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| 1 | Advances in Male Contraception显示文摘 | Stephanie T. Page John K. Amory William J. Bremner | 2008 | Endocrine Reviews2008,,4: | 2 |
| 2 | 【特刊综述】雄激素和前列腺疾病显示文摘越来越多的文献认同睾酮治疗在性腺机能低下患者中具有促合成代谢作用。而关于老年男性使用外源性雄激素的风险和其对前列腺潜在副作用的研究数据仍然匮乏。老年和性腺机能低下男性接受睾酮治疗是否会加重下尿路症状或加剧、揭露,甚至刺激前列腺癌发展,这一问题使采用睾酮治疗的热情有所减缓,与此同时前列腺疾病被视作睾酮治疗的相对禁忌。雄激素对于前列腺的发育和维护是必要的。无论如何,流行病学研究并没有一致地发现内源性血清雄激素浓度与前列腺疾病风险之间存在正相关。虽然最新研究显示5α还原酶抑制剂降低了患低级别前列腺癌的风险,说明抑制雄激素代谢有利于前列腺健康,但是对于高级别前列腺癌并没有类似作用,因此对这些药物化学预防的真正临床效益提出了质疑。鉴于缺乏大样本随机试验,很难了解如何最好地研究雄激素和前列腺疾病发展之间的关系。越来越多研究质疑雄激素在血清中的变化与其在前列腺激素环境中的变化有类似效应或者改变腺体内雄激素的调节过程。需要长期的干预性研究来真正证实雄激素对前列腺组织和疾病风险的操控。然而,现有数据认为恢复血清雄激素至生理水平并不会触发前列腺疾病。 | Lori A Cooper Stephanie T Page | 2014 | Asian Journal of Andrology2014,16,2: | 2 |
| 3 | Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies显示文摘 | Alida Ault Alyse M. Zajac Wing-Pui Kong J. Patrick Gorres Michael Royals Chih-Jen Wei Saran Bao Zhi-yong Yang Stephanie E. Reedy Tracy L. Sturgill Allen E. Page Jennifer Donofrio-Newman Amanda A. Adams Udeni B.R. Balasuriya David W. Horohov Thomas M. Cham | 2012 | Vaccine2012,,26: | 1 |
| 4 | Male pattern baldness and prostate cancer risk in a population-based case–control study显示文摘 | Jonathan L. Wright Stephanie T. Page Daniel W. Lin Janet L. Stanford | 2010 | Cancer Epidemiology2010,,2: | 1 |
| 5 | Higher testosterone levels are associated with increased highdensity lipoprotein cholesterol in men with cardiovascular disease: results from the Massachusetts Male Aging Study显示文摘瞄准:学习在传播雄激素之间的关系(全部的睾丸激素[TT ] ,免费睾丸激素[英尺] 并且 dihydrotestosterone [DHT ]) 并且在有或没有 CVD 的人的高级数据链路控制。方法:代表性的分析包括了 1 从马萨诸塞男老化学习(MMAS ) 的 661 件基线样品,人的一个基于人口的队变老 40-70 年。浆液荷尔蒙被放射性免疫测定测量,高级数据链路控制被决定跟随更低的密度脂蛋白的降水。CVD 被自我报告决定。分析用多重线性回归被执行。结果:TT 和高级数据链路控制断然在全部样品被相关(r= 0.11, P= 0.0001 ) 。在为反对创始人调整以后,我们发现这种关系主要与 CVD 被限制到 209 个人。在有 CVD 的人之中, TT (P= 0.0004 ) ,英尺(P= 0.0172 ) 和 DHT (P= 0.0128 ) 都断然与高级数据链路控制被相关,而在没有 CVD 的人仅仅 TT 与高级数据链路控制(P= 0.0099 ) 相关。结论:我们的结果建议如果雄激素在中年的人贡献 CVD,效果不与高级数据链路控制上的内长的 T 的镇压效果有关。 | Stephanie T. Page Beth A. Mohr Carol L. Link Amy B. O'Oonnell William J. Bremner John B. McKinlay | 2008 | Asian Journal of Andrology2008,10,2: | 1 |
| 6 | Androgens exert sexually dimorphic effects on angiogenesis: novel insight into the relationship between androgens and cardiovascular disease显示文摘 | Katya B Rubinow John K Amory Stephanie T Page | 2011 | Asian Journal of Andrology2011,13,4: | 1 |
| 7 | Diagnostic role of fractional exhaled nitric oxide in pediatric eosinophilic esophagitis, relationship with gastric and duodenal eosinophils显示文摘BACKGROUND Eosinophilic esophagitis(EoE)is an eosinophilic-predominant inflammation of the esophagus diagnosed by upper endoscopy and biopsies.A non-invasive and cost-effective alternative for management of EoE is being researched.Previous studies assessing utility of fractional exhaled nitric oxide(FeNO)in EoE were low powered.None investigated the contribution of eosinophilic inflammation of the stomach and duodenum to FeNO.AIM To assess the utility of FeNO as a non-invasive biomarker of esophageal eosinophilic inflammation for monitoring disease activity.METHODS Patients aged 6-21 years undergoing scheduled upper endoscopy with biopsy for suspected EoE were recruited in our observational study.Patients on steroids and with persistent asthma requiring daily controller medication were excluded.FeNO measurements were obtained in duplicate using a chemiluminescence nitric oxide analyzer(NIOX MINO,Aerocrine,Inc.;Stockholm,Sweden)prior to endoscopy.Based on the esophageal peak eosinophil count(PEC)/high power field on biopsy,patients were classified as EoE(PEC≥15)or control(PEC≤14).Mean FeNO levels were correlated with presence or absence of EoE,eosinophil counts on esophageal biopsy,and abnormal downstream eosinophilia in the