|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association of genetic variants with diabetic nephropathy显示文摘Diabetic nephropathy accounts for the most serious microvascular complication of diabetes mellitus. It is suggested that the prevalence of diabetic nephropathy will continue to increase in future posing a major challenge to the healthcare system resulting in increased morbidity and mortality. It occurs as a result of interaction between both genetic and environmental factors in individuals with both type 1 and type 2 diabetes. Genetic susceptibility has been proposed as an important factor for the development and progression of diabetic nephropathy, and various research efforts are being executed worldwide to identify the susceptibility gene for diabetic nephropathy. Numerous single nucleotide polymorphisms have been found in various genes giving rise to various gene variants which have been found to play a major role in genetic susceptibility to diabetic nephropathy. The risk of developing diabetic nephropathy is increased several times by inheriting risk alleles at susceptibility loci of various genes like ACE, IL, TNF-α, COL4A1, e NOS, SOD2, APOE, GLUT, etc. The identification of these genetic variants at a biomarker level could thus, allow the detection of those individuals at high risk for diabetic nephropathy which could thus help in the treatment, diagnosis and early prevention of the disease. The present review discusses about the various gene variants found till date to be associated with diabetic nephropathy. | Saliha Rizvi Syed Tasleem Raza Farzana Mahdi | 2014 | World Journal of Diabetes2014，5，6： | 20 |
| 2 | Nutritional support in chronic liver disease and cirrhotics显示文摘The liver is a major organ and an essential componentin maintaining an appropriate nutritional status in healthy individuals through metabolism of protein, carbohydrates, and fat. In individuals with chronic liver disease(CLD), along with a number of other essen-tial functions that the liver serves, its role in nutrition maintenance is severely impaired. Common causes of CLD include hepatitis C, alcoholic liver disease, and non-alcoholic liver disease. Amongst this population, the most common manifestation of impaired nutritional maintenance is protein-calorie malnutrition. Aside from inherent abnormalities in metabolism, such as malab-sorption and maldigestion, CLD can be associated with anorexia as well as increased metabolic requirements, all of which contribute to a state of malnutrition. Given the systemic implications and impact on prognosis of malnutrition, proper nutritional assessment is essential and can be achieved through a thorough history and physical, as well as biochemical investigations and anthropometry as needed. Following an appropriate assessment of a patient's nutritional status, an approach to management can be decided upon and is based on the extent of malnutrition which directly reflects the severity of disease. Management options can be grossly separated into enteral and parenteral nutrition. The former is usually sufficient in the form of oral supplements in less severe cases of malnutrition, but as the CLD worsens, parenteral nutrition becomes necessary. With appropriate assessment and early intervention, many of the complications of CLD can be avoided, and ultimately better outcomes can be achieved. | Ravi Shergill Wajahat Syed Syed Ali Rizvi Ikjot Singh | 2018 | World Journal of Hepatology2018，10，10： | 17 |
| 3 | Approach to pseudomyxoma peritonei显示文摘Pseudomyxoma peritonei(PMP) is a mucinous tumour of the appendix that spreads into the peritoneal cavity in the form of gelatinous deposits. The incidence of PMP is believed to be approximately 1-3 out of a million per year. Nonetheless, due to its indolent nature, it is usually discovered at an advanced stage and severely impacts quality of life. Curative treatment for PMP is complete cytoreductive surgery(CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC). An extensive literature review was conducted searching EMBASE, MEDLINE, Pub Med, and Google Scholar databases for PMP in aims to delineate a clinical approach to diagnosis and treatment. Literature was limited to the years 2007-2018. We found the 5-year overall survival with CRS and HIPEC estimated to be between 23%-82% and rates of major complications as high as 24%. Therefore, it is important to appropriately stage and select patients that should undergo CRS with HIPEC. Modalities like MDCT radiological scores have been shown to have sensitivity and specificity of 94% and 81%, respectively, in being able to predict resectability and survival. Despite treatment, the disease often recurs. Tumor markers have significant potential for establishing prognosis preoperatively, and this paper will review the most recent evidence in support of them. | Syed Ali Rizvi Wajahat Syed Ravi Shergill | 2018 | World Journal of Gastrointestinal Surgery2018，10，5： | 15 |
