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| 1 | Long-term result of endoscopic Histoacryl (N-butyl-2-cyanoacrylate)injection for treatment of gastric varices显示文摘AIM:To evaluate the long-term efficacy and safety of endoscopic obliteration with Histoacryl for treatment of gastric variceal bleeding and prophylaxis.METHODS:Between January 1994 and March 2010 at SoonChunHyang University Hospital,a total of 127 patients with gastric varices received Histoacryl injections endoscopically.One hundred patients underwent endoscopic Histoacryl injections because of variceal bleeding,the other 27 patients received such injections as a prophylactic procedure.RESULTS:According to Sarin classification,56 patients were GOV1,61 patients were GOV2 and 10 patients were IGV.Most of the varices were large(F2 or F3,111 patients).The average volume of Histoacryl per each session was 1.7±1.3 cc and mean number of sessions was 1.3±0.6.(1 session-98 patients,2 sessions-25 patients,≥3 sessions-4 patients).Twenty-seven patients with high risk of bleeding(large or fundal or RCS+or Child C) received Histoacryl injection as a primary prophylactic procedure.In these patients,hepatitis B virus was the major etiology of cirrhosis,25 patients showed GOV1 or 2(92.6%)and F2 or F3 accounted for 88.9%(n=24).The rate of initial hemostasis was 98.4%and recurrent bleeding within one year occurred in 18.1%of patients.Successful hemostasis during episodes of rebleeding was achieved in 73.9%of cases.Median survival was 50 mo (95%CI 30.5-69.5).Major complications occurred in 4 patients(3.1%).The rebleeding rate in patients with hepatocellular carcinoma or GOV2 was higher than in those with other conditions.None of the 27 subjects who were treated prophylactically experienced treatment-related complications.Cumulative survival rates of the 127 patients at 6 mo,1,3,and 5 years were 92.1%,84.2%,64.2%,and 45.3%,respectively.The 6 mo cumulative survival rate of the 27 patients treated prophylactically was 75%.CONCLUSION:Histoacryl injection therapy is an effective treatment for gastric varices and also an effective prophylactic treatment of gastric varices which carry high risk of bleeding. | Eun Jung Kang Soung Won Jeong Jae Young Jang Joo Young Cho Sae Hwan Lee Hyun Gun Kim Sang Gyune Kim Young Seok Kim Young Koog Cheon Young Deok Cho Hong Soo Kim Boo Sung Kim | 2011 | World Journal of Gastroenterology2011，17，11： | 41 |
| 2 | Diagnostic value for extrahepatic metastases of hepatocellular carcinoma in positron emission tomography/computed tomography scan显示文摘AIM: To evaluated the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan in diagnosis of hepatocellular carcinoma (HCC) and extrahepatic metastases. METHODS: A total of 138 patients with HCC who had both conventional imaging modalities and 18F-FDG PET/CT scan done between November 2006 and March 2011 were enrolled. Diagnostic value of each imaging modality for detection of extrahepatic metastases was evaluated. Clinical factors and tumor characteristics including PET imaging were analyzed as indicative factors for metastases by univariate and multivariate methods. RESULTS: The accuracy of chest CT was significantly superior compared with the accuracy of PET imaging for detecting lung metastases. The detection rate of metastatic pulmonary nodule ≥ 1 cm was 12/13 (92.3%), when < 1 cm was 2/10 (20%) in PET imaging. The accuracy of PET imaging was significantly superior compared with the accuracy of bone scan for detecting bone metastases. In multivariate analy- sis, increased tumor size (≥ 5 cm) (P = 0.042) and increased average standardized uptake value (SUV) uptake (P = 0.028) were