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| 1 | 欧洲新生儿呼吸窘迫综合征防治指南-2010版显示文摘呼吸窘迫综合征(RDS)是由于肺表面活性物质(PS)缺乏及肺结构发育不成熟所致,多见于早产儿,自然病程为生后当时或很快发病,并在生后2d内进行性恶化,如不及时治疗,因进行性缺氧和呼吸衰竭而死亡,存活者,在生后2—4d病情开始改善。胎龄越小,RDS发生率越高,2006年EuroNeoStat的数据显示:胎龄23~25周的早产儿RDS发生率为91%, | Sweet DG Carnielli V Greisen G Hallman M Ozek E Plavka R Saugstad OD Simeoni U Speer CP Halliday HL 袁琳(翻译) 陈超(审校) | 2011 | 中华儿科杂志2011，49，1： | 137 |
| 2 | 欧洲早产儿呼吸窘迫综合征防治共识指南(2013版)显示文摘本次指南更新包括了自2010年以来Cochrane系统评价和医学文献中的最新证据,并采纳了一种新的证据评估分级系统(GRADE)。以往关于早期肺表面活性物质和持续气道正压通气治疗的推荐目前拥有了更坚定的循证依据。对产房复苏、稳定生命体征等内容进行了较大扩充。生命体征稳定后的氧疗目前仍存在一定的争议,但是在获得更多的证据之前,血氧饱和度的目标范围不应低于90%,支持治疗对于超早早产儿仍然极为重要。指南对其他注意事项进行了缩减。 | Sweet D Carnielli V Greisen G Hallman M Ozek E Plavka R Saugstad OD Simeoni U Speer CP Halliday HL 王敏婕 袁琳 陈超 | 2014 | 中华儿科杂志2014，52，10： | 34 |
| 3 | 欧洲新生儿呼吸窘迫综合征防治共识显示文摘呼吸窘迫综合征(RDS)是由于肺表面活性物质(PS)缺乏及肺结构发育不成熟所致,多见于早产儿,自然病程为出生当时或生后很快发病,并在生后2d内进行性恶化,如不及时治疗,因进行性缺氧和呼吸衰竭而死亡。存活者出生后2—4d病情开始改善。RDS临床表现早期出现呼吸窘迫如紫绀、呻吟、吸凹和呼吸急促,然后进一步发展为呼吸衰竭,血气分析结果可提示呼吸衰竭的严重性。胸部X线典型的毛玻璃样改变和支气管充气征可以确诊。Vermont Oxford新生儿协作网对RDS的定义为: | Sweet D Bevilacqua G Carnielli V Greisen G Plavka R Didrik Saugstad O Simeoni U Speer CP Valls-I-Soler A Halliday H 袁琳(译) 陈超(译) 杜立中(校) | 2008 | 中华儿科杂志2008，46，1： | 17 |
| 4 | Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury. | Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell | 2012 | World Journal of Gastroenterology2012，18，15： | 3 |
| 5 | Determingtion of Sulfon-amide Residues in the Tissues of Food Animals Using Automated Precolumn Derivatization and Liquid Chromatography with Fluorescence Detection显示文摘 | Salisburk C D C Sweet J C Munro R | 2004 | J AOAC Int2004，87，5： | 1 |
| 6 | Tributyltin in environmental samples from the Former Derecktor Shipyard, Coddington Cove, Newport RI显示文摘 | Wade T L Sweet S T Quinn J G Cairns R W King J W | 2004 | Environmental Pollution2004，129，2： | 1 |
| 7 | Determination of the sensitivity and specificity of sibship calculations using AmpF STR Profiler Plus显示文摘 | Gaytmenn R Hildebrand DP Sweet D | 2002 | Int J Legal Med2002，116，3： | 1 |
| 8 | Some chemical reactions of 3, 9-diehloro-2,4,8,10-tetraoxa-3,9-diphosphaspiro undeeane3,9-dioxide 显示文摘 | Ratz R Sweeting O J | 1963 | J Org Chem1963，28，3： | 1 |
| 9 | Regulated expression at high copy number allows production of a growth inhibitory oncogene product in drosophila schneider cells显示文摘 | JOHANSEN H VANDER S A SWEET R | 1989 | Genes and Development1989，3，： | 1 |
| 10 | Dimensions of positive symptoms in late versus early onset psychosis显示文摘 | Mason O Stott J Sweeting R | 2013 | Int Psychogeriatr2013，25，2： | 1 |
| 11 | Geology and geochemistry of gas hydrated central Gulf of Mexico continental slope显示文摘 | Sasses R Sweet S T Milkov A V | 1999 | Gulf Coast Association of Geological Societies Transactions1999，49，： | 1 |
| 12 | Flame-excited luminescence in the oxides Ta2OsNb2Os, TiO2, ZnO, and SnO2显示文摘 | PROVENZANO P L JINDAL G R SWEET J a | 2001 | J Lumin2001，92，4： | 1 |
| 13 | The vacuolating virus,SV40显示文摘 | Sweet B H Hilleman M R | 1960 | Proc Soc Exp Biol Med1960，105，： | 1 |
| 14 | The extraosseous and intraosseous arterialanatomy of the adult elbow显示文摘 | YAMAGUCHI K SWEET FA BINDRA R | 1997 | J Bone Joint Surg (Am)1997，79，11： | 1 |
| 15 | Middle juras-sic to lower cretaceous paleoclimate of sverdrup basin, Cana-dian arctic archipelago inferred from the palynostratigraphy显示文摘 | Galloway J M Sweet A R Swindles G T | 2013 | Marine & Petroleum Geology2013，44，3： | 1 |
| 16 | Mechanism of organic anion transport across the apical membrane of choroid plexus显示文摘 | Pritchard JB Sweet DH Miller DS Walden R | 1999 | J Biol Chem1999，274，33： | 1 |
| 17 | A cyclic reduction algorithm for solving block tridiagonal systems of arbitrary dimensions 显示文摘 | Sweet R | 1977 | SIAM J on Numer Anal1977，14，4： | 1 |
| 18 | The effects of starvation and food intake on hepatic thyroxine-monodeidinase activity in the rainbow trout, Oncorhynchus mykiss 显示文摘 | Sweeting R M Eales J G | 1992 | Can J Zool1992，70，： | 1 |
| 19 | Temporal trends in gas-phase concentrations of chlorinated pesticides measured at the shores of the Great Lakes显示文摘 | Cortes D R Basu I Sweet C W | 1998 | Environmental Science & Technology1998，32，13： | 1 |
| 20 | Determination of the sensitivity and specificity of sibship calculations using AmpF1STR Profiler Plus 显示文摘 | Gaytmenn R Hildebrand DP Sweet D | 2002 | Int J Legal Med2002，116，3： | 1 |
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