| 4 | Association of gene variants with susceptibility to type 2 diabetes among Omanis显示文摘AIM:To investigate the association of 10 known common gene variants with susceptibility to type 2diabetes mellitus(T2D)among Omanis.METHODS:Using case-control design,a total of992 diabetic patients and 294 normoglycemic Omani Arabs were genotyped,by an allelic discrimination assay-by-design TaqMan method on fast real time polymerase chain reaction system,for the following gene variants:KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398),CDKN2A/B(rs10811661),FTO(rs9939609 and rs8050136),IGF2BP2(rs4402960),SLC30A8(rs13266634)CAPN10(rs3792267)and HHEX(rs1111875).T2D patients were recruited from the Diabetes Clinic(n=243)and inpatients(n=749)at Sultan Qaboos Univesity Hospital(SQUH),Muscat,Oman.Adult control participants(n=294)were volunteers from the community and from those visiting Family Medicine Clinic at SQU,for regular medical checkup.The difficulty in recruiting Omani participants with no family history of diabetes was the main reason behind the small number of control participants in this study.Almost all volunteers questioned had a relativewith diabetes mellitus.Inspite of the small number of normoglycemic controls in this study,this sample was sufficient for detection of genes and loci for common alleles influencing T2D with an odds ratio of≥1.3reaching at least 80%power.Data was collected from June 2010 to February 2012.RESULTS:Using binary logistic regression analysis,four gene variants showed significant association with T2D risk:KCNJ11(rs5219,P=5.8×10^(-6),OR=1.74),TCF7L2(rs7903146,P=0.001,OR=1.46),CDKAL1(rs10946398,P=0.002,OR=1.44)and CDKN2A/B(rs10811661,P=0.020,OR=1.40).The fixation index analysis of these four gene variants indicated significant genetic differentiation between diabetics and controls{[KCNJ11(rs5219),P<0.001],[TCF7L2(rs7903146),P<0.001],[CDKAL1(rs10946398),P<0.05],[CDKN2A/B(rs10811661),P<0.05]}.The highest genotype variation%between diabetics and controls was found at KCNJ11(2.07%)and TCF7L2(1.62%).This study was not able to detect an association of T2D risk with gene variants of IGF2BP2(rs4402960),SLC30A8(rs13266634),CAPN10(rs3792267)and HHEX(rs1111875).Moreover,no association was found between FTO gene variants(rs9939609 and rs8050136)and T2D risk.However,T2D risk was found to be significantly associated with obesity(P=0.002,OR=2.22);and with the Waist-to-Hip ratio(n=532,P=1.9×10^(-7),OR=2.4),[among males(n=234,P=1.2×10^(-4),OR=2.0)and females(n=298,P=0.001,OR=6.3)].CONCLUSION:Results confirmed the association of KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398)and CDKN2A/B(rs10811661)gene variants with susceptibility to T2D among Omani Arabs. | Sawsan Al-Sinani Nicolas Woodhouse Ali Al-Mamari Omaima Al-Shafie Mohammed Al-Shafaee Said Al-Yahyaee Mohammed Hassan Deepali Jaju Khamis Al-Hashmi Mohammed Al-Abri Khalid Al-Rassadi Syed Rizvi Yengo Loic Philippe Froguel Riad Bayoumi | 2015 | World Journal of Diabetes2015，6，2： | 3 |
| 5 | Effects of Ferulago angulata Extract on Serum Lipids and Lipid Peroxidation显示文摘 | Mahmoud Rafieian-kopaei Najmeh Shahinfard Hojjat Rouhi-Boroujeni Mojgan Gharipour Pariya Darvishzadeh-Boroujeni Syed Ibrahim Rizvi | 2014 | Evidence-Based Complementary and Alternative Medicine2014，，： | 2 |
| 6 | A modular clutter rejection technique for FLIR imagery using region-based principal component analysis显示文摘 | Syed A Rizvi Nasser M Nasrabadi | 2002 | Pattern Recognition2002，35，： | 2 |
| 7 | Altered Redox Status in Erythrocytes From Hypertensive Subjects: Effect of(-)Epicatechin显示文摘Hypertension is a major problem worldwide. There is much evidence to suggest that reactive oxygen species (ROS) radical may play a role in the development of organ damage associated with cardiovascular disease and hypertension. (-)Epicatechin, a member of tea catechins belonging to flavonoid group, is known to be a potent anti-oxidant. The study has been undertaken to evaluate the effect of (-)epicatechin on markers of oxidative stress: reduced glutathione (GSH) and membrane sulfhydryl (-SH) groups in erythrocytes from hypertensive patients. The effect of (-)epicatechin was also compared with a known anti-oxidant