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| 1 | Selecting suitable solid organ transplant donors: Reducing the risk of donor-transmitted infections显示文摘Selection of the appropriate donor is essential to a successful allograft recipient outcome for solid organ transplantation. Multiple infectious diseases have been transmitted from the donor to the recipient via transplantation. Donor-transmitted infections cause increased morbidity and mortality to the recipient. In recent years, a series of high-profile transmissions of infections have occurred in organ recipients prompt-ing increased attention on the process of improving the selection of an appropriate donor that balances the shortage of needed allografts with an approach that mitigates the risk of donor-transmitted infection to the recipient. Important advances focused on improving donor screening diagnostics, using previously excluded high-risk donors, and individualizing the selection of allografts to recipients based on their prior infection history are serving to increase the donor pool and improve outcomes after transplant. This article serves to review the relevant literature surrounding this topic and to provide a suggested approach to the selection of an appropriate solid organ transplant donor. | Christopher S Kovacs Jr Christine E Koval David van Duin Amanda Guedes de Morais Blanca E Gonzalez Robin K Avery Steven D Mawhorter Kyle D Brizendine Eric D Cober Cyndee Miranda Rabin K Shrestha Lucileia Teixeira Sherif B Mossad | 2014 | World Journal of Transplantation2014，4，2： | 7 |
| 2 | BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization显示文摘BCL2 最好作为多功能的 anti-apoptotic 蛋白质被知道。然而,很少在房间粘合剂和活动性事件对它的角色被知道。这里,我们证明 BCL2 可以在房间粘附的规定起一个作用,传播,并且活动性。BCL2 什么时候是在有教养的鼠科、人的房间线,传播的房间,粘附,和活动性的 overexpressed,被损害。与这些结果一致, Bcl2 的损失导致了在 Bcl2 空的老鼠观察的更高的活动性与野类型相比的胚胎的成纤维细胞(MEF ) 房间。房间粘附和活动性的 BCL2 规定的机制可以包含包含 BCL2,肌动朊,和 gelsolin 的建筑群的形成,它看起来机能上地减少 gelsolin 的切断的活动。我们观察到从 overexpressed BCL2 提高了的 MCF-7 和 NIH3T3 房间的 lysate 肌动朊聚合在在 vitro 试金没有房间。BCL2 和 F 肌动朊的共焦的 immunofluorescent 本地化在一致地传播期间证明 BCL2 的那增加的表情导致了增加的 F 肌动朊聚合。因此, BCL2 和 gelsolin 建筑群的形成(它可能包含另外的蛋白质) 看起来在房间粘附和移植的规定起一个关键作用。与癌症转移给房间活动性的确定的关联,这结果可以解释在一些肿瘤房间类型的 BCL2 的表示为什么为转移减少潜力并且与改进耐心的预后被联系。 | Hengning Ke Vandy I Parron Jeff Reece Jennifer Y Zhang Steven K Akiyama John E French | 2010 | Cell Research2010，20，4： | 3 |
| 3 | Shoot and root traits in drought tolerant maize(Zea mays L.) hybrids显示文摘This study aimed to investigate the differences in shoot and root traits, and water use and water use efficiency(WUE) in drought tolerant(DT) maize(Zea mays L.) hybrids under full and deficit irrigated conditions. A two-year greenhouse study was conducted with four hybrids(one conventional hybrid, 33D53AM, two commercial DT hybrids, P1151 AM, N75H, and an experimental hybrid, Exp HB) grown under two water regimes(I_(100) and I_(50), referring to 100 and 50% of evapotranspiration requirements). Under water stress, the hybids P1151 AM, N75, and Exp HB showed more drought tolerance and had either greater shoot dry weight or less dry weight reduction than the conventional hybrid(33 D53 AM). However, these three hybrids responded to water stress using different mechanisms. Compared with the conventional hybrid, the two commercial DT hybrids(P1151 AM and N75H) had a smaller leaf area, shoot dry weight, and root system per plant. As a result, these hybrids used less water but had a higher WUE compared with the conventional hybrid. In contrast, the experimental hybrid(ExpHB) produced more shoot biomass by silking stage at both irrigation levels than all other hybrids, but it had relatively lower WUE. The hybrids demonstrated different drought response mechanisms that may require different irrigation management strategies. More investigation and validation are needed under field conditions and in different soil types. | ZHAO Jin XUE Qing-wu Kirk E Jessup HOU Xiao-bo HAO Bao-zhen Thomas H Marek XU Wen-wei Steven R Evett Susan A O'Shaughnessy David K Brauer | 2018 | Journal of Integrative Agriculture2018，17，5： | 3 |
