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3篇 您的检索式:作者名="Syed Sattar"
    题名 作者 年代 出处 被引量
1Fate of Cryptosporidium oecysts,Giardia cysts,and microbial indicators during wastewater treatment and anaerobic sludge digestion显示文摘Christian Chauret Susan Springthorpe Syed Sattar 1999Canadian Journal of Microbiology1999,45,:1
2Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis显示文摘Non-alcoholic fatty liver disease(NAFLD),is a disease spectrum characterized by fat accumulation in hepatocytes presenting as hepatic steatosis to advance disease with active hepatic inflammation,known as nonalcoholic steatohepatitis.Chronic steatohepatitis will lead to progressive hepatic fibrosis causing cirrhosis and increased risk for developing hepatocellular carcinoma(HCC).Fatty liver disease prevalence has increased at alarming rates alongside obesity,diabetes and metabolic syndrome to become the second most common cause of cirrhosis after alcohol related liver disease worldwide.Given this rise in prevalence,it is becoming increasingly more important to find non-invasive methods to diagnose disease early and stage hepatic fibrosis.Providing clinicians with the tools to diagnose and treat the full spectrum of NAFLD will help prevent known complications such as cirrhosis and HCC and improve quality of life for the patients suffering from this disease.This article discusses the utility of current noninvasive liver function testing in the clinical progression of fatty liver disease along with the imaging modalities that are available.Additionally,we summarize available treatment options including targeted medical therapy through four different pathways,surgical or endoscopic intervention.Tasur Kumar Seen Muntazir Sayed Muhammad Bilal Jonathan Vincent Reyes Priyanka Bhandari Vennis Lourdusamy Ahmed Al-khazraji Umer Syed Yasar Sattar Raghav Bansal 2021World Journal of Gastroenterology2021,27,23:1
3Cryptosporidium parvum oocyst directed assembly of gold nanoparticles and graphene oxide显示文摘Understanding the interactions between inorganic nanomaterials and biological species is an important topic for surface and environmental chemistry. In this work, we systematically studied the oocysts of Cryptosporidium pa r v u m as a model protozoan parasite and its interaction with gold nanoparticles (AuNPs) and graphene oxide (GO). The as-prepared citrate-capped AuNPs adsorb strongly on the oocysts leading to a vivid color change. The adsorption of the AuNPs was confirmed by transmission electron microscopy. Heat treatment fully inhibited the color change, indicating a large change of surface chemistry of the oocysts that can be probed by the AuNPs. Adding proteases such as trypsin and proteinase K partially inhibited the color change. DNA-capped AuNPs, on the other hand, could not be adsorbed by the oocysts. GO was found to wrap around the oocysts forming a conformal shell reflecting the shape of the oocysts. Both citratecapped AuNPs and GO compromised the membrane integrity of the oocysts as indicated by the propidium iodide staining experiment, and they may be potentially used for inactivating the oocysts. This is the first example of using nanomaterials to probe the surface of the oocysts, and it suggests the possibility of using such organisms to template the assembly of nanomaterials.Sona Jain Zhicheng Huang Brent R. Dixon Syed Sattar Juewen Liu 2019Frontiers of Chemical Science and Engineering2019,13,3:0
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