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| 1 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012，30，2： | 32 |
| 2 | High-fat-induced intestinal permeability dysfunction associated with altered fecal bile acids显示文摘AIM:To investigate whether high-fat-feeding is associated with increased intestinal permeability via alterations in bile acid metabolism.METHODS:Male C57Bl/6J mice were fed on a high-fat (n=26) or low-fat diet (n=24) for 15 wk.Intestinal permeability was measured from duodenum,jejunum,ileum and colon in an Ussing chamber system using 4 kDa FITC-labeled dextran as an indicator.Fecal bile acids were analyzed with gas chromatography.Segments of jejunum and colon were analyzed for the expression of farnesoid X receptor (FXR) and tumor necrosis factor (TNF).RESULTS:Intestinal permeability was significantly increased by high-fat feeding in jejunum (median 0.334 for control vs 0.393 for high-fat,P=0.03) and colon (0.335 for control vs 0.433 for high-fat,P=0.01),but not in duodenum or ileum.The concentration of nearly all identified bile acids was significantly increased by high-fat feeding (P<0.001).The proportion of ursodeoxycholic acid (UDCA) in all bile acids was decreased (1.4%±0.1% in high-fat vs 2.8%±0.3% in controls,P<0.01) and correlated inversely with intestinal permeability (r=-0.72,P=0.01).High-fat feeding also increased jejunal FXR expression,as well as TNF expression along the intestine,especially in the colon.CONCLUSION:High-fat-feeding increased intestinal permeability,perhaps by a mechanism related to bile acid metabolism,namely a decreased proportion of fecal UDCA and increased FXR expression. | Lotta K Stenman Reetta Holma Riitta Korpela | 2012 | World Journal of Gastroenterology2012，18，9： | 19 |
| 3 | Role of the tumor-associated trypsin inhibitor SPINK1 in cancer development显示文摘 | Ulf-Hakan Stenman | 2011 | Asian Journal of Andrology2011，13，4： | 6 |
| 4 | CEA, CA199 and CA724 improve the diagnostic accuracy in gastrointestinal cancers 显示文摘 | Carpelan- Holmstrom M Louhimo J Stenman UH | 2002 | Anticancer Res2002，22，4： | 1 |
| 5 | Changes in serum concentrations of soluble vascular endothelial growth factor receptor-1 after pregnancy显示文摘 | Wathen KA Sarvela J Stenman F | 2011 | Hum Reprod2011，26，1： | 1 |
| 6 | CEA,CA242,CA19-9,CA72-4 and hCGbeta in the diagnosis of recurrentcolorectal cance显示文摘 | Carpelan-Holmstrm M Louhimo J Stenman UH | 2004 | Tumour Biol2004，25，5： | 1 |
| 7 | Cerebral is chemical up-regulates vascular endothelin ET(B) receptors in rat显示文摘 | Stenman E Malmojo M Uddman E | 2002 | Stroke2002，33，9： | 1 |
| 8 | Chromosomal localization of three human genes encoding bone morphogenetic protein receptors显示文摘 | Anna-Karin ?str?m Donald Jin Takeshi Imamura Eva R?ijer Bradley Rosenzweig Kohei Miyazono Peter ten Dijke G?ran Stenman | 1999 | Mammalian Genome1999，，3： | 1 |
| 9 | Determination of 25-hydrox- yvitamin D in serum byHPLC and immtmoassay 显示文摘 | Turpeinen U Hohenthal U Stenman U | 2003 | Clinical Chemistry2003，49，9： | 1 |
| 10 | Expression of the ERBB2 protein in benign and malignant salivary gland tumors 显示文摘 | Stenman G Sandros J Nordkvist A | 1991 | Genes Chromosomes Cancer1991，3，2： | 1 |
| 11 | Cerebral ischemia enhances vascular angiotensin AT1 receptor-mediated contraction in rats显示文摘 | Stenman E Edvinsson L | 2004 | Stroke2004，35，4： | 1 |
| 12 | A complexbetween PSA and a 1-antichymotrypsin is the major form of PSA in serum of patients with prostatic cancer:assay of the complex improves clinical sensitivity for cancer显示文摘 | Stenman U Leinonen J Alfthan H | 1991 | Cancer Res1991，51，1： | 1 |
| 13 | Determination of urinary free cortisol by liquid chromatography-tandem mass spectrometry显示文摘 | Turpeinen U Stenman UH Turpeinen U | 2003 | 63(2):143-502003，63，2： | 1 |
| 14 | Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon 显示文摘 | Stenman J Yu RT Evans RM | 2003 | Development2003，130，6： | 1 |
| 15 | HER2-testing in 538 consecutive breast cancer cases using FISH and immunohistochemistry显示文摘 | Kov a cs A Stenman G | 2010 | Pathol Res Pract2010，206，1： | 1 |
| 16 | Polychlorinated diphenyl ethers,dibenzo-p-dioxins dibenzofurans and biphenyls in seals and sedimentfromthe Gulf of Finland显示文摘 | Koistinen J Stenman O Haahti H | 1997 | Chemosphere1997，35，6： | 1 |
| 17 | A System for stabilizing the scintillation spectrometer显示文摘 | Stenman F | 1964 | Nuclear instruments and methods1964，29，1： | 1 |
| 18 | Determination of 25-hydroxyvitamin D in serum by HPLC and immunoassay显示文摘 | Turpeinen U Hohenthal U Stenman UH | | 0，，01： | 1 |
| 19 | Experimental evaluation and improvements to linear scan register allocation显示文摘 | Sagonas K Stenman E | | 0，，： | 1 |
| 20 | Comparison of abdominal and vaginal sonography insuspected ectopic pregnancy显示文摘 | Cacciatore B Stenman UH Ylostalo P | 1989 | Obstet Gynecol1989，73，7： | 1 |
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