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| 1 | Vital roles of stem cells and biomaterials in skin tissue engineering显示文摘Tissue engineering essentially refers to technology for growing new human tissue and is distinct from regenerative medicine. Currently, pieces of skin are already being fabricated for clinical use and many other tissue types may be fabricated in the future.Tissue engineering was first defined in 1987 by the United States National Science Foundation which critically discussed the future targets of bioengineering research and its consequences. The principles of tissue engineering are to initiate cell cultures in vitro, grow them on scaffolds in situ and transplant the composite into a recipient in vivo. From the beginning, scaffolds have been necessary in tissue engineering applications. Regardless, the latest technology has redirected established approaches by omitting scaffolds. Currently, scientists from diverse research institutes are engineering skin without scaffolds. Due to their advantageous properties, stem cells have robustly transformed the tissue engineering field as part of an engineered bilayered skin substitute that will later be discussed in detail. Additionally, utilizing biomaterials or skin replacement products in skin tissue engineering as strategy to successfully direct cell proliferation and differentiation as well as to optimize the safety of handling during grafting is beneficial. This approach has also led to the cells' application in developing the novel skin substitute that will be briefly explained in this review. | Abu Bakar Mohd Hilmi Ahmad Sukari Halim | 2015 | World Journal of Stem Cells2015，7，2： | 2 |
| 2 | Antileukemic prop- erties of Spermacoce species 显示文摘 | Sukari M A Utami R Neoh B K | 2013 | Asian Journal of Chemistry2013，25，8： | 1 |
| 3 | Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line(CEMss)by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway,activation of caspase 3 and G2/M phase cell cycle arrest显示文摘 | Kuan-Beng Ng Ahmad Bustamam Mohd Aspollah Sukari | 2013 | BMC Complement Altern Med2013，13，1： | 1 |
| 4 | Dentatin isolated from Clausena excavata induces apoptosis in MCF - 7 ceils through the intrinsic pathway with involvement of NF - KB signalling and G0/G1 cell cycle arrest: a bioassay - guided approach显示文摘 | Arbab IA Abdul AB Sukari MA | 2013 | J Ethnopharmacol2013，145，1： | 1 |
| 5 | Two new xanthones from Artocarpus obtusus显示文摘 | Hashim N Rahmani M Sukari M A | 2010 | J Asian Nat Prod Res2010，12，2： | 1 |
| 6 | The growth suppressing effects of girinimbine on HepG2 involve induction of apoptosis and cell cycle arrest显示文摘 | Syam S Abdul AB Sukari MA | 2011 | Molecules2011，16，8： | 1 |
| 7 | Influence of non-thermal plasma forming gases on improvement of surface properties of low density polyethylene (LDPE)显示文摘 | K. Navaneetha Pandiyaraj R.R. Deshmukh Inci Ruzybayev S. Ismat Shah Pi-Guey Su Jr. mercy Halleluyah Ahmad Sukari Halim | 2014 | Applied Surface Science2014，，： | 1 |
| 8 | Tualang honey has higher phenolic content and greater radical scavenging activity compared with other honey sources显示文摘 | R. Krishna Kishore Ahmad Sukari Halim M.S.Nurul Syazana K.N.S. Sirajudeen | 2011 | Nutrition Research2011，，4： | 1 |
