5篇
您的检索式：作者名="Steven Solga"
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| 1 | N-acetylcysteine treats intravenous amiodarone induced liver injury显示文摘We report a case of intravenous(IV) amiodarone drug induced liver injury(DILI).The patient received IV N-acetylcysteine(NAC) which resulted in a rapid improvement in liver enzymes.While the specific mechanisms for the pathogenesis of IV amiodaroneDILI and the therapeutic action of IV NAC are both unknown, this case strongly implies at least some commonality.Because IV amiodarone is indicated for the treatment of serious cardiac arrhythmias in an intensive care unit setting, some degree of ischemic hepatitis is likely a cofactor in most cases. | Matthew L Mudalel Kartikeya P Dave James P Hummel Steven F Solga | 2015 | World Journal of Gastroenterology2015，21，9： | 5 |
| 2 | Breath volatile organic compounds for the gut-fatty liver axis: promise, peril, and path forward显示文摘The worldwide interest in the gut microbiome and its impact on the upstream liver highlight a critical upside to breath research: it can uniquely measure otherwise unmeasurable biology. Bacteria make gases [volatile organic compounds(VOCs)] that are directly relevant to pathophysiology of the fatty liver and associated conditions, including obesity. Measurement of these VOCs and their metabolites in the exhaled breath, therefore, present an opportunity to safely and easily evaluate, on both a personal and a population level, some of our most pressing public health threats. This is an opportunity that must be pursued. To date, however, breath analysis remains a slowly evolving field which only occasionally impacts clinical research or patient care. One major obstacle to progress is that breath analysis is inherently and emphatically mutli-disciplinary: it connects engineering, chemistry, breath mechanics, biology and medicine. Unbalanced or incomplete teams may produce inconsistent and often unsatisfactory results. A second impediment is the lack of a well-known stepwise structure for the development of non-invasive diagnostics. As a result, the breath research landscape is replete with orphaned single-center pilot studies. Often, important hypotheses and key observations have not been pursued to maturation. This paper reviews the rationale and requirements for breath VOC research applied to the gut-fatty liver axis and offers some suggestions for future development. | Steven Francis Solga | 2014 | World Journal of Gastroenterology2014，20，27： | 3 |
| 3 | Dietary Composition and Nonalcoholic Fatty Liver Disease显示文摘 | Steven Solga Amir R. Alkhuraishe Jeanne M. Clark Mike Torbenson Ashli Greenwald Anna Mae Diehl Thomas Magnuson | 2004 | Digestive Diseases and Sciences2004，，10： | 2 |
| 4 | Can imaging modalities diagnose and stage hepatic fibrosis and cirrhosis accurately? 显示文摘 | Susanne Bonekamp Ihab Kamel Steven Solga | 2009 | Hepatology2009，50，1： | 1 |
| 5 | Non-alcoholic fatty liver disease: lumen–liver interactions and possible role for probiotics显示文摘 | Steven F. Solga A.M. Diehl | 2003 | Journal of Hepatology2003，，5： | 1 |
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