒精的脂肪肝疾病和尖锐 ischemic 击严厉和结果之间的协会显示文摘 AIM:To evaluate the association of nonalcoholic fatty liver disease(NAFLD)with acute ischemic stroke severity and in-hospital outcome.METHODS:We prospectively studied all patients who were admitted in our Department with acute ischemic stroke between September 2010 and August 2012(n=415;39.5%males,mean age 78.8±6.6 years).The severity of stroke was assessed with the National Institutes of Health Stroke Scale(NIHSS)score at admission.NALFD was defined as serum alanine aminotransferase and/or aspartate aminotransferase levels above the upper limit of normal in the absence of other causes of elevated aminotransferases levels[chronic hepatitis B or C,drug toxicity,increased alcohol consumption(>21 and>14 drinks per week in men and women,respectively),cholestatic diseases or rhabdomyolysis].The outcome was assessed with the modified Rankin scale(mRS)score at discharge and in-hospital mortality.Adverse outcome was defined as mRS score at discharge≥2.Dependency at discharge was defined as mRS score between 2 to 5.RESULTS:NAFLD was present in 7.7%of the study population.Patients with NAFLD had lower serum high-density lipoprotein cholesterol and higher triglyceride levels than patients without NAFLD(P<0.05 for both comparisons).Demographic data,the prevalence of other cardiovascular risk factors and the prevalence of established CVD did not differ between the two groups.At admission,the NIHSS score did not differ between patients with and without NAFLD(6.3±6.4and 8.8±9.6,respectively;P=NS).At discharge,the mRS score did not differ between the two groups(1.9±2.2 and 2.6±2.2 in patients with and without NAFLD,respectively;P=NS).Rates of dependency at discharge were also similar in patients with and without NAFLD(36.8%and 55.0%,respectively;P=NS)as were the rates of adverse outcome(42.9%and58.6%,respectively;P=NS).In-hospital mortality rates also did not differ between the 2 groups(8.0%and 7.0%in patients with and without NAFLD,respectively;P=NS).CONCLUSION:The presence of NAFLD in patients admitted for acute ischemic stroke does not appear to be associated with more severe stroke or with worse in-hospital outcome. | Konstantinos Tziomalos Vasilios Giampatzis Stella D Bouziana Marianna Spanou Maria Papadopoulou Athinodoros Pavlidis Stavroula Kostaki Andreas Bozikas Christos Savopoulos Apostolos I Hatzitolios | 2013 | World Journal of Hepatology2013，5，11： | 2 |
| 7 | Photo- electrocatalytic hydrogen production by water splitting u- sing BiVO4 photoanodes 显示文摘 | Olivier M Lucian-Cristian P Stavroula S | 2016 | Chem Engineer J2016，286，： | 1 |
| 8 | CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes显示文摘 | Leonidas Benetatos Eleftheria Hatzimichael Aggeliki Dasoula George Dranitsaris Stavroula Tsiara Maria Syrrou Ioannis Georgiou Konstantinos L. Bourantas | 2009 | Leukemia Research2009，，： | 1 |
| 9 | Use of cyclodextrins as chiral selectors for direct resolution of the enantiomers of fluoxetine and its metabolite norfluoxetine by HPLC显示文摘 | Stavroula Piperaki Maria Parissi-Poulou | | 0，，04： | 1 |
| 10 | Lowdose Unenhanced Multidetoctor CT of Patients with Suspected Renal Colic显示文摘 | Denis Tack Stavroula Sourtzis Isabelle Delpierre | 2003 | AJR2003，180，： | 1 |
| 11 | Reactivation of severely aged three-way catalysts by washing with显示文摘 | Stavroula Y Christou H Birgersson H | 2007 | Weak EDTA and Oxalic Acid Solutions2007，，71： | 1 |
| 12 | Assessment of Prealbumin in Hemodialysis and Renal-Transplant Patients显示文摘 | Stavroula Chrysostomou Chalalambos Stathakis George Petrikkos George Daikos Athina Gompou Despina Perrea | 2010 | Journal of Renal Nutrition2010，，1： | 1 |
| 13 | Machine Learning in Predicting Printable Biomaterial Formulations for Direct Ink Writing显示文摘Three-dimensional(3D)printing is emerging as a transformative technology for biomedical engineering.The 3D printed product can be patient-specific by allowing customizability and direct control of the architecture.The trial-and-error approach currently used for developing the composition of printable inks is time-and resource-consuming due to the increasing number of variables requiring expert knowledge.Artificial intelligence has the potential to reshape the ink development process by forming a predictive model for printability from experimental data.In this paper,we constructed machine learning(ML)algorithms including decision tree,random forest(RF),and deep learning(DL)to predict the printability of biomaterials.A total of 210 formulations including 16 different bioactive and smart materials and 4 solvents were 3D printed,and their printability was assessed.All ML methods were able to learn and predict the printability of a variety of inks based on their biomaterial formulations.In particular,the RF algorithm has achieved the highest accuracy(88.1%),precision(90.6%),and F1 score(87.0%),indicating the best overall performance out of the 3 algorithms,while DL has the highest recall(87.3%).Furthermore,the ML algorithms have predicted the printability window of biomaterials to guide the ink development.The printability map generated with DL has finer granularity than other algorithms.ML has proven to be an effective and novel strategy for developing biomaterial formulations with desired 3D printability for biomedical engineering applications. | Hongyi Chen Yuanchang Liu Stavroula Balabani Ryuji Hirayama Jie Huang | 2023 | Research2023，，4： | 1 |
| 14 | Disorders of the plantar aponeeurosis: A spectrum of MR imaging findings 显示文摘 | Daphne J Theodnrou Stavroula J | 2001 | A JR2001，176，： | 1 |
| 15 | Biphenotypie acute leukemia following intensive adjuvant chemotherapy for breast cancer: case report and review of the lit- erature显示文摘 | Evangelos Briasoulls Evangelia Tzouvara Stavroula Tsiara | 2003 | The Breast Journal2003，9，： | 1 |
| 16 | Prod- uct Cost Estimation: Technique Classification and Metcho- dology Review 显示文摘 | NIAZI Adrian DAI Jian S BALABANI Stavroula | 2006 | Journal of Manufacturing Science and Engineering2006，128，2： | 1 |
| 17 | Synthesis and characterization of novel poly(propy- lene terephthalate co-adipate) biodegradable random copolyesters显示文摘 | Papageorgiou George Z Nanaki Stavroula G Bikiaris Dimitrios N | 2010 | Polymer Degradation and Stability2010，95，4： | 1 |
| 18 | Reliability constrained unit commitment using simulated annealing 显示文摘 | DIMITRIS N S STAVROULA D K COSTAS D V | 2006 | IEEE Trans on Power Systems2006，21，4： | 1 |
| 19 | An imaging overview of primary tumors of the spine: part 2. Malignant tumors显示文摘 | Daphne J. Theodorou Stavroula J. Theodorou David J. Sartoris | 2008 | Clinical Imaging2008，，3： | 1 |
| 20 | Evaluation of solid sorbents for the determination of fenhexamid, metalaxyl-M, pyrimethanil, malathion and myclobutanil residues in air samples显示文摘 | Nikolaos G. Tsiropoulos Evangelos B. Bakeas Vasilios Raptis Stavroula S. Batistatou | 2006 | Analytica Chimica Acta2006，，： | 1 |
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