|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 在 7T 的多原子的磁性的回声光谱学的应用显示文摘 AIM: To discuss the advantages of ultra-high field (7T) for 1H and 13C magnetic resonance spectroscopy (MRS) studies of metabolism.made at both 3 and 7T using 1H MRS. Measurements of glycogen and lipids in muscle were measured using 13C and 1H MRS respectively. RESULTS: In the brain, increased signal-to-noise ratio (SNR) and dispersion allows spectral separation of the amino-acids glutamate, glutamine and γ-aminobutyric acid (GABA), without the need for sophisticated editing sequences. Improved quantification of these me-tabolites is demonstrated at 7T relative to 3T. SNR was 36% higher, and measurement repeatability (% coefficients of variation) was 4%, 10% and 10% at 7T, vs 8%, 29% and 21% at 3T for glutamate, glutamine and GABA respectively. Measurements at 7T were used to compare metabolite levels in the anterior cingulate cortex (ACC) and insula. Creatine and glutamate levels were found to be significantly higher in the insula compared to the ACC (P < 0.05). In muscle, the increased SNR and spectral resolution at 7T enables interleaved studies of glycogen (13C) and intra-myocellular lipid (IMCL) and extra-myocellular lipid (EMCL) (1H) following exercise and refeeding. Glycogen levels were sig-nificantly decreased following exercise (-28% at 50% VO2 max; -58% at 75% VO2 max). Interestingly, levels of glycogen in the hamstrings followed those in the quadriceps, despite reduce exercise loading. No changes in IMCL and EMCL were found in the study. CONCLUSION: The demonstrated improvements in brain and muscle MRS measurements at 7T will increase the potential for use in investigating human metabolism and changes due to pathologies. | Mary C Stephenson Frances Gunner Antonio Napolitano Paul L Greenhaff Ian A MacDonald Nadeem Saeed William Vennart Susan T Francis Peter G Morris | 2011 | World Journal of Radiology2011，3，4： | 2 |
| 2 | Inhibition of rous scrcoma virus replication and cell transformation by a specific oligodeoxymucleotide显示文摘 | Zameenik P C Stephenson M L | 1978 | Proc Natl Acad Sci USA1978，75，1： | 1 |
| 3 | Performance of floating and sunken media biological aerated filters under unsteady state conditions显示文摘 | Mann A T Mendoza-Espinosa L Stephenson T | 1999 | Water Research1999，33，4： | 1 |
| 4 | Repetitive functionalization of water-soluble single-walled carbon nanotubes: Addition of acid-sensitive addends 显示文摘 | Stephenson J J Hudson J L Leonard A D | 2007 | Chem-istry of Materials2007，19，14： | 1 |
| 5 | Life-cy- cle Assessment of Potential Algal Biodiesel Production in the United Kingdom:A Comparison of Raceways and Air-lift Tubular Bioreactors显示文摘 | STEPHENSON A L KAZAMIA E DENNIS J S | 2010 | Energy & Fuels2010，24，7： | 1 |
| 6 | High-resolution ^13C CP/MAS NMR spectra of solid cellulose oligomers and the structure of cellulose II显示文摘 | DUDLEY R L FYFE C A STEPHENSON P J | 1983 | Journal of the American Chemical Society1983，105，8： | 1 |
| 7 | A comparison of floating and sunken media biological aerated filters for nitrification 显示文摘 | Mann A Mendoza-Espinosa L Stephenson T | 1998 | Journal of Chemical Technology and Biotechnology1998，72，3： | 1 |
| 8 | Effect of influent organic content on digested sludge extracellular polymer content and dewaterability 显示文摘 | Houghton J l Stephenson T | 2002 | Water Research2002，36，14： | 1 |
| 9 | Ul-traviolet (UV) disinfetion of grey water: Particle size effects显示文摘 | Winward G P Avery L M Stephenson T | 2008 | Enviromental Technology2008，29，2： | 1 |
| 10 | A rapid accurate assay for choline kinase显示文摘 | ULANE R E STEPHENSON L L FARRELL P M | 1977 | Anal Biochem1977，79，12： | 1 |
| 11 | Glutathione conjugation: a detoxification pathway for fenoxapropethyl in barley, crabgrass, oat and wheat显示文摘 | TAL J A ROMANO M L STEPHENSON G R | 1993 | Pestic Biochem Physiol1993，46，： | 1 |
| 12 | Mycorrhizae form Denali National Park and Reserve, Alaska 显示文摘 | Treu R Laursen G A Stephenson S L | 1996 | Mycorrhiza1996，6，： | 1 |
| 13 | Effect of twin-row planting pattern and plant density on cotton growth, yield, and fiber quality 显示文摘 | STEPHENSON D O BARBER T L BOURLAND F M | 2011 | The Journal of Cotton Science2011，15，： | 1 |
| 14 | Individualized single walled carbon nanotubes from bulk material using 96% sulfuric acid as solvent显示文摘 | STEPHENSON J J HUDSON J L AZAD S | 2006 | Chemistry of Materials2006，18，2： | 1 |
| 15 | Forecast veriti cation: current status and future directions显示文摘 | Casati B Wilson L J Stephenson D B | 2008 | Meteotological Applications2008，15，： | 1 |
| 16 | Theoretical study of heat transfer in two- dimensional turbulent flow in a circular pipe and between parallel and diverging plates显示文摘 | | 1976 | Int J Heat Mass Transfer1976，19，： | 1 |
| 17 | A soluble ribonucleic acid intermediate in protein synthesis 显示文摘 | HOAGLAND M B STEPHENSON M L SCOTT J F | 1958 | J Biol Chem1958，231，1： | 1 |
| 18 | C-Clbond fission,HCl elimination,and secondary radical decomposition in the 193 nm photodissociation of allyl chloride显示文摘 | Morton M L Butler L J Stephenson T A | 2002 | Journal of Chemical Physics2002，116，： | 1 |
| 19 | Inhibition of Rous sarcoma virus replication and transformation by a specific oligodeoxynucleotide显示文摘 | ZAMECNIK P C STEPHENSON M L | 1978 | Proc Natl Acad Sci USA1978，75，1： | 1 |
| 20 | Nutrient bioassimilation capacity of aquacultured oysters: quantification of an ecosystem service显示文摘 | Higgins C B Stephenson K Brown B L | 2011 | Journal of Environmental Quality2011，40，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员