predictive factors for extrahepatic metastases. Isometabolic HCC in PET imaging was inversely correlated in multivariate analysis (P = 0.035). According to the receiver operating characteristic curve, the optimal cutoff of average SUV to predict extrahepatic metastases was 3.4. CONCLUSION: 18F-FDG PET/CT scan is invaluable for detection of lung metastases larger than 1 cm and bone metastases. Primary HCC having larger than 5 cm and increased average SUV uptake more than 3.4 should be considered for extrahepatic metastases. | Ji Eun Lee Jae Young Jang Soung Won Jeong Sae Hwan Lee Sang Gyune Kim Sang-Woo Cha Young Seok Kim Young Deok Cho Hong Soo Kim Boo Sung Kim So Young Jin Deuk Lin Choi | 2012 | World Journal of Gastroenterology2012，18，23： | 10 |
| 3 | Risk factors for hepatocellular carcinoma in patients with drug-resistant chronic hepatitis B显示文摘AIM:To investigate the risk factors and characteristics of hepatocellular carcinoma(HCC) in the patients with drug-resistant chronic hepatitis B(CHB).METHODS:A total of 432 patients with drug-resistant CHB were analyzed retrospectively from January 2004to December 2012. The patients were divided into two groups:the HCC group(n = 57) and the non-HCC group(n = 375). Two groups compared using logistic regression for various patients and viral characteristics in order to identify associated risk factors for HCC.Secondarily,patient and tumor characteristics of HCC patients with na ve CHB(N group,n = 117) were compared to the HCC group(R group,n = 57) to identify any difference in HCC characteristics between them.RESULTS:A significant difference was found for age,platelet count,alpha-fetoprotein(AFP),positivity of HBeAg,seroconversion rate of HBeAg,virologic response,the Child-Pugh score,presence of rtM204I,and the duration of antiviral treatment in non-HCC and HCC group. Cirrhosis,age(> 50 years),HBeAg(+),virologic non-responder status,and rtM204I mutants were independent risk factors for the development of HCC. The R group had lower serum C-reactive protein(CRP) and AFP levels,earlier stage tumors,and a shorter mean tumor surveillance period than the N group. However,the total follow-up duration was not significantly different between the two groups.CONCLUSION:13.2% of patients with drug-resistant CHB developed HCC. Age,cirrhosis,YIDD status,HBeAg status,and virologic response are associated with risk of HCC. Patients with drug-resistant CHB and these clinical factors may benefit from closer HCC surveillance. | Chung Hwan Jun Hyoung Ju Hong Min Woo Chung Seon Young Park Sung Bum Cho Chang Hwan Park Young Eun Joo Hyun Soo Kim Sung Kyu Choi Jong Sun Rew | 2013 | World Journal of Gastroenterology2013，19，40： | 7 |
| 4 | Change in Antibiotic Resistance of Helicobacter pylori Strains and the Effect of A2143G Point Mutation of 23S rRNA on the Eradication of H. pylori in a Single Center of Korea显示文摘 | Tae Jun Hwang Nayoung Kim Hong Bin Kim Byoung Hwan Lee Ryoung Hee Nam Ji Hyun Park Mi Kyoung Lee Young Soo Park Dong Ho Lee Hyun Chae Jung In Sung Song | 2010 | Journal of Clinical Gastroenterology2010，，8： | 5 |
| 5 | Understanding microstructure and mechanical properties of(AlTa(0.76))xCoCrFeNi(2.1) eutectic high entropy alloys via thermo-physical parameters显示文摘(AlTa(0.76))xCoCrFeNi(2.1)(x values in molar ratio,x=0.1,0.3,0.5,0.7,1.0,and 1.5) alloys were designed to investigate the microstructure and mechanical properties of the eutectic high entropy alloys(EHEAs)consisting of FCC,B2,and Laves phases.Depending on the compositional variatio,clear microstructural variation was observed,as follows:(1) Group 1:FCC dendrite+Laves interdendrite(x=0.1),(2) Group 2:FCC