stomach(PEC≥10)and duodenum(PEC≥20).Wilcoxon rank-sum test,Spearman correlation,and logistic regression were used for analysis.P value<0.05 was considered significant.RESULTS We recruited a total of 134 patients,of which 45 were diagnosed with EoE by histopathology.The median interquartile range FeNO level was 17 parts per billion(11-37,range:7-81)in the EoE group and 12 parts per billion(8-19,range:5-71)in the control group.After adjusting for atopic diseases,EoE patients had significantly higher FeNO levels as compared to patients without EoE(Z=3.33,P<0.001).A weak yet statistically significant positive association was found between the number of esophageal eosinophils and FeNO levels(r=0.30,P<0.005).On subgroup analysis within the EoE cohort,higher FeNO levels were noted in patients with abnormal gastric(n=23,18 vs 15)and duodenal eosinophilia(n=28,21 vs 14);however,the difference was not statistically significant.CONCLUSION After ruling out atopy as possible confounder,we found significantly higher FeNO levels in the EoE cohort than in the control group. | Panamdeep Kaur Rachel Chevalier Craig Friesen Jamie Ryan Ashley Sherman Stephanie Page | 2023 | World Journal of Gastrointestinal Endoscopy2023,15,5: | 0 |
| 8 | 通勤显示文摘肯恩和丽莉如何去上班?他们谈论了各种通勤方式。 | Marcia Fry Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 9 | 哪个比较好?显示文摘苏希与丽莉谈论开车和搭乘大众交通工具。哪一种方式比较好呢? | Marcia Fry Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 10 | 爱车失踪显示文摘艾朗开车在他朋友的公寓大楼下绕了又绕。“我一点也不想念这个城市。根本就找不到停车位嘛!”他这么埋怨道。艾朗现在住在乡下.他的房子在一条安静的街道上.附近有条河。他从来不用担心停车位的事。当艾朗开到转角.突然肴见一个停车位就马上停了进去。然后他走进公寓跑上楼到他朋友詹姆士的家。艾朗敲敲门,詹姆士开门并说:“你终于来了,我开始担心起来了呢。” | Ruth Devlin Stephanie Chang(page design) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 11 | 春节快乐!显示文摘丽莉和同事谈论农历新年。 | Ruth Devlin Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 12 | 庆祝农历新年显示文摘丽莉向卡萝和肯恩说了更多的春节庆祝活动, | Ruth Devlin Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 13 | 早起或熬夜?显示文摘罗柏与丽莉各有不同的习惯。其中一人习惯早起.另一人经常熬夜。 | Beth Wei Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 14 | Androgen receptor deficiency in monocytes/ macrophages does not alter adiposity or glucose homeostasis in male mice显示文摘 | Katya B Rubinow Barbara Houston Shari Wang Leela Goodspeed Kayoko Ogimoto Gregory J Morton Christopher McCarty Robert E Braun Stephanie T Page | 2018 | Asian Journal of Andrology2018,20,3: | 0 |
| 15 | 做计划显示文摘苏希和肯恩是不一样的人。其中一人喜欢做计划,另外一人则不喜欢。 | Beth Wei Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 16 | 不同个性显示文摘罗柏与卡萝谈论害羞内向与热情外向。 | Beth Wei Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 17 | 爱困玛莉显示文摘玛莉的妈蚂走进她的房间说:“玛莉.起床喽!”玛莉一动也不动,静静地躺在那里。 | Ruth Devlin Stephanie Chang(page design) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 18 | 体育活动显示文摘罗伯与苏希谈论体育活动。 | Ruth Devlin Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 19 | 超级杯足球赛显示文摘罗柏与肯恩谈论超级杯足球赛 | Ruth Devlin Stephanie Chang(page design) 陈信宏(译) | 2012 | 空中英语教室(初级版.大家说英语)2012,,1: | 0 |
| 20 | Testicular fine-needle aspiration for the assessmen' of intratesticular hormone concentrations显示文摘在人的 intratesticular 性类固醇集中的测量两个都通知发展和男不孕的理解男神经质的避孕药。给使用侵略技术测量阴囊的荷尔蒙生理学的挑战,我们的组使用了一种最低限度地侵略的好针的渴望技术在正常的健康的人测量 intratesticular 荷尔蒙。此处,我们在场安全的 hoc 以后的分析和阴囊的好针的渴望(FNA ) 的功效作为六临床的试用的部分完成了。从 2001 通过 2011, 404 过程的一个总数在 163 个研究志愿者,其 85.9% 个在为 intratesticular 类固醇集中的测量获得足够的液体成功之中被进行。疼痛严重程序的疼痛地是最普通的副作用,与与中等程序的疼痛联系的 36.8% 过程和 4.7% 。Postprocedural 疼痛在一些天以内不平常、减退。温和本地檫伤与 14.9% 过程发生了。二个严肃的不利事件(0.5%) 要求了外科的干预。一个不利事件的风险没与把发成送气音的液体的年龄,身体团索引,阴囊的尺寸,或卷被联系。为 intratesticular 类固醇集中的测量获得液体的阴囊的 FNA 经常,对中等程序的疼痛温和的原因,而是严肃的不利事件很少发生。阴囊的 FNA 为定义人的 intratesticular 荷尔蒙生理学是有帮助的并且是为为关于阴囊的生理学和病理的研究获得液体的一个最低限度地侵略的、安全、有效方法。 | Ada P Lee Mara Y Roth Jean-Jacques Nya-Ngatchou Kat Lin Thomas J Walsh Stephanie T Page Alvin M Matsumoto William J Bremner John K Amory Bradley D Anawalt | 2016 | Asian Journal of Andrology2016,18,1: | 0 |