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| 1 | Role of dental plaque,saliva and periodontal disease in Helicobacter pylori infection显示文摘Helicobacter pylori(H.pylori)infection is one of the most common bacterial infections in humans.Although H.pylori may be detected in the stomach of approximately half of the world’s population,the mechanisms of transmission of the microorganism from individual to individual are not yet clear.Transmission of H.pylori could occur through iatrogenic,fecal-oral,and oral-oral routes,and through food and water.The microorganism may be transmitted orally and has been detected in dental plaque and saliva.However,the role of the oral cavity in the transmission and recurrence of H.pylori infection has been the subject of debate.A large number of studies investigating the role of oral hygiene and periodontal disease in H.pylori infection have varied significantly in terms of their methodology and sample population,resulting in a wide variation in the reported results.Nevertheless,recent studies have not only shown that the microorganism can be detected fairly consistently from the oral cavity but also demonstrated that the chances of recurrence of H.pylori infection is more likely among patients who harbor the organism in the oral cavity.Furthermore,initial results from clinical trials have shown that H.pylori-positive dyspeptic patients may benefit from periodontal therapy.This paper attempts to review the current body of evidence regarding the role of dental plaque,saliva,and periodontal disease in H.pylori infection. | Pradeep S Anand Kavitha P Kamath Sukumaran Anil | 2014 | World Journal of Gastroenterology2014，20，19： | 15 |
| 2 | Phytochemical constituents and antibacterial efficacy of the flowers of Peltophomm pterocarpum(DC.) Baker ex Heyne显示文摘Objective:To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum pterocarpum.Methods:Phytochemical analysis was done by using the standard methods given by Harbone.The methanolic flower extract were tested against Escherichia coli,Klebsiella pneumonia,Pseudomonas aeruginosa.Staphylococcus aureus. Bacillus cereus,Salmonella typhi,Serratia marsecens,Acinetobacter baumannii.Enterobacter sp., Proteus mirabilis.Enterococcus faecalis and Streptococcus pyogenes by the agar disc diffusion method.Results:Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds,flavonoids.saponins,steroids,tannins,xanthoproteic,carboxylic acids, coumarins and carbohydrates.The flower extract of Peltophorum pteroearpum showed significant activity against four gram positive(Staphylococcus aureus.Bacillus cereus.Enlerococcus faecalis and Streptococcus pyogenes) and three gram negative bacteria(Proteus mirabilis,Acinetohacter baumannii and Serratia marsecens).out of 12 pathogenic bacteria studied.Conclusion:The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pleracarpum. | Sukumaran S Kiruba S Mahesh M Nisha SR Miller Paul Z Ben CP Jeeva S | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 4 |
| 3 | Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: Possible involvement of PKC–MAPK signaling pathway显示文摘 | Vivian Soetikno Flori R. Sari Vijayakumar Sukumaran Arun Prasath Lakshmanan Sayaka Mito Meilei Harima Rajarajan A. Thandavarayan Kenji Suzuki Masaki Nagata Ritsuo Takagi Kenichi Watanabe | 2012 | European Journal of Pharmaceutical Sciences2012，，3： | 2 |
| 4 | Incidence,types, risk factors, and outcome of stroke in a developingcountry: the Trivandrum Stroke Registry 显示文摘 | Sridharan SE Unnikrishnan JP Sukumaran S | 2009 | Stroke2009，40，4： | 1 |
| 5 | Himalayan sedimentary pulses recorded by silicate detritus within a fer- romanganese crust from the Central Indian Ocean显示文摘 | Banakar V K Galy A Sukumaran N P | 2003 | Earth and Planetary Science Letters2003，205，3： | 1 |
| 6 | Method of Determining Cold Hardiness by Electrical Conductivity in Potato显示文摘 | Sukumaran N P Weiser C J | | 0，，07： | 1 |
| 7 | Efficient on the fly calculation of time correlation functions in computer simulations显示文摘 | Ramirez J Sukumaran S K Vorselaars B | 2010 | J Chern Phys2010，133，15： | 1 |
| 8 | The effect of isothermal mechanical stirring on an Al-Si alloy in the semisolid condition 显示文摘 | SUKUMARAN K PAI B C CHAKRABORTY M | 2004 | Materials Science and Engineering A2004，369，： | 1 |
| 9 | Role of immune dysfunction in drug induced liver injury显示文摘Drug-induced liver injury(DILI)is one of the leading causes of liver failure and withdrawal of drugs from the market.A poor understanding of the precipitating event aetiology and mechanisms of disease progression has rendered the prediction and subsequent treatment intractable.Recent literature suggests that some drugs can alter the liver’s repair systems resulting in injury.The pathophysiology of DILI is complex,and immune dysfunction plays an important role in determining the course and severity of the disease.Immune dysfunction is influenced by the host response to drug toxicity.A deeper understanding of these processes may be beneficial in the management of DILI and aid in drug development.This review provides a structured framework presenting DILI in three progressive stages that summarize the interplay between drugs and the host defence networks. | Chandrashekaran Girish Sukumaran Sanjay | 2021 | World Journal of Hepatology2021，13，11： | 1 |
| 10 | Prehospital trauma management:a national study of paramedic activities显示文摘 | Sukumaran JM Henry D Beard | | 0，，01： | 1 |
| 11 | Freezing Injury in Potato Leaves显示文摘 | Sukumaran N P and Weiser C J | 1972 | Plant Physiol1972，50，： | 1 |
| 12 | The effect of isothermal mechanical stirring on an A1-Si alloy in the semisolid condition显示文摘 | SUKUMARAN K PAl B C CHAKRABORTY M | 2004 | Materials Science and Engineering2004，369，12： | 1 |
| 13 | Bioethanol production from rice straw: An overview显示文摘 | Binod P Sindhu R Singhania RR Vikram S Devi L Nagalakshmi S Kurien N Sukumaran RK Pandey A | 2010 | Bioresource Technology2010，101，13： | 1 |
| 14 | Entry and intracellular replication of Escherichia coli K1 in macrophages require expression of outer membrane protein A 显示文摘 | Sukumaran SK Shimada H Prasadarao NV | 2003 | Infect Immun2003，71，10： | 1 |
| 15 | A comparison of canal preparation using the K - file and Lightspeed in resin blocks显示文摘 | Thamni SL Parameswaran A Sukumaran VG | 1996 | JEndod1996，22，： | 1 |
| 16 | An excise leaflet test for evaluating potato frost tolerance显示文摘 | Sukumaran N P | 1972 | Hortisci1972，，7： | 1 |
| 17 | An unusual cause of vaginal discharge following gender reassignment显示文摘 | SUKUMARAN S MORAN P A MAKAR A | 2009 | Int Urogynecol J Pelvic Floor Dysfunct2009，20，2： | 1 |
| 18 | Cellulase production using biomass feed stock and its application in lignocellulose saccharification for bio-ethanol production 显示文摘 | SUKUMARAN R K SINGHANIA R R MATHEW G M | 2009 | Renew Energ2009，34，2： | 1 |
| 19 | Stability of carious totl nutrient admixture formulations using Liposyn Ⅱ and AminosynⅡ显示文摘 | Sayeed FA Tripp MG Sukumaran KB | 1987 | Am J Hosp Pharm1987，44，： | 1 |
| 20 | Regulation of inflammation and myocardial fibrosis in experimental autoimmune myocarditis显示文摘 | Watanabe K Sukumaran V Veeraveedu P | 2011 | Inflamm Allergy Drug Targets2011，10，3： | 1 |
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