dendrite+fine-eutectic structure consisting of FCC and Laves phases(x=0.3,0.5 and 0.7),(3) Group 3:B2 dendrite+bimodal eutectic structure [FCC/B2+Laves](x=1.0),(4) Group 4:Laves dendrite+eutectic structure consisting of B2 and Laves phases(x=1.5).As the fraction of Laves or B2 phases increases,yield stress increases from 293 to 2336 MPa,while the plastic strain decreases from 50 % to 2%.Thermo-physical parameters,such as mixing entropy(△S(mix)),mixing enthalpy(△H(mix)),valence electron concentration(VEC),and atomic size difference(δr),were calculated to understand the microstructural variation.Two criteria(δr-VEC and δr-△H(mix)) were utilized to elucidate the formation of the eutectic structures in the present EHEAs,revealing the usefulness of the thermo-physical parameters in the development of EHEAs. | Min Jung Kim Gyeol Chan Kang Sung Hwan Hong Hae Jin Park Sang Chul Muna Gian Song Ki Buem Kim | 2020 | Journal of Materials Science & Technology2020，54，22： | 3 |
| 6 | New para-magnetic(CoFeNi)(50)(CrMo)(50-x)(CB)x(x=20,25,30)non-equiatomic high entropy metallic glasses with wide supercooled liquid region and excellent mechanical properties显示文摘In this study,high entropy metallic glasses(HEMGs)were developed through a combination of concepts for designing metallic glasses(main element+transition metal+metalloid element)and high-entropy alloys(more than five elements,each element having an atomic concentration between 5 at.%and 35 at.%).The developed metallic glass alloys are composed of Co-Fe-Ni main elements,transition metals(Cr,Mo)and metalloid elements(C,B).Moreover,the present work reports the thermal,mechanical and magnetic properties of(CoFeNi)(50)(CrMo)(50-x)(CB)x alloys with x=20,25,30.The developed as-spun HEMGs exhibit typical paramagnetic properties even for a high amount of ferromagnetic elements(Co,Fe,and Ni)and have high elastic modulus(103–160 GPa)and hardness(14–27 GPa),thus possessing mechanical properties similar to well-known Co-based metallic glasses(Co-Cr-Mo-C-B system).In addition,some of the bulk samples prepared with a diameter of 2 mm form bulk metallic glasses with a high compressive strength around 3.5 GPa.The mechanisms determining the stability of the supercooled liquid,as well as the paramagnetic and mechanical properties for the developed non-equiatomic HEMGs,are discussed. | Jeong Tae Kim Sung Hwan Hong Jin Man Park Jürgen Eckert Ki Buem Kim | 2020 | Journal of Materials Science & Technology2020，36，8： | 3 |
| 7 | Diabetic factors associated with gastrointestinal symptoms in patients with type 2 diabetes显示文摘AIM: To determine whether gastrointestinal (GI) symptoms are more frequent in type 2 diabetic patients and to examine which diabetic factors are associated with the symptoms. METHODS: Consecutive subjects with diabetes and age-/gender-matched normal controls were recruited for this study. GI symptoms were assessed using a structured questionnaire divided into two GI symptomcategories (upper and lower GI symptoms), and consisting of 11 individual symptoms. In the diabetic patient group, diabetic complications including peripheral neuropathy, nephropathy and retinopathy, glycosylated hemoglobin (HbA1c) level and diabetes duration were evaluated. RESULTS: Among the total 190 diabetic patients and 190 controls enrolled, 137 (72%) of the diabetic patients and 116 (62%) of the controls had GI symptoms. In the diabetic patient group, 83 (43%) had upper GI symptoms and 110 (58%) lower GI symptoms; in the control group, 59 (31%) had upper GI symptoms and 104 (55%) lower GI symptoms. This difference between the two groups was significant for only the upper GI symptoms (P = 