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| 1 | Radial artery access site complications during cardiac procedures,clinical implications and potential solutions: The role of nitric oxide显示文摘Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery,as this is considered to be safer than the femoral approach.However,despite improvements in technology and techniques,complications can occur.The most common complication,arterial spasm,can cause intense pain and,in some cases,procedural failure.The incidence of spasm is dependent on several variables,including operator experience,artery size,and equipment used.An antispasmolytic cocktail can be applied to reduce spasm,which usually includes an exogenous nitric oxide(NO)donor(glyceryl trinitrate).NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm intervention.However,systemic administration can result in unwanted side-effects,such as hypotension.A method that adopts local delivery of NO might be advantageous.This review article describes the mechanisms involved in radial artery spasm,discusses the advantages and disadvantages of current strategies to reduce spasm,and highlight the potential of NO-loaded nanoporous materials for use in this setting. | Emma M Coghill Timothy Johnson Russell E Morris Ian L Megson Stephen J Leslie | 2020 | World Journal of Cardiology2020，12，1： | 4 |
| 2 | Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db / db Mice显示文摘 | Hong Chen Olga Charlat Louis A Tartaglia Elizabeth A Woolf Xun Weng Stephen J Ellis Nathan D Lakey Janice Culpepper Karen J More Roger E Breitbart Geoffrey M Duyk Robert I Tepper Jay P Morgenstern | 1996 | Cell1996，，3： | 2 |
| 3 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011，，13： | 2 |
| 4 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://gffzz783b6e01a04243c3hwv9v5wwqpvun6nvo.ffgz.tsg.suse.edu.cn/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016，3，1： | 2 |
| 5 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011，，9779： | 2 |
| 6 | Computer simulations of electrokinetic injection techniques in microfluidic devices 显示文摘 | Sergey V E Stephen C J Ramsey J M | 2000 | Anal Chem2000，72，15： | 1 |
| 7 | Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality 显示文摘 | SHARON M MAO H STEPHENS E etal | 2009 | Structure2009，17，1： | 1 |
| 8 | Epigeneticevents underlie‘pathogenesis of sinonasal papillomas显示文摘 | STEPHEN J K VAUGHT L E CHEN K M | 2007 | Modern Pathology2007，20，： | 1 |
| 9 | Resistance spot welding of aluminum alloy to steel with transition material显示文摘 | Sun X Stephens E V Khaleel M A | 2004 | Welding Journal2004，83，6： | 1 |
| 10 | In situ investigation of the calcium-induced proteolytic and salting-in mechanisms causing tenderization in calcium-enhanced muscle显示文摘 | Lawrance T E Dikeman M E Stephens J W | 2003 | Meat Sci2003，66，： | 1 |
| 11 | Inference of population structure using multilocus genotype data显示文摘 | Pritchard J K Stephens M DotmeUy E 2000 | 2000 | Genetics2000，155，2： | 1 |
| 12 | Cocoa extract protects against early lcohol-induced liver injury in the rat显示文摘 | Akira K Erwin G | 2002 | Archives of Biochemistry and Biophysics2002，406，： | 1 |
| 13 | Effects of fusion zone size and failure mode on peak load and energy absorption of advanced high strength steel spot welds under lap shear loading conditions显示文摘 | Sun X Stephens E V Khaleel M A | 2008 | Engineering Failure Analysis2008，15，4： | 1 |
| 14 | Maternal and foetal immune responses of cattle following an experimental challenge with Neospora caninum at day 70 of gestation显示文摘 | PAUL M B STEPHEN E W STEPHEN W M | 2012 | Vet Res2012，43，1： | 1 |
| 15 | An open-label pilot study of high-concentration capsaicin patch in painful HIV neuropathy显示文摘 | David M S Lydla E Stephen J B | 2008 | Journal of Pain and Symptom Management2008，35，3： | 1 |
| 16 | Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars 显示文摘 | Cavanagh CS Chao S Wang BE Huang BE Stephen S Kiani S Forrest K Saintenac C Brown-Guedira GL Akhunova A See D Bai G Pumphrey M Tomar L Wong D Kong S Reynolds M da Silva ML Bockelman H Talbert L Anderson JA Dreisigacker S Baenziger S Carter A Korzun V Morrell PL Dubcovsky J Morell MK Sorrells ME Hayden MJ Akhunov E | 2013 | PNAS2013，110，： | 1 |
| 17 | Fatigue be- haviors of self-piercing rivets joining similar and dissimilar sheet metals 显示文摘 | SUN X STEPHENS E V KHALEEL M | 2007 | International Journal of Fatigue2007，29，2： | 1 |
| 18 | A com- parison of surface water natural organic matter in raw filtered wa- ter samples, XAD, and reverse osmosis isolates 显示文摘 | PATRICIA A M M1VHAEL J P STEPHEN E C | 2002 | Water Re- search2002，36，： | 1 |
| 19 | Multi-Agent systems for power engineering applications-Part 1 : concepts, approaches and technical challenges显示文摘 | Stephen D McArthur J Davidson E M | 2007 | IEEE Trans on Power Systems2007，22，4： | 1 |
| 20 | Nanoscale Atoms in Solid- State Chemistry 显示文摘 | Roy X Lee C H Crowther A C Schenck C L Besara T Lalancette R A Siegrist T Stephens P W Brus L E Kim P Steigerwald M L Nuckolls C | 2013 | Science2013，，341： | 1 |
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