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| 1 | Systematic review of novel ablative methods in locally advanced pancreatic cancer显示文摘Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis.Current standard therapy is limited to chemotherapy or chemoradiotherapy.Few regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently needed.Thermal and laser based ablative techniques are widely used in many solid organ malignancies.Initial studies in the pancreas were associated with significant morbidity and mortality,which limited widespread adoption.Modifications to the various applications,in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in safety.We conducted a systematic review of the litera-ture up to October 2013.Initial studies suggest that ablative therapies may confer an additional survival benefit over best supportive care but randomised studies are required to validate these findings. | Margaret G Keane Konstantinos Bramis Stephen P Pereira Giuseppe K Fusai | 2014 | World Journal of Gastroenterology2014，20，9： | 30 |
| 2 | Advanced non-alcoholic steatohepatitis cirrhosis: A high-risk population for pre-liver transplant portal vein thrombosis显示文摘AIM To examine if liver transplant recipients with high-risk non-alcoholic steatohepatitis(NASH) are at increased risk for pre-transplant portal venous thrombosis.METHODS Data on all liver transplants in the United States from February 2002 through September 2014 were analyzed. Recipients were sorted into three distinct groups: High-risk(age > 60, body mass index > 30 kg/m2, hypertension and diabetes), low-risk and non-NASH cirrhosis. Multivariable logistic regression models were constructed.RESULTS Thirty-five thousand and seventy-two candidates underwent liver transplantation and of those organ recipients, 465 were transplanted for high-risk and 2775 for lowrisk NASH. Two thousand six hundred and twentysix(7.5%) recipients had pre-transplant portal vein thrombosis; 66(14.2%) of the high-risk NASH group had portal vein thrombosis vs 328(11.8%) of the lowrisk NASH group. In general, all NASH recipients were less likely to be male or African American and more likely to be obese. In adjusted multivariable regression analyses, high-risk recipients had the greatest risk ofpre-transplant portal vein thrombosis with OR = 2.11(95%CI: 1.60-2.76, P < 0.001) when referenced to the non-NASH group.CONCLUSION Liver transplant candidates with high-risk NASH are at the greatest risk for portal vein thrombosis development prior to transplantation. These candidates may benefit from interventions to decrease their likelihood of clot formation and resultant downstream hepatic decompensating events. Prospective study is needed. | Jonathan G Stine Curtis K Argo Shawn J Pelletier Daniel G Maluf Stephen H Caldwell Patrick G Northup | 2017 | World Journal of Hepatology2017，9，3： | 2 |
| 3 | Substrate specificity of the Eschc- richia coli outer membrane protease OmpT 显示文摘 | McCarter JD Stephens D Shoemaker K Rosenberg S Kitsch JF Georgiou G | 2004 | J Bacteriol2004，186，17： | 1 |
| 4 | Cocoa extract protects against early lcohol-induced liver injury in the rat显示文摘 | Akira K Erwin G | 2002 | Archives of Biochemistry and Biophysics2002，406，： | 1 |
| 5 | The Influence of the Spouse on American Expatriate Adjustment and Intent to Stay in Pacific Rim Overseas Assignments 显示文摘 | BLACK J S STEPHENS G K | 1989 | Journal of Management1989，15，4： | 1 |
| 6 | Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars 显示文摘 | Cavanagh CS Chao S Wang BE Huang BE Stephen S Kiani S Forrest K Saintenac C Brown-Guedira GL Akhunova A See D Bai G Pumphrey M Tomar L Wong D Kong S Reynolds M da Silva ML Bockelman H Talbert L Anderson JA Dreisigacker S Baenziger S Carter A Korzun V Morrell PL Dubcovsky J Morell MK Sorrells ME Hayden MJ Akhunov E | 2013 | PNAS2013，110，： | 1 |
| 7 | Occupational carbon monox- ide poisoning in Washington State, 2000-2005 显示文摘 | Carolyn K David K Stephen G | 2010 | Journal of Oc- cupational and Environmental Hygiene2010，7，： | 1 |
| 8 | Ultrafast and direct imprint of nanostructures in silicon显示文摘 | Stephen Y C Chris K Jian G | 2002 | Nature2002，417，20： | 1 |
| 9 | Sy- stematic evaluation of in vitro and in vivo adventitious virus assays for the detection of viral contamination of cell banks and biological products 显示文摘 | JAMES G STEPHEN K PAULA NGOMBOLD J et ai | 2014 | Vaccine2014，32，24： | 1 |
| 10 | Initial Tension in Randomly Disordered Periodic Lattices显示文摘 | Karpov E G Stephen N G Liu W K | | 0，，20： | 1 |
| 11 | The influanee of the spouse on A- merican expatiate adjustment and intent to stay in pacific rim o- verseas assignments 显示文摘 | BLACK J S STEPHENS G K | 1989 | Journal of Management1989，15，4： | 1 |
| 12 | Initial tension inrandomly disordered periodic lattices 显示文摘 | Karpov E G Stephen N G Liu W K | 2003 | InternationalJournal of Solids and Structures2003，40，20： | 1 |
| 13 | Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2 显示文摘 | Dhamrait SS Stephens JW Cooper JA Acharya J Mani AR Moore K Miller G J Humphries S E Hurel S J Montgomery H E | 2004 | Europe heart2004，25，： | 1 |
| 14 | A new polarized atmospheric radiative transfer model显示文摘 | EVANS K F STEPHENS G L | 1991 | J of Quantitative Spectroscopy and Radiative Transfer1991，46，5： | 1 |
| 15 | Evolution of an Agricul- tural Innovation: The N-Trak Soil Nitrogen Test Adopt and Discon- tinue, or Reject? 显示文摘 | Kathy S K Michael C Stephen G | 2001 | Technology in Society2001，23，1： | 1 |
| 16 | Natural area visitors' place meaning and place attachment ascribed to a marine setting 显示文摘 | Christopher J W Gerard T K Stephen G S | 2012 | Journal of Environmental Psychology2012，32，4： | 1 |
| 17 | Zeolite for-mation in alkali-activated cementitious systems显示文摘 | MICHAEL G STEPHEN K MARIA D | | 0，，： | 1 |
| 18 | A dynamic model for requirements planning with application to supply chain optimization显示文摘 | Stephen C G David B K | 1998 | Operations Research1998，46，3： | 1 |
| 19 | Do starting and ending effects in fixed-price group-buying differ?显示文摘 | Zhou G Xu K Q Stephen S Y | 2013 | Electronic Commerce Research and Applications2013，12，2： | 1 |
| 20 | An Analysis of Inter- change Operation in an Urban Automated Highway Net- work显示文摘 | STEPHEN J K ROBERT G S | 1972 | Transportation Research1972，6，4： | 1 |
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