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| 1 | 乳腺癌组织中TP和TS及DPD mRNA表达与预后的关系显示文摘目的 探讨乳腺癌组织中胸苷酸化酶 (TP)、胸苷酸合成酶 (TS)和二氢嘧啶脱氢酶(DPD)mRNA表达水平及其与预后的关系。方法 采用real time定量PCR技术检测经过微选的 9例正常乳腺组织和 86例乳腺癌组织TP、TS和DPD的mRNA表达水平。结果 肿瘤组织中TP、TS和DPDmRNA表达水平中位数分别为 16 .5 4 ,0 .38和 2 .74 ,正常乳腺组织分别为 11.75 ,0 .2 5和 8.33,差异均无显著性 (P >0 .0 5 )。除年龄与DPD表达呈负相关外 ,TP、TS和DPDmRNA表达与肿瘤体积、淋巴结转移、组织学分级、临床分期均无相关性。TP、DPD高表达组和低表达组之间 ,无瘤生存期和总生存期差异均无显著性。TS高表达组和低表达组无瘤生存期差异无显著性 (P =0 .0 6 9) ;平均总生存期分别为 5 9.0 0和 70 .30个月 ,差异有显著性 (P =0 .0 4 96 )。结论 仅检测TSmRNA对判断乳腺癌预后有参考价值 ,同时检测TP、TS和DPD具有更好的预测价值。 | 李惠翔 Suo ZH 张云汉 Bjrn Risberg Mats G Karlsson Jahn M Nesland | 2004 | 中华肿瘤杂志2004，26，11： | 9 |
| 2 | Corrosion cracking prediction updating of deteriorating RC structures using inspection information显示文摘 | Suo Q H Stewart M G | 2009 | Reliability Engineering&System Safety2009，94，8： | 1 |
| 3 | Nonequilibrium thermodynamics of dielectric elastomers显示文摘 | ZHAOX H KOH S J A SUO Z G | | International Journal of Applied Mechanics0，3，： | 1 |
| 4 | Microstructure and mechanical properties of bulk Mg-Zn-Ca amorphous alloys and amorphous matrix composites显示文摘 | LI Q F WENG H R SUO Z Y REN Y L YUAN X G QIU K Q | 2008 | Mater Sci Eng A2008，487，： | 1 |
| 5 | Method to analyze electromechanical stability of dielectric elastomers显示文摘 | ZHAO X H SUO Z G | | Applied Physics Letters0，1，06： | 1 |
| 6 | Mixed mode cracking in layered materials显示文摘 | Hutchinson J W Suo Z G | 1992 | Advances in Applied Mechanics1992，29，： | 1 |
| 7 | Corrosion Cracking Prediction Updating of Deteriorating RC Structures Using Inspection Information 显示文摘 | SUO Q H STEWART M G | 2009 | Reliability Engineering & System Safety2009，94，8： | 1 |
| 8 | Delamination of stiff islands patterned on stretchable substrates 显示文摘 | LU N S YOON J SUO Z G | 2007 | International Jour- nal of Materials Research2007，98，8： | 1 |
| 9 | First-principles considerations in the design of Pd-alloy catalysts for oxygen reduction显示文摘 | SUO Y G ZHUANG L LU J | 2007 | Angewandte Chemie International Edition2007，46，16： | 1 |
| 10 | Deformation mechanisms in nacre显示文摘 | Wang R Z Suo Z Evans A G | | 0，，09： | 1 |
| 11 | Posttranscriptional control of BNP gene expression in angiotensin Ⅱ-induced hypertension显示文摘 | Suo M Hautala N Foldes G | 2002 | Hypertension2002，39，3： | 1 |
| 12 | Interface crack between two elastic layers 显示文摘 | Suo Z G Hutchinson J W | 1990 | International Journal of Fracture1990，43，1： | 1 |
| 13 | Singularities interacting with interfaces andcracks显示文摘 | SUO Z G | 1989 | International Journal of Solids and Structures1989，25，10： | 1 |
| 14 | Oct4pseudogenes are tran-scribed in cancers显示文摘 | Suo G Han J Wang X | 2005 | Biochem Biophys Res Commun2005，337，4： | 1 |
| 15 | Stability of solidswith interfaces显示文摘 | SUO Z G ORTIZ M NEEDLEMAN A | 1992 | Journal of the Mechanics and Physicsof Solids1992，40，3： | 1 |
| 16 | A compositional and dynamic model for face aging 显示文摘 | Suo J L Zhu S C Shan Sh G | 2010 | IEEE Transactions on Pattern Analysis and Machine Intelligence2010，32，3： | 1 |
| 17 | Deformation mechanisms in nacre 显示文摘 | Wang R Z Suo Z Evans A G Yao N Aksay I A | 2001 | Journal of Materials Research2001，16，9： | 1 |
| 18 | Fractal analysis of veins in Permian carbonate rocks in Lingtanchang anticline, southern Siehuan Basin, western China显示文摘 | Deng B Liu S G Suo Yang | 2014 | Geofluids2014，14，： | 1 |
| 19 | Interface crack between two elastic layers显示文摘 | Suo Z G Hutchinson J W | 1990 | International Journal of Fracture1990，43，1： | 1 |
| 20 | Nonlinear oscillation of a di- electric elastomer balloon 显示文摘 | ZHU J CAI S Q SUO Z G | 2010 | Polymer International2010，59，： | 1 |
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