L-ascorbic acid. The erythrocyte intracellular GSH content and membrane -SH group content were significantly (P<0.01) decreased in hypertensive subjects. In vitro incubation with (-)epicatechin caused an increase in GSH and -SH content, the effect was more pronounced in hypertensive erythrocytes. Similar results were obtained with L-ascorbic acid. The observed decrease in the level of GSH and -SH groups in hypertension is an indicator of oxidative stress condition. Observation of an increase in red cell GSH content and the protection of membrane -SH group oxidation by (-)epicatechin in hypertensive subjects is a convincing reason to suggest that high dietary intake of foods rich in catechins may help to reduce oxidative stress and concomitant free radical damage in hypertensive patients. | SYED IBRAHIM RIZVI NAVNEET KUMAR | 2005 | 生物化学与生物物理进展2005，32，3： | 2 |
| 8 | The feret evaluation methodology for face-recognition algorithms 显示文摘 | P Jonathon Phillips Hyeonjoon Moon Syed A Rizvi Patrick J Rauss | 2000 | Pattern Analysis and Machine Intelligence IEEE Transactions on2000，22，10： | 1 |
| 9 | In vitro antioxidant and in vivo hepatoprotective activity of leave extract of Raphanus sativus in rats using CC14 model 显示文摘 | Syed S N Rizvi W Kumar A A | 2014 | Afr J Tradit Complement Altern Med2014，11，3： | 1 |
| 10 | Evaluation and improvement of CDS-based topology control for wireless sensor networks显示文摘 | Hassaan Khaliq Qureshi Sajjad Rizvi Muhammad Saleem Syed Ali Khayam Veselin Rakocevic Muttukrishnan Rajarajan | 2013 | Wireless Networks2013，，1： | 1 |
| 11 | Thyroid hormone levels in hepatitis B显示文摘 | Rizvi SJ Syed S | 1992 | J Pak Med Assoc1992，42，3： | 1 |
| 12 | Oviposition preference and larval performance of Epiphyas postvittana (Lepidoptera: Tortricidae) on Botrytis cinerea (Helotiales: Sclerotiniaceae) infected berries of Vitis vinifera (Vitales: Vitaceae)显示文摘在这份报纸,我们在为因此有益于后代性能的 oviposition 选择大多数适当的地点测试了怀孕 Epiphyas postvittana 的行为。我们的假设在 Jaenikes 偏爱表演假设上被造(也叫作 “mother-knows-the-best”假设) 。测试这,我们使用了交往的 Epiphyas postvittana,它的主人 Vitis vinifera,和病原的微生物 Botrytis cinerea 系统。E 的人口。postvittana 和 B。cinerea 经常在 V 上并发地存在。在澳大利西亚和他们的相互作用和相互的影响的 vinifera 当前正在被探索,尽管建议目前是在 E 之间的关系。postvittana 和 B。cinerea 是 mutualistic。我们从 B 测试了 volatiles 的效果。感染 cinerea 的果浆和 uninfected (控制) V 的果浆。E 的 oviposition 行为上的 vinifera。postvittana。我们也描绘了 B 的效果。V 的果浆上的 cinerea 感染。E 的生长和发展上的 vinifera。postvittana。与偏爱表演假设相反, oviposition 选择由怀孕 E 做了。postvittana 没导致最好的后代幸存,开发,和性能。为由 E 的 oviposition 的偏爱。postvittana 被嗅觉、触觉的暗示强烈影响。她在 B 上生了更少鸡蛋。与 V 的 uninfected 果浆相比的感染 cinerea 的果浆。vinifera。E 的幼虫。postvittana 没显示出偏爱到 V 的 uninfected 果浆。vinifera。在 B 上喂的幼虫。V 的感染 cinerea 的果浆。显示出更大的幸存率的 vinifera,化蛹的更短的时间,更大的蛹的质量,并且在成为成年人以后,他们比被使能在 uninfected 上喂果浆的幼虫放了鸡蛋的更多的数字。E 的幼虫。postvittana 运输 B 的 conidia。cinerea 并且把灰模子的疾病传给 V 的 uninfected 果浆。vinifera。 | Syed Z. M. Rizvi Anantanarayanan Raman Warwick M. Wheatley Geoffrey Cook | 2016 | Insect Science2016，23，2： | 1 |
| 13 | Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery显示文摘 | Gavin J. Murphy Barnaby C. Reeves Chris A. Rogers Syed I.A. Rizvi Lucy Culliford Gianni D. Angelini | 2007 | Circulation2007，，22： | 1 |
| 14 | The FERET evaluation methodology for face-recognition algorithms显示文摘 | PHILLIPS P J SYED H M RIZVI A | 2000 | IEEE Transactions on Pattern Analysis and Machine Intelligence2000，22，10： | 1 |
| 15 | Neural networks for automatic target recognition显示文摘 | Syed A Rizvi Nass MN asrabadi | 1995 | Information Fusion1995，，8： | 1 |
| 16 | Current understanding of dietary polyphenols and their role in health and diseases显示文摘 | Kanti Bhooshan Pandey Syed Ibrahim Rizvi | 2009 | Current Nutrition & Food Science2009，，5： | 1 |
| 17 | Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery显示文摘 | Gavin J. Murphy Barnaby C. Reeves Chris A. Rogers Syed I.A. Rizvi Lucy Culliford Gianni D. Angelini | 2007 | Circulation2007，，22： | 1 |
| 18 | A1: An energy efficient topology control algorithm for connected area coverage in wireless sensor networks显示文摘 | Sajjad Rizvi Hassaan Khaliq Qureshi Syed Ali Khayam Veselin Rakocevic Muttukrishnan Rajarajan | 2011 | Journal of Network and Computer Applications2011，，2： | 1 |
| 19 | Biodegradable and functionally superi-or starch-polyester nanocomposites from reactive extrusion显示文摘 | KALAMBUR S RIZVI SYED S H | 2005 | Journal of Applied Polymer Science2005，96，： | 1 |
| 20 | Formu- lation and evaluation of drug - loaded targeted magnetic microspheres for cancer therapy 显示文摘 | Gerald G Enriquez Syed AA Rizvi Martin J D' Souza | 2013 | J Nanomedicine2013，8，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员