| 9 | Phenantridine alkaloids from Zanthoxylum myriacanthum显示文摘 | SUKARI M A SALIM W S W IBRAHIM N H | 1999 | Fitoterapia1999，70，： | 1 |
| 10 | Chitosan Dermal Substitute and Chitosan Skin Substitute Contribute to Accelerated Full-Thickness Wound Healing in Irradiated Rats显示文摘 | Abu Bakar Mohd Hilmi Ahmad Sukari Halim Hasnan Jaafar Abu Bakar Asiah Asma Hassan Esmaiel Jabbari | 2013 | BioMed Research International2013，，： | 1 |
| 11 | Characterization of the inclusion complex of zerumbone with hydroxypropyl-beta-cyclodextrin 显示文摘 | Eid E E M Abdul A B Suliman F E O Sukari M A Rasedee A Fatah S S | 2011 | Carbohydrate Polymers2011，83，4： | 1 |
| 12 | Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest显示文摘 | Syam Mohan Ahmad Bustamam Abdul Siddig Ibrahim Abdelwahab Adel S. Al-Zubairi Mohamed Aspollah Sukari Rasedee Abdullah Manal Mohamed Elhassan Taha Mohamed Yousif Ibrahim Suvitha Syam | 2010 | Journal of Ethnopharmacology2010，，3： | 1 |
| 13 | Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo显示文摘 | Syam Mohan Ahmad Bustamam Abdul Siddig Ibrahim Abdelwahab Adel S. Al-Zubairi Mohamed Aspollah Sukari Rasedee Abdullah Manal Mohamed Elhassan Taha Ng Kuan Beng Nurbaity Mohd Isa | 2010 | Leukemia Research2010，，11： | 1 |
| 14 | Inclusioncomplex of zerumbone with hydroxypropyl-p-cyclodextrininduces apoptosis in liver hepatocellular HepG2 cells via caspase8/BID cleavage switch and modulating Bcl2/Bax ratio显示文摘 | Muhammad Nadzri N Abdul AB Sukari MA | 2013 | EvidBased Complement Alternat Med2013，2013，81： | 1 |
| 15 | The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo : Possible involvement of indirect antioxidant action显示文摘 | Siddig Ibrahim Abdelwahab Syam Mohan Mahmmod Ameen Abdulla Mohd Aspollah Sukari Ahmad Bustamam Abdul Manal Mohamed Elhassan Taha Suvitha Syam Syahida Ahmad Ka-Heng Lee | 2011 | Journal of Ethnopharmacology2011，，2： | 1 |
| 16 | Induction of selective cytotoxicity and apoptosis in human T4 - lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest 显示文摘 | Ng KB Bustamam A Sukari MA | 2013 | BMC Complementary and Ahernative Medicine2013，13，： | 1 |
| 17 | Inclusion Complex of Zerumbone with Hydroxypropyl-beta-Cyclodextrin InducesApoptosis in Liver Hepatocellular HepG2 Cells via Caspase-8/BID Cleavage Switch andModulating Bcl2/Bax Ratio 显示文摘 | Muhammad NN Abdul AB Sukari MA | 2013 | Evid Based Complement Altemat Med2013，2013，16： | 1 |
| 18 | 原代培养过程中壳聚糖衍生物对CTCF/YB-1/C-myc和p53蛋白表达的影响显示文摘成功建立了人增生性瘢痕细胞和正常皮肤成纤维细胞的原代培养,并利用热休克蛋白(HSP47)和成纤维细胞特异蛋白(FSP)标记物进行了鉴定。研究发现,经过壳聚糖衍生物处理,人增生性瘢痕成纤维细胞和正常皮肤成纤维细胞在培养中均出现了不同类型的蛋白表达。多功能转录因子蛋白(CTCF)在壳聚糖衍生物处理的增生性瘢痕成纤维细胞中出现表达上调;在聚糖衍生物处理的正常皮肤成纤维细胞中数量无变化。YB-1结合蛋白在经壳聚糖处理的正常皮肤成纤维细胞与人增生性瘢痕细胞中的表达几乎无异,但在未经壳聚糖处理的细胞中表达不同。C-MYC和P53蛋白在壳聚糖衍生物处理的增生性瘢痕纤维细胞中表达上调,但在正常皮肤成纤维细胞中,无论是否经过壳聚糖衍生物处理,这两种蛋白都没有表达。上述4种蛋白在人增生性瘢痕细胞和正常皮肤成纤维细胞中表现出不同的表达方式,这种新型壳聚糖衍生物可能在控制人增生性瘢痕细胞和正常皮肤成纤维细胞生长和增殖过程中起着重要作用。这些蛋白因子的表达机制目前还不是完全清楚,有待于进一步研究。 | Mohammad Syaiful Bahari Abdull Rasad Ahmad Sukari Halim Kamaruddin Hashim Ahmad Hazri Abdul Rashid Lim Chin Keong Shaharum Shamsuddin | 2008 | 生物工程学报2008，24，12： | 0 |
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