|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does a combined intervention program of repetitive transcranial magnetic stimulation and intensive occupational therapy affect cognitive function in patients with post-stroke upper limb hemiparesis?显示文摘Low-frequency repetitive transcranial magnetic stimulation(LF-r TMS) to the contralesional hemisphere and intensive occupational therapy(i OT) have been shown to contribute to a significant improvement in upper limb hemiparesis in patients with chronic stroke. However, the effect of the combined intervention program of LF-r TMS and i OT on cognitive function is unknown. We retrospectively investigated whether the combined treatment influence patient's Trail-Making Test part B(TMT-B) performance, which is a group of easy and inexpensive neuropsychological tests that evaluate several cognitive functions. Twenty-five patients received 11 sessions of LF-r TMS to the contralesional hemisphere and 2 sessions of i OT per day over 15 successive days. Patients with right- and left-sided hemiparesis demonstrated significant improvements in upper limb motor function following the combined intervention program. Only patients with right-sided hemiparesis exhibited improved TMT-B performance following the combined intervention program, and there was a significant negative correlation between Fugl-Meyer Assessment scale total score change and TMT-B performance. The results indicate the possibility that LF-r TMS to the contralesional hemisphere combined with i OT improves the upper limb motor function and cognitive function of patients with right-sided hemiparesis. However, further studies are necessary to elucidate the mechanism of improved cognitive function. | Takatoshi Hara Masahiro Abo Kiyohito Kakita Takeshi Masuda Ryunosuke Yamazaki | 2016 | Neural Regeneration Research2016，11，12： | 18 |
| 2 | Infrequent p53 gene mutation and expression of the cardia adenocarcinomas from a high-incidence area of Southwest China显示文摘INTRODUCTIONAdenocarcinomas of the cardia are the lesionsarising from the proximal stomach or within 3 cm ofthe gastroesophageal junction.These cancerstended to be advanced at the time of presentation,usually with poor prognosis.In recent decade,the incidence of adenocarcinoma of gastric eardiaand esophagus are increasing steadily,while therehas been a decrease in the proportion of the cancersarising from the distal stomach.The | Naoko lida Hideaki Oda Shigetoshi Aiso Takatoshi Ishikawa | 2000 | World Journal of Gastroenterology2000，6，5： | 17 |
| 3 | Metabolism and Long-distance Translocationof Cytokinins显示文摘During plant development, distantly-located organs must communicate in order to adapt morphological and physiological features in response to environmental inputs. Among the recognized signaling molecules, a class of phytohormones known as the cytokinins functions as both local and long-distance regulatory signals for the coordination of plant development. This cytokinin-dependent communication system consists of orchestrated regulation of the metabolism, translocation, and signal transduction of this phytohormone class. Here, to gain insight into this elaborate signaling system, we summarize current models of biosynthesis, transmembrane transport, and long-distance translocation of cytokinins in higher plants. | Toru Kudo Takatoshi Kiba Hitoshi Sakakibara | 2010 | Journal of Integrative Plant Biology2010，52，1： | 16 |
| 4 | Coronary artery disease in type 2 diabetes mellitus:Recent treatment strategies and future perspectives显示文摘Patients with type 2 diabetes mellitus(T2DM) are at a higher risk of developing coronary artery disease(CAD) than are non-T2 DM patients. Moreover, the clinical outcomes in CAD with T2 DM are poor despite improvements in medications and other interventions. Coronary artery bypass grafting is superior to percutaneous coronary intervention in treating multivessel coronary artery disease in diabetic patients. However, selecting a revascularization strategy depends not only on the lesion complexity but also on the patient's medical history and comorbidities. Additionally, comprehensive risk management with medical and non-pharmacological therapies is important, as is confirmation regarding whether the risk-management strategies are being appropriately achieved. Furthermore, non-pharmacological interventions using exercise and diet during the earlier stages of glucose metabolism abnormalities, such as impaired glucose tolerance, might be beneficial in preventing the development or progression of T2 DM and in reducing the occurrence of cardiovascular events. | Ryo Naito Takatoshi Kasai | 2015 | World Journal of Cardiology2015，7，3： | 12 |