0.02). Among the diabetic factors, the HbA1c level was the only independent risk factor for upper GI symptoms in the multiple logistic regression analysis (odds ratio = 2.01, 95% confidence interval: 1.02-3.95). CONCLUSION: Type 2 diabetes was associated with an increased prevalence of upper GI symptoms and these symptoms appeared to be independently linked to poor glycemic control, as measured by the HbA1c levels. | Jeong Hwan Kim Hyung Seok Park Soon Young Ko Sung Noh Hong In-Kyung Sung Chan Sub Shim Kee-Ho Song Dong-Lim Kim Sook Kyung Kim Jeeyoung Oh | 2010 | World Journal of Gastroenterology2010，16，14： | 3 |
| 8 | Prevalence and risk of colorectal neoplasms in asymptomatic, average-risk screenees 40 to 49 years of age显示文摘 | Sung Noh Hong Jeong Hwan Kim Won Hyeok Choe Hye Seung Han In Kyung Sung Hyung Seok Park Chan Sup Shim | 2010 | Gastrointestinal Endoscopy2010，，3： | 3 |
| 9 | Change in renal function after sodium phosphate preparation for screening colonoscopy显示文摘AIM:To investigate the changes in renal function at 12-24 mo in patients following sodium phosphate(NaP) preparation for screening colonoscopy.METHODS:We carried out a retrospective study on the results from patients who received health check-up services as part of an employer-provided wellness program performed between August 2006 and May 2008 and who were followed up for 12-24 mo.Prior to screening colonoscopy,224 patients underwent bowel cleansing with NaP(NaP group) and 113 patients with polyethylene glycol(PEG group).The control group comprised 672 age-matched patients.We compared the changes in the creatinine levels and the glomerular filtration rates(GFRs) from baseline to 12-24 mo between the NaP,PEG,and control groups using two-way repeated measured analysis of variance.In addition,multivariate linear regression analysis was performed to assess the risk factors for a decreased GFR.RESULTS:The baseline mean serum creatinine level in the NaP,PEG,and control groups was 1.12 ± 0.15,1.12 ± 0.16,and 1.12 ± 0.15 mg/dL,which increased to 1.15 ± 0.15,1.15 ± 0.18,and 1.15 ± 0.15 mg/dL,respectively,after 12-24 mo.The baseline mean GFR in the NaP,PEG,and control groups was 69.0 ± 7.7,68.9 ± 8.0,and 69.6 ± 6.7 mL/min per 1.73 m2,which decreased to 66.5 ± 7.8,66.5 ± 8.3,and 67.4 ± 6.4 mL/min per 1.73 m2,respectively,after 12-24 mo.The changes in serum creatinine levels and GFRs were not significantly between the NaP,PEG,and control groups(P = 0.992 and P = 0.233,respectively).Using multivariate linear regression analysis,only the baseline GFR was associated with the change in GFR(P < 0.001).Indeed,the bowel preparations were not associated with the change in GFR(P = 0.297).CONCLUSION:NaP bowel preparation in subjects with normal renal function was not associated with renal injury,and NaP can thus be used safely for screening colonoscopy. | Dong Choon Seol Sung Noh Hong Jeong Hwan Kim In Kyung Sung Hyung Seok Park Jung Hyun Lee Chan Sup Shim | 2010 | World Journal of Gastroenterology2010，16，16： | 2 |
| 10 | Growth of BaTiO_3-Ag hybrid composite films at room temperature by aerosol deposition显示文摘Barium titanate (BaTiO3) and silver (Ag) composite film with high dielectric constant was grown at room temperature by an aerosol deposition method.The dielectric constant increases by 0.5 times after adding Ag to the BaTiO3 matrix,compared with pure BaTiO3.The high dielectric constant can be attributed to the percolation effect of Ag inclusions in the BaTiO3 matrix.The Ag was present in the form of discrete layer in the BaTiO3 film.The dielectric properties of BaTiO3 Ag were discussed in detail taking into account the changes in microstructures. | Young Joon YOON Sung Hwan CHO Jihoon KIM Hyo Tae KIM Hong Koo BAIK Jong-Hee KIM | 2012 | 中国有色金属学会会刊:英文版2012，22，S3： | 2 |
