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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Coal fires burning out of control around the world: thermodynamic recipe for environmental catastrophe显示文摘 | Glenn B Stracher Tammy P Taylor | 2004 | International Journal of Coal Geology2004，，1： | 2 |
| 3 | Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex显示文摘 | Le Blanc K Tammi L Sundberg B | 2003 | Scand J Immonol2003，57，1： | 1 |
| 4 | Cloning of a human parvovirus by molecular screening of respiratory tract samples显示文摘 | Allander T Tammi MT Eriksson M Bjerkner A Tiveljung-Lin- dell A Andersson B | 2005 | Proc Natl Acad Sci U S A2005，102，12： | 1 |
| 5 | Hyaluronan-cell interactions in cancer and vascular disease 显示文摘 | TOOLE B WIGHT T TAMMI M | 2002 | Biol Chem2002，277，7： | 1 |
| 6 | Use of WL medium to profile native flora fermentations显示文摘 | CHRISTINA L P JAMES A B TAMMI L O | 2001 | American Journal of Enology and Viticulture2001，52，3： | 1 |
| 7 | Hyaluronan-cell in- teractions in cancer and vau|ar disea 显示文摘 | TOOLE B P WIGHT T N TAMMI M I | 2002 | J Biol Chem2002，277，7： | 1 |
| 8 | C3 plants en- hance rates of photosynthesis by reassimilating photorespired and respired COe 显示文摘 | Florian A B Tammy L S Rowan F S | 2013 | Plant Cell and Environment2013，36，： | 1 |
| 9 | Ac-cumlationof Cholesteralwith Agein Human Bruch's Mem-brance显示文摘 | Christine A Curcio C L Tammy B | 2001 | Invest Opthalmol Vis Sci2001，42，： | 1 |
| 10 | Use of WL medium to profile native flora fermentations显示文摘 | CHRISTINA L P JAMES A B TAMMI L O | 2001 | American Journal of Enology and Viticulture2001，52，3： | 1 |
| 11 | Cloning of a human parvovirus by molecular screening of respiratory tract samples显示文摘 | Allander T Tammi M T Eriksson M Bjerkner A Tiveljung-Lindell A Andersson B | 2005 | Proc Natl Acad Sci U S A2005，102，12： | 1 |
| 12 | Use of WL Medium to Profile Natire Flora Fermentations 显示文摘 | Christina L P James A B Tammi L O | 2001 | American Journal of Enology and Viticulture2001，52，3： