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| 1 | Tacrolimus confers lower acute rejection rates and better renal allograft survival compared to cyclosporine显示文摘AIM To compare the impact of tacrolimus(FK) and cyclosporine(CYA) on acute rejection and graft survival and to assess the predominant causes of graft loss between patients receiving these two calcineurin inhibitors(CNIs).METHODS Retrospective review of 1835 patients who received a kidney transplant(KTX) between 1999-2012. Patients were grouped based on initial CNI utilized: 1195 in FK group, 640 in CYA group. Data on baseline characteristics, clinical outcomes, and causes of graft loss in both groups were analyzed. RESULTS Cumulative acute rejection rates were 14% in the FK vs 24% in the CYA group. Despite more marginal donor characteristics in the FK group, these patients had better graft survival rates compared to the CYA group. Three and five year graft survival rates were 88% and 84% respectively in the FK group compared to 79% and 70% respectively in the CYA group(P < 0.001). After multivariate analysis, which controlled for confounders, FK use was a strong predictor for lower acute rejectionrates [odds ratio(OR) 0.60, 95%CI: 0.45-0.79] and better renal allograft survival(OR 0.740, 95%CI: 0.58-0.94). Death with a functioning graft was the most common cause of graft loss in both groups. Common causes of death included cardiovascular disease, infections, and malignancies. Chronic allograft nephropathy was also found to be an important cause of graft loss, being more prevalent in the CYA group. CONCLUSION The use of FK-based maintenance immunosuppression therapy is associated with a significantly lower rate of acute rejection and better graft survival compared to CYA-based regimen. Individualizing immunosuppression through risk-stratified CNI choice may lead to improved outcomes across all spectra of KTX patients. | Mahmoud Kamel Manish Kadian Titte Srinivas David Taber Maria Aurora Posadas Salas | 2016 | World Journal of Transplantation2016，6，4： | 2 |
| 2 | Waling for prevention of cardiovascular disease in men and women:a systematic review of observational studies显示文摘 | Boone-Heinonen J Evenson KR Taber DR | 2009 | Obes Rev2009，10，2： | 1 |
| 3 | Forceps design for transferring honey bee eggs显示文摘 | STEPHEN TABER | 1960 | Journal of Econokmic Entomology1960，54，2： | 1 |
| 4 | EOR screening criteria revisited-Part 1: Introduction,to screening criteria and enhanced recovery field projects-SPE显示文摘 | Taber Seright R S | 2001 | Reservoir Engineering2001，12，3： | 1 |
| 5 | Preferences for blood-based colon cancer screening differ by race/ ethnicity显示文摘 | Taber JM Aspinwall LG Heichman KA | 2014 | Am J Health Behav2014，38，3： | 1 |
| 6 | Phase Ⅱ trial of PS-341 in patients with renal cell cancer:a University of Chicago phase Ⅱ consortiumstudy显示文摘 | Davis NB Taber DA Ansari RH | 2004 | J Clin Oncol2004，22，： | 1 |
| 7 | 10-hydroxy-delta 2-decdnoic acid, an antibiotic found in royal jelly显示文摘 | BLUM M S NOVAK A F TABER S | 1959 | Science1959，130，3373： | 1 |
| 8 | UK Quality In-dicator Project (UK QIP) and the UK independent healthcare sector:a new development显示文摘 | R ichard Thom son Sally Taber Joanne Lally | | 0，，01： | 1 |
| 9 | Early Aspirin Therapy May Reduce Hepatic Artery Thrombosis in Liver Transplantation显示文摘 | R. Shay D. Taber N. Pilch H. Meadows S. Tischer J. McGillicuddy C. Bratton P. Baliga K. Chavin | 2012 | Transplantation Proceedings2012，，： | 1 |
| 10 | Maturity of fresh market sweet corn with direct-seeded plants,transplants,clear plastic mulch,and rowcover combinations显示文摘 | Aguyoh J Taber H G Lawson V | 1999 | HortTechnology1999，9，3： | 1 |
| 11 | Cardiac calcification in adult hemodialysis patients, a link between end-stage renal disease and cardiovascular disease? 显示文摘 | Raggi P Boulay A Chasan Taber S | 2002 | J Am Coll Cardiol2002，39，4： | 1 |
| 12 | Job Satisfaction and Their Correlates 显示文摘 | Seashore SE Taber TD | 1975 | American Behavior& Scientists1975，18，3： | 1 |
| 13 | Mechanical stress as a regulator of cytoskeletal contractility and nuclear shape in embryonic epithelia显示文摘 | Filas BA Bayly PV Taber LA | 2011 | Ann Biomed Eng2011，39，1： | 1 |
| 14 | Acute myocardial infarction caused by a myocardial bridge treated with intracoronary stenting显示文摘 | Smith SC Taber MT Robiolio PA | 1997 | Cathet Cardiovasc Diagn1997，42，2： | 1 |
| 15 | Carbon dioxide flooding显示文摘 | Martin F D Taber J J | 1992 | J Petrol Technol1992，44，4： | 1 |
| 16 | Relationship of Stress to Individually and Organizationally Valued Strategies: Nigher Order Needs as a Moderator显示文摘 | Beehr T A Walsh J T Taber T D | 1976 | Journal of Applied Psychology1976，61，1： | 1 |
| 17 | EOR screening criteria revisited-Part 1: introduction,to screening criteria and enhanced recovery field projectsSPE显示文摘 | TABER J J SERIGHT R S | 2001 | Reservoir Engineering2001，12，3： | 1 |
| 18 | Mechanics of ventricular torsion显示文摘 | Taber LA Yang M Podazus WW | 1996 | J Biomech1996，29，6： | 1 |
| 19 | Mechaincs of ventricular Torsion显示文摘 | Taber LA Yang M Podszus WW | 1996 | J Biomech1996，29，： | 1 |
| 20 | Horizontal injection and prodution wells for EOR or waterflooding显示文摘 | Taber J J Ssright R S | 1992 | SPE1992，，： | 1 |
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