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| 1 | 代谢产物右旋羟戊二酸抑制FTO/m6A/Myc/CEBPA通路的抗肿瘤作用显示文摘贝克曼研究所陈建军教授、芝加哥大学生化研究所何川教授、浙江大学附属第一医院血液科金洁教授及其研究团队合作发现:异柠檬酸脱氢酶(ISOdehydrogenase,IDH)突变造成的代谢产物右旋羟戊二酸(R-2-hydroxyglutarate,R-2HG)通过抑制FTO/m6A/Myc/CEBPA信号发挥抗白血病的作用。2011年,何川教授实验室证实肥胖相关蛋白(obesity-associated protein,FTO)是m6A去甲基转移酶。m6A是一种广泛存在的RNA修饰,参与RNA的剪接、转位、衰减、翻译等过程,参与维持机体稳态,并与疾病的发生发展密切相关,如肿瘤、炎症相关疾病等。FTO调节肿瘤的具体机制需要进一步被揭示。 | 朱哈 刘娟 Su R Dong L Li C | 2018 | 中国肿瘤生物治疗杂志2018，25，2： | 62 |
| 2 | Cadherin-17:一种消化道腺癌诊断的有效标记显示文摘 | Su M C Yuan R H Lin C Y 饶秋(摘译) | 2008 | 临床与实验病理学杂志2008，24，5： | 26 |
| 3 | Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma显示文摘瞄准:在整个 Barretts 食管的前进调查 cyclooxygenase-2 (COX-2 ) 和上皮的生长因素受体(EGFR ) 的表示() 。方法:COX-2 和 EGFR 蛋白质表情被使用免疫检测组织化学的方法。详细 cytomorphological 改变的 A 是坚定的。COX-2 和 EGFR 表示的区域被使用计算机成像系统确定。结果:COX-2 和 EGFR 的表情与前进一起增加了从到食管腺癌(EAC ) 。积极关联在 COX-2 表示和 EGFR 表示之间被发现。结论:COX-2 和 EGFR 可能在逐步的前进从是合作的到 EAC,从而导致致癌作用。 | Yan Li John M Wo Mukunda B Ray Whitney Jones Ruifeng R Su Susan Ellis Robert C G Martin | 2006 | World Journal of Gastroenterology2006，12，6： | 14 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 5 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 6 | A novel drought-inducible gene,A TAF1,encodes a NAC family protein that negatively regulates the expression of stress-responsive genes in Arabidopsis显示文摘 | LU P L CH EN N Z AN R SU Z QI B S REN F CHEN J WANG X C | 2007 | Plant Molecular Biology2007，63，2： | 1 |
| 7 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 8 | Pricing American options: A comparison of MonteCarlo simulation approaches显示文摘 | Fu M C Laprise S B Madan D B Su Y Wu R | 2001 | Journal of Computational Finance2001，4，： | 1 |
| 9 | Qualitative and quantitative determination of the major coumarins in Zushima by high performance liquid chrom atography with diode array detector and mass spectrometry 显示文摘 | SU J ZHANG C ZHANG W SH EN Y H LIH H LIU R H ZHANG X HU X J ZHANG W D | 2009 | J Chromatogr: A2009，1216，11： | 1 |
| 10 | Tubulointerstitial nephritis with uveitis in Chinese adults 显示文摘 | Li C Su T Chu R | 2014 | Clin J Am Soc Nephrol2014，9，1： | 1 |
| 11 | Plume impingement force during Tandem stage separation at high altitudes 显示文摘 | Su M W Mullen C R | 1972 | Journal of Spacecraft1972，9，9： | 1 |
| 12 | Actuat显示文摘 | Wei B Y Hsu M C Su P G Lin H M Wu R J Lai H J Sensor | 2004 | B2004，101，： | 1 |
| 13 | Free radical scavenging and apoptotic effects of Cordyceps sinensis fractionated by supercritical carbon dioxide显示文摘 | Wang B J Won S J Yu Z R Su C L | 2005 | Food Chem Toxicol2005，43，4： | 1 |
| 14 | 显示文摘 | Su C H Dudley M Matyi R | 2000 | Journal of Crystal Growth2000，208，14： | 1 |
| 15 | Component immunoaffinity subtraction chromatography: an inn vative step towards a comprehensive survey of the human plasma proteome 显示文摘 | PIEPER R SU Q GATLIN C L | 2003 | Proteomics2003，3，4： | 1 |
| 16 | On head-on collisions between two solitary waves显示文摘 | SU C H MIRIE M R | 1980 | Journal of Fluid Mechanics1980，98，： | 1 |
| 17 | Arsenate and Arsenite Removal by Zerovalent Iron : Effects of Phosphate, Silicate, Carbonate, Borate, Sulfate, Chromate, Molybdate, and Nitrate, Relative to Chloride 显示文摘 | Su C Puls R W | 2001 | Environmental Science & Technology2001，35，22： | 1 |
| 18 | Effects of pressure on the emission of CaWO4 : Eu^3+ phosphor 显示文摘 | Cheng X R Yuan C S Su L | 2014 | Optical Materials2014，37，0： | 1 |
| 19 | 显示文摘 | Wang C G Wang R S Su Z M | 2001 | Synth Met2001，119，： | 1 |
| 20 | The Kinetics of B-a and Pa Type Copelybenzoxazine Via the Ring Opening Process显示文摘 | SU Y C YEI D R CHANG F C | 2005 | J Appl Polym Sci2005，95，3： | 1 |
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