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| 1 | Sperm immobilization activity of Allium sativum L. and other plant extracts显示文摘Aim: To identify possible spermicidal agents through screening a number of edible medicinal plants with antimicrobial activity. Methods: Initial screening was made on the basis of ram cauda epididymal sperm immobiliza-tion immediately after addition of extracts. The most potent extract was selected and was evaluated on both ram and human spermatozoa. To unravel its mode of action several sperm functional tests were carried out, namely viability of cells, hypo-osmotic swelling test for membrane integrity and assays of membrane-bound enzyme 5'-nucleotidase and acrosomal marker enzyme acrosin. Results: The crude aqueous extract of the bulb ofAllium sativum L. Showed the most promising results by instant immobilization of the ram epididymal sperm at 0.25 g/mL and human ejaculated sperm at 0.5 g/mL. Sperm immobilizing effects were irreversible and the factor of the extract responsible for immobilization was thermostable up to 90℃. On boiling at 100℃ for 10 minutes, this activity was markedly reduced. Moreover, this extract was able to cause aggregation of ram sperms into small clusters after 30 minutes of incubation at 37℃. However this property was not found in human spermatozoa. More than 50 % reduction in sperm viability and hypo-osmotic swelling occurred in treated sperm as compared with the controls, indicating the possibility of plasma membrane disintegration which was further supported by the significant reduction in the activity of membrane bound 5''-nucleotidase and acrosomal acrosin. Conclusion: The crude aqueous extract of A. Sativum bulb possesses spermicidal activity in vitro. (Asian J Androl 2003 Jun, 5:131-135 ) | Kausiki Chakrabarti Sulagna Pal Asok K.Bhattacharyya | 2003 | Asian Journal of Andrology2003,5,2: | 4 |
| 2 | Minnelide reduces tumor burden in preclinical models of osteosarcoma显示文摘 | Sulagna Banerjee Venugopal Thayanithy Veena Sangwan Tiffany N. Mackenzie Ashok K. Saluja Subbaya Subramanian | 2013 | Cancer Letters2013,,2: | 1 |
| 3 | Kruppel-like factor 4, a novel transcription Factor regulates microglial activation and subsequent neuroinflammation显示文摘 | Deepak K Kaushik Malvika Gupta Sulagna Das | 2010 | Journal of Neuroinflammation2010,7,: | 1 |
| 4 | Triptolide Induces the Expression of miR-142-3p: A Negative Regulator of Heat Shock Protein 70 and Pancreatic Cancer Cell Proliferation显示文摘 | Tiffany N. MacKenzie Nameeta Mujumdar Sulagna Banerjee Veena Sangwan Aaron Sarver Selwyn Vickers Subbaya Subramanian Ashok K. Saluja | 2013 | Molecular Cancer Therapeutics2013,,7: | 1 |
| 5 | 迈克尔·菲尔普斯:一条有故事的“飞鱼”显示文摘他绰号'飞鱼',人人都说他生就一副游泳的好身板,认为他的成功完全是上天赐予。但你是否知道,一年365天,每天训练池里必定都有他努力的身影——'一想起训练,我就会掀开暖被,冲进刺骨的池水。'你是否知道,在闪光灯下的他,始终保有一颗平和心——'或许我更喜欢平静的生活,我想不出还有哪种生活方式比现在的更好。'付出终有回报。今年8月,他在第29届奥运会上一举夺得了8枚金牌。他就是迈克尔·菲尔普斯。 | Sulagna Dasgupta 郑衍文 | 2008 | 新东方英语(中学版)2008,0,10: | 0 |
| 6 | Numerical analysis of non-isothermal viscous jet with peripheral heat transfer显示文摘A fluid jet ejected from micron size nozzle is a commonly occurring phenomenon in biomedical engineering,printing technology and micro-fluidic applications.Disintegration of a jet into drops occurs due to disturbances induced by external sources.This work explores the various sources of perturbation and their effect on jet disintegration through numerical simulation of a two-dimensional non-isothermal model.The mathematical approach uses a novel technique to combine analytical solutions for the energy balance equation in the radial direction to solve the complete two dimensional problem.The two dimensional energy balance equation is simultaneously solved together with the axi-symmetric Navier–Stokes equations using the slender-jet approximation to predict jet velocity.The energy balance takes into account of peripheral heat transfer to the environment through analytical expressions derived from radial approximations.The model helps in understanding the factors in dynamic temperature variations that eventually render the jet unstable.The distinguishing aspect of this work is the analysis of the effect of a periodic thermal perturbation applied at any point in the domain of a progressive jet,a situation typically encountered in thermal inkjet printers and not considered previously.Results presented for non-isothermal jets which are both stationary and moving illustrate the effect of jet velocity in propagation of perturbation and subsequent drop formation.The major contribution of this numerical study is that it provides an insight on novel ways of controlling droplet formation in bubble jet printers.This study demonstrates that thermal disturbance propagating from periodic heating can be manipulated to shape the droplets and control their breakage point along the jet. | Sulagna Chatterjee Trisha Sen Anindya Mitra | 2016 | International Journal of Modeling, Simulation, and Scientific Computing2016,7,3: | 0 |
| 7 | Comparative efficacy of ChatGPT 3.5,ChatGPT 4,and other large language models in gynecology and infertility research显示文摘Dear Editor,As experts in gynecology and infertility research,we have witnessed the rapid advancement of artificial intelligence(Al)technologies,particularly language models,which have greatly improved their capabilities.In this communication,we aim to compare the proficiency of advanced language models,such as Chat Generative Pre-Trained Transformer(ChatGPT)3.5,ChatGPT 4,and others,in relation to our field. | Pallav Sengupta Sulagna Dutta Srikumar Chakravarthi Ravindran Jegasothy Ravichandran Jeganathan Anuradha Pichumani | 2023 | Gynecology and Obstetrics Clinical Medicine2023,3,4: | 0 |