| 4 | Association of types of diabetes and insulin dependency on birth outcomes显示文摘BACKGROUND Diabetes rates among pregnant women in the United States have been increasing and are associated with adverse pregnancy outcomes.AIM To investigate differences in birth outcomes(preterm birth,macrosomia,and neonatal death)by diabetes status.METHODS Cross-sectional design,using linked Missouri birth and death certificates(singleton births only),2010 to 2012(n=204057).Exposure was diabetes non-diabetic,pre-pregnancy diabetes-insulin dependent(PD-I),pre-pregnancy diabetes-non-insulin dependent(PD-NI),gestational diabetes-insulin dependent(GD-I),and gestational diabetes-non-insulin dependent(GD-NI).Outcomes included preterm birth,macrosomia,and infant mortality.Confounders included demographic characteristics,adequacy of prenatal care,body mass index,smoking,hypertension,and previous preterm birth.Bivariate and multivariate logistic regression assessed differences in outcomes by diabetes status.RESULTS Women with PD-I,PD-NI,and GD-I remained at a significantly increased odds for preterm birth(aOR 2.87,aOR 1.77,and aOR 1.73,respectively)and having a very large baby[macrosomia](aOR 3.01,aOR 2.12,and aOR 1.96,respectively);in reference to non-diabetic women.Women with GDNI were at a significantly increased risk for macrosomia(aOR1.53),decreased risk for their baby to die before their first birthday(aOR 0.41)and no difference in risk for preterm birth in reference to non-diabetic women.CONCLUSION Diabetes is associated with the poor birth outcomes.Clinical management of diabetes during pregnancy and healthy lifestyle behaviors before pregnancy can reduce the risk for diabetes and poor birth outcomes. | Pamela K Xaverius Steven W Howard Deborah Kiel Jerry E Thurman Ethan Wankum Catherine Carter Clairy Fang Romi Carriere | 2022 | World Journal of Clinical Cases2022，10，7： | 2 |
| 5 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 6 | Efficacy of interferon-gamma and amphotericin B for the treatment of systemic murine histoplasmosis显示文摘 | Clemons K V Lutz J E Stevens D A | 2001 | Microbes Infect2001，3，： | 1 |
| 7 | Ankle: isotropic MR imagingwith 3D-FSE-cube-initial experience in healthy volunteers显示文摘 | Stevens K J Busse R F Han E | 2008 | Radi-ology2008，249，3： | 1 |
| 8 | Degradation of zao dye by environmental microorganisms and helminthes 显示文摘 | Chung K T Stevens S E | 1993 | Environ Toxical Chem1993，13，11： | 1 |
| 9 | Fast accurate fuzzy clustering through data reduction 显示文摘 | Steven E Jing W K Lawrence O | 2003 | IEEE Trans on Fuzzy Systems2003，11，2： | 1 |
| 10 | Solid-phase extraction fractionation to extend the characterization of naphthenic acids in crude oil by electro spray ionization fourier transform ion cyclotron resonance mass spectrometry显示文摘 | Rowland Steven M Robbins Winston K Corilo Yuri E | 2014 | Energy and Fuels2014，28，8： | 1 |
| 11 | Review article mechanisms linking obesity to insulin resistance and type 2 diabetes显示文摘 | Steven E Hull RL Utzschneider K M | 2006 | Na- ture2006，44，： | 1 |
| 12 | Diversity,Pathoge- nicity,and Management of Verticillium Species显示文摘 | Steven J K Zahi K A Gary E V | 2009 | Annu Rev Phytopat hol2009，47，： | 1 |
| 13 | Comparison of the gravimetric,phenol red, and 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model显示文摘 | Steven C S Rinaldi M T Vukovinsky K E | 2001 | AAPS Pharm Sci2001，3，3： | 1 |
| 14 | 显示文摘 | STEVEN E W DANIEL H E HOUK K N | 2008 | J Phys Chem A2008，112，： | 1 |
| 15 | Volatile constituents in guava显示文摘 | Stevens K L Brekke J E Stern D J | 1970 | Journal of Agriculture and Food Chemistry1970，18，： | 1 |
| 16 | Snyder-Mackler,L,Binder-Macleod,S A Maximum voluntary activation in nonfatigued and fatigued muscle of young and elderly individuals显示文摘 | STACKHOUSE S K STEVENS J E LEE S C | 2001 | Physical Therapy2001，81，5： | 1 |
| 17 | Common variation in Nemo-like kinase is associated with risk of ovarian cancer显示文摘 | Stevens K N Kelemen L E Wang X Fridley B L Vierkant R A Fredericksen Z | 2012 | Cancer Epidemiol Biomarkers Prev2012，21，： | 1 |
| 18 | A practical twostep quantitative clinical and ehetrophysiologieal assessment for the diagnosis and staging of diabetle neuropathy 显示文摘 | Feldman E L Stevens M J Thomas P K | 1994 | Diabetes Care1994，17，11： | 1 |
| 19 | Pathophysiology and pharmacotherapy of gastroparesis:current and future perspec- tives显示文摘 | Stevens J E Jones K L Rayner C K et aI | 2013 | Expert Opin Pharmacother2013，14，： | 1 |
| 20 | Analysis of pursuit tracking eye movements in pilots and nonfliers 显示文摘 | ENGELKEN E J STEVENS K W BELL A F | 1994 | Biomedical Sciences Instrumentation1994，30，： | 1 |
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