| 5 | Optimal treatment strategies for hepatic portal venous gas:A retrospective assessment显示文摘BACKGROUND Hepatic portal venous gas(HPVG)generally indicates poor prognoses in patients with serious intestinal damage.Although surgical removal of the damaged portion is effective,some patients can recover with conservative treatments.AIM To establish an optimal treatment strategy for HPVG,we attempted to generate computed tomography(CT)-based criteria for determining surgical indication,and explored reliable prognostic factors in non-surgical cases.METHODS Thirty-four cases of HPVG(patients aged 34-99 years)were included.Necessity for surgery had been determined mainly by CT findings(i.e.free-air,embolism,lack of contrast enhancement of the intestinal wall,and intestinal pneumatosis).The clinical data,including treatment outcomes,were analyzed separately for the surgical cases and non-surgical cases.RESULTS Laparotomy was performed in eight cases(surgical cases).Seven patients(87.5%)survived but one(12.5%)died.In each case,severe intestinal damage was confirmed during surgery,and the necrotic portion,if present,was removed.Non-occlusive mesenteric ischemia was the most common cause(n=4).Twentysix cases were treated conservatively(non-surgical cases).Surgical treatments had been required for twelve but were abandoned because of the patients’poor general conditions.Surprisingly,however,three(25%)of the twelve inoperable patients survived.The remaining 14 of the 26 cases were diagnosed originally as being sufficiently cured by conservative treatments,and only one patient(7%)died.Comparative analyses of the fatal(n=10)and recovery(n=16)cases revealed that ascites,peritoneal irritation signs,and shock were significantly more frequent in the fatal cases.The mortality was 90%if two or all of these three clinical findings were detected.CONCLUSION HPVG related to intestinal necrosis requires surgery,and our CT-based criteria are probably useful to determine the surgical indication.In non-surgical cases,ascites,peritoneal irritation signs and shock were closely associated with poor prognoses,and are applicable as predictors of patients’prognoses. | Masanori Gonda Tatsuya Osuga Yoshihiro Ikura Kazunori Hasegawa Kentaro Kawasaki Takatoshi Nakashima | 2020 | World Journal of Gastroenterology2020，26，14： | 8 |
| 6 | HFW管线钢管焊缝的高可靠性技术显示文摘为了解决HFW管线钢管焊缝可靠性问题,通过使用高速摄像机实现了HFW焊接过程的动态可视化,并构建了一个HFW数值分析模型,从而优化HFW焊接条件并实现焊缝区域的均匀加热。试验结果表明,焊接条件优化后开发出的HFW钢管焊缝金属的夏比韧脆转变温度达到-90℃,且具有较高的低温吸收能量值。此外,开发的点融合串列束超声波检验方法实现了焊缝区氧化物的实时连续检测,其灵敏度为常规方法的10倍以上。 | 孙宏 王志太 刘振伟 OKABE Takatoshi IIZUKA Yukinori IGI Satoshi | 2015 | 焊管2015，38，12： | 3 |
| 7 | An Introduction to the Chinese Speech Recognition Front-End of the NICT/ATR Multi-Lingual Speech Translation System显示文摘This paper introduces several important features of the Chinese large vocabulary continuous speech recognition system in the NICT/ATR multi-lingual speech-to-speech translation system. The features include: (1) a flexible way to derive an information rich phoneme set based on mutual information between a text corpus and its phoneme set; (2) a hidden Markov network acoustic model and a successive state split-ting algorithm to generate its model topology based on a minimum description length criterion; and (3) ad-vanced language modeling using multi-class composite N-grams. These features allow a recognition per-formance of 90% character accuracy in tourism related dialogue with a real time response speed. | 张劲松 Takatoshi Jitsuhiro Hirofumi Yamamoto 胡新辉 Satoshi Nakamura | 2008 | Tsinghua Science and Technology2008，13，4： | 3 |
| 8 | Loss-of-Function of a Ubiquitin-Related Modifier Promotes the Mobilization of the Active MITE mPing显示文摘缩小的转换重复的 transposable 元素(螨) 在原核生物、真核细胞的染色体是普遍的,在他们的拷贝数字能达到几的地方千。然而,很少对影响他们的调换的基因因素被知道。这里,我们证明没有任何外长的压力,显著地编码象 ubiquitin 一样蛋白质的基因的那混乱在未经触动的米饭植物提高螨 mPing 的调换活动。我们发现 mPing 的调换活动在在 Rurm1 怀有非功能的等位基因的线更高是远的(瑞斯 ubiquitin 相关的 modifier-1 ) 地点比在野类型的线。尽管 cytosine methylation 模式的改变在外长的压力条件,在整个染色体的 methylation 度, mPing 身体区域,和胁腹 mPing 下面触发 transposable 元素的激活,非功能的 Rurm1 线的区域是未改变的。这研究为在房间以内的基因事故提高的染色体吃惊理论的模型之一提供试验性的证据 transposable 元素的调换活动。 | Takuji Tsukiyama Shota Teramoto KanakoYasuda Akira Horibata Nanako Mori Yutaka Okumoto Masayoshi Teraishi Hiroki Saito Akiko Onishi Kanako Tamura Takatoshi Tanisaka | 2013 | Molecular Plant2013，6，3： | 3 |
| 9 | 人民币钉住美元面临重大选择显示文摘 | Maurice Obstfeld Takatoshi ITO 易纲 何帆 | 2006 | 国际经济评论2006，，4： | 3 |
| 10 | Spontaneous rupture of splenic hamartoma in a patient with hepatitis C virus-related cirrhosis and portal hypertension:A case report and review of the literature显示文摘自发的破裂是脾的错构瘤的稀罕复杂并发症。文学的评论揭示了仅仅四个如此的盒子。就我们的知识而言,这是与肝肝硬化和门静脉高血压联系的脾的错构瘤的自发的破裂的第一份报告。一个 53 岁的女人,被跟随在上面因为大动脉的解剖和丙肝病毒(HCV ) 联系了肝肝硬化,与突然的左胸和肩膀疼痛被提交。腹的超声证明流血的 intraabdominal,和显示的计算断层摄影术脾肿大破裂。突现的脾切除术被执行。手术后的功课是平静的,并且病人在第 13 手术后的天被解除。病理揭示了肿瘤是一个破裂的脾的错构瘤。非肿胀的脾的实质揭示了充血变化。我们认为肝肝硬化和门静脉高血压的存在是为脾的错构瘤的自发的破裂的风险因素。 | Yasuji Seyama Nobutaka Tanaka Yoshio Suzuki Motoki Nagai Takatoshi Furuya Yukihiro Nomura Jimpei Ishii Masakazu Nobori | 2006 | World Journal of Gastroenterology2006，12，13： | 3 |
| 11 | Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy显示文摘 | Hiromitsu Hayashi Toru Beppu Hirohisa Okabe Hideyuki Kuroki Shigeki Nakagawa Katsunori Imai Hidetoshi Nitta Akira Chikamoto Takatoshi Ishiko Hideo Baba | 2014 | Surgery2014，，： | 2 |
| 12 | Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2显示文摘 | Yong Zhao Joshua F. Ransom Ankang Li Vasanth Vedantham Morgan von Drehle Alecia N. Muth Takatoshi Tsuchihashi Michael T. McManus Robert J. Schwartz Deepak Srivastava | 2007 | Cell2007，，2： | 2 |
| 13 | Effect of Sevelamer and Calcium-Based Phosphate Binders on Coronary Artery Calcification and Accumulation of Circulating Advanced Glycation End Products in Hemodialysis Patients显示文摘 | Takatoshi Kakuta Reika Tanaka Toru Hyodo Hajime Suzuki Genta Kanai Mikako Nagaoka Hiroo Takahashi Nobuhito Hirawa Yoichi Oogushi Toshio Miyata Hiroyuki Kobayashi Masafumi Fukagawa Akira Saito | 2011 | American Journal of Kidney Diseases2011，，3： | 2 |
| 14 | Efficacy of peroxisome proliferative activated receptor (PPAR)-α ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models显示文摘 | Takatoshi Kasai Katsumi Miyauchi Takayuki Yokoyama Kouichiro Aihara Hiroyuki Daida | 2005 | Atherosclerosis2005，，2： | 1 |
| 15 | Cardio - ankle vascular index is superior to brachial - ankle pulse wave velocity as an in- dex of arterial tiffness 显示文摘 | Akira T Hiroshi O Takatoshi W | 2013 | Hypertens Res2013，31，7： | 1 |
| 16 | Flow injection analysis of amitrole by chemiluminescent immunosensor using alkaline phosphatase and adamantyl methoxyphosphoryloxy phenyldioxetane显示文摘 | Takatoshi S Masanori Y Hiroya I Kiyoshi M | 2001 | Anal Sci2001，17，5： | 1 |
| 17 | Asymmetric Equilibria in Spatial Compeyition显示文摘 | Takatoshi Tabuchi Jacques-Erancois Thiss | 1995 | International Journal of Industrial Organization1995，，13： | 1 |
| 18 | Capital augmenting technology,and labor market equilibrium显示文摘 | TAKATOSHI T | | 0，，02： | 1 |
| 19 | Treatment of central sleep apnea in patients with heart failure: Now and future显示文摘Heart failure (HF) is known to be associated with sleep-disordered breathing(SDB). In addition to disturbing patients’ sleep, SDB is also associated with a deterioration in the cardiac function and an increased mortality and morbidity.Central sleep apnea (CSA), typically characterized by Cheyne-Stokes breathing(CSB), is increasingly found in patients with HF compared to the general population. An important pathogenetic factor of CSA seen in HF patients is an instability in the control of the respiratory system, characterized by both hypocapnia and increased chemosensitivity. Sympathetic overactivation,pulmonary congestion and increased chemosensitivity associated with HF stimulate the pulmonary vagal irritant receptor, resulting in chronic hyperventilation and hypocapnia. Additionally, the repetitive apnea and arousal cycles induce cyclic sympathetic activation, which may worsen the cardiac prognosis. Correcting CSB may improve both patient’s quality of life and HF syndrome itself. However, a treatment for HF in patients also experiencing CSA is yet to be found. In fact, conflicting results from numerous clinical studies investigating sleep apnea with HF guide to a troubling question, that is whether(or not) sleep apnea should be treated in patients with HF? This editorial attempts to both collect the current evidence about randomized control trials investigating CSA in patients with HF and highlight the effect of specific CSA treatments on cardiovascular endpoints. | Azusa Murata Takatoshi Kasai | 2019 | World Journal of Respirology2019，9，1： | 1 |
| 20 | Electronic structure, bonding nature, and charge transfer in Ba@ Si20 and Si20 clusters: An ab initio study显示文摘 | Takatoshi Nagano Kazuo Tsumuraya Singh D J | 2001 | Phys Rev B2001，64，15： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员