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| 1 | Reversed-phase fused-core HPLC modeling of peptides显示文摘Different fused-core stationary phase chemistries(C18,Amide,Phenyl-hexyl and Peptide ES-C18) were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition(ACN or MeOH as organic modifier;formic acid or acetic acid,as acidifying component) on the column selectivity,peak shape and overall chromatographic performance were evaluated.The RP-amide column,combined with a formic acid-acetonitrile based gradient system,performed as best.A peptide reversed-phase retention model is proposed,consisting of 5 variables:log SumAA,log Sv,clog P,log nHDon and log nHAcc.Quantitative structure-retention relationship(QSRR) models were constructed for 16 different chromatographic systems.The accuracy of this peptide retention model was demonstrated by the comparison between predicted and experimentally obtained retention times,explaining on average 86% of the variability.Moreover,using an external set of 5 validation peptides,the predictive power of the model was also demonstrated.This peptide retention model includes the novel in-silico calculated amino acid descriptor,AA,which was calculated from log P,3D-MoRSE,RDF and WHIM descriptors. | Matthias D'Hondt Bert Gevaert Sofie Stalmans Sylvia Van Dorpe Evelien Wynendaele Kathelijne Peremans Christian Burvenich Bart De Spiegeleer | 2013 | Journal of Pharmaceutical Analysis2013，3，2： | 3 |
| 2 | Mycorrhizae differentially alter growth,physiology,and competitive ability of an invasive shrub显示文摘 | Bray S R Kitajima K Sylvia D M | 2003 | Ecol Appl2003，13，3： | 2 |
| 3 | Methylcyclopropene: A review 显示文摘 | Sylvia M B John M D | 2003 | Postharvest Biology and Technology2003，28，： | 1 |
| 4 | The Sources, Fate, and Toxicity of Chemical Warfare Agent Degradation Products 显示文摘 | Nancy Munro Sylvia S TalmageGuy D | 1999 | Environmental Health Perspectives1999，107，12： | 1 |
| 5 | Variation in the rDNA ITS of ectomycorrhizal fungi显示文摘 | Farmer D J Sylvia D M | 1998 | Mycol Res1998，102，7： | 1 |
| 6 | Diversity of rotavirus strains circulating in Northern Brazil after introduction of a rotavirus vaccine: High prevalence of G3P[6] genotype显示文摘 | Luana da Silva Soares Sylvia de Fátima dos Santos Guerra Alessilva do Socorro Lima de Oliveira Fabiola da Silva dos Santos Euzeni Maria de Fátima Costa de Menezes Joana d’Arc Pereira Mascarenhas Alexandre C. Linhares | 2014 | Virol2014，，6： | 1 |
| 7 | Variation in the rDNA ITS of eetomyeorrhizal fungi显示文摘 | FARMER D J Sylvia D M | 1998 | Myeol Res1998，102，7： | 1 |
| 8 | The complete mitochondrial DNA sequence of the Atlantic salmon, Salmo sala 显示文摘 | Carolyn D Hurst A Sylvia E | 1999 | Gene1999，239，： | 1 |
| 9 | Potentiometric and fiberoptic sensors for pH based on an electropolymerized cobaltporphyrin显示文摘 | Timothy L B John R A Sylvia D | 1993 | Analytical Chemistry1993，65，15： | 1 |
| 10 | Interactions among root-inhabiting fungi and their implications for biological control of root pathogens显示文摘 | Sylvia D M Chellemi D O | | 0，，： | 1 |
| 11 | Sodium induces simultaneous changes in eytosolic calcium and pH in salt-tolerant quince protoplasts 显示文摘 | Cladio D Sylvia L | 2009 | Journal of Plant Physiology2009，166，16： | 1 |
| 12 | Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock显示文摘 | ANDREW G D RACHEL A SYLVIA A | 1993 | Infection and Immunity1993，61，11： | 1 |
| 13 | Depositional and diage- netic controls on the reservoir quality of lower cretaceous pen- dencia sandstones, Potiguar Rift Basin, Brazil显示文摘 | Sylvia M C Luiz F D Rog6rio S | 2000 | AAPG Bul- letin2000，84，11： | 1 |
| 14 | Analysis of pesticides and PCB congeners in serum by GC/MS with SPE sample clean up显示文摘 | Jasna D Siu C Sylvia H YC | 2002 | Toxicology Letters2002，134，： | 1 |
| 15 | Catalytic biofunctional membranes containing site-specifically immobilized enzyme arrays: a review显示文摘 | Butterfield D Allan Dibakar Bhattacharyya Sylvia Daunert | 2001 | Journal of Membrane Science2001，，18： | 1 |
| 16 | Managing the Stiff Elbow: Operative, Nonoperative, and Postoperative Techniques显示文摘 | Sylvia A. Dávila | 2006 | Journal of Hand Therapy2006，，2： | 1 |
| 17 | lα, 25-dihydroxyvitamin D3 and 24R, 25- dihydroxyvitamin D3 modulate growth plate ehondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogenactivated protein kinase 显示文摘 | Schwartz Z Ehland H Sylvia VL Larsson D Hardin RR Bingham V | 2002 | Endocrinology2002，143，7： | 1 |
| 18 | Isolation and characterization of a secretory component of Echinococcus multilocularis metacestodes potentially involved in modulating the host-parasite interface显示文摘 | Mirjam W Adriana B Sylvia D | 2004 | Infect Immun2004，72，1： | 1 |
| 19 | Id genes and proteins as promising targets in cancer therapy 显示文摘 | Sylvia F Robert JD Pierre-Yves D | 2004 | Trends Mol Med2004，10，8： | 1 |
| 20 | 24,25-(OH)2D3 regulates cartilage and bone via autocrine and endocrine mech nisms显示文摘 | Boyan B D Sylvia V L Dean D D | 2001 | Steroids2001，66，： | 1 |
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