| 11 | New antireflux self‐expandable metal stent for malignant lower biliary obstruction: In vitro and in vivo preliminary study显示文摘 | Dong Uk Kim Chang‐Il Kwon Dae Hwan Kang Kwang Hyun Ko Sung Pyo Hong | 2012 | Digestive Endoscopy2012，，1： | 2 |
| 12 | How Can We Predict the Presence of Missed Synchronous Lesions After Endoscopic Submucosal Dissection for Early Gastric Cancers or Gastric Adenomas?显示文摘 | Jun Hwan Yoo Sung Jae Shin Kee Myung Lee Jae Myoung Choi Jeong Ook Wi Dong Hoon Kim Sun Gyo Lim Jae Chul Hwang Jae Youn Cheong Byung Moo Yoo Kwang Jae Lee Jin Hong Kim Sung Won Cho | 2013 | Journal of Clinical Gastroenterology2013，，2： | 2 |
| 13 | Prevalence and Clinical Features of Coagulation Syndrome After Endoscopic Submucosal Dissection for Colorectal Neoplasms显示文摘 | Mi Jin Hong Jeong Hwan Kim Sun-Young Lee In-Kyung Sung Hyung Seok Park Chan Sup Shim | 2015 | Digestive Diseases and Sciences2015，，1： | 2 |
| 14 | Spreading epidural hematoma and deep subcutaneous edema: indirect MRI signs of posterior ligamentous complex injury in thoracolumbar burst fractures显示文摘 | Na Ra Kim Sung Hwan Hong Ja-Young Choi Bong-Soon Chang Joon Woo Lee Jae Sung Myung Sung Gyu Moon Heung Sik Kang | 2010 | Skeletal Radiology2010，，8： | 1 |
| 15 | Effect of undercooling of austenite on strain induced ferrite transformation beharior显示文摘 | Seung Chan HONG Sung Hwan LIM Kyung Jong LEE | 2003 | ISU International2003，43，3： | 1 |
| 16 | Risk factors for perforations associated with endoscopic submucosal dissection in gastric lesions: emphasis on perforation type显示文摘 | Jun Hwan Yoo Sung Jae Shin Kee Myung Lee Jae Myoung Choi Jeong Ook Wi Dong Hoon Kim Sun Gyo Lim Jae Chul Hwang Jae Youn Cheong Byung Moo Yoo Kwang Jae Lee Jin Hong Kim Sung Won Cho | 2012 | Surgical Endoscopy2012，，9： | 1 |
| 17 | Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation<!-- CT-based vessel-guided target volume delineation -->显示文摘 | Hong In Yoon Jee Suk Chang Joon Seok Lim Sung Hoon Noh Woo Jin Hyung Ji Yeong An Yong Chan Lee Sun Young Rha Kyung Hwan Kim Woong Sub Koom | 2013 | Radiotherapy and Oncology2013，，： | 1 |
| 18 | Relationship Between Prostatic Urethral Angle and Urinary Flow Rate: Its Implication in Benign Prostatic Hyperplasia Pathogenesis显示文摘 | Kang Su Cho Joo Han Kim Dong Jun Kim Young Deuk Choi Jang Hwan Kim Sung Joon Hong | 2008 | Urology2008，，5： | 1 |
| 19 | The overlooked cause of benign prostatic hyperplasia: prostatic urethral angulation显示文摘 | Kang Su Cho Joohan Kim Young Deuk Choi Jang Hwan Kim Sung Joon Hong | 2007 | Medical Hypotheses2007，，3： | 1 |
| 20 | The 5-year functional outcomes after radical prostatectomy: a real-life experience in Korea显示文摘我们关于可勃起的功能和尿克制调查了功能的结果直到在朝鲜的人的一个队跟随激进的前列腺切除术(RP ) 的 5 年。我们回顾地分析了为临床上局部性的前列腺癌症收到了开的 uni- 或双边的神经圆材 RP 并且被跟随在上面的 85 个朝鲜的人的 clinicopathologic 数据为至少 5 年手术后地。从医药记录,病人关于在在 RP 以后的基线和手术后的后续行动的尿、可勃起的功能的地位被估计。在在 RP 以后的 24 和 60 个月,题目大陆(使用的没有垫) 的比例是 89.4% 和 97.6% ,分别地(P = 0.007 ) 。排除题目(n = 24 ) 外科手术前地报导了有严重可勃起的机能障碍或缺乏相关信息,能够不管可勃起的帮助用法有阴道交际的题目的比例在从 RP 的 24 和 60 个月是 47.5% 和 37.7% ,分别地(P = 0.022 ) 。病人在外科的年龄(P = 0.047 ) 并且抢救放射治疗(P = 0.026 ) 被观察是在 multivariate 分析从 RP 在 60 个月有为交际足够的勃起的重要预言者。当病人关于在从 RP 的 2 年的尿克制的手术后的地位通常在 5 年点被维持或改善时,我们的结果显示出那,可勃起的功能被观察到显著地从 2 年衰退了到 5 年后面的 RP。在可勃起的功能追随者 RP 的如此的衰落可能在在在手术后的后续期间收到了抢救治疗的外科或那些相对更老的男人之中是更重要的。 | Sung Kyu Hong Seung Hwan Doo Dae Sung Kim Won Ki Lee Hong Zoo Park Ji Hyun Park Seong Jin Jeong Cheol Yong Yoon Seok-Soo Byun Sang Eun Lee | 2010 | Asian Journal of Andrology2010，12，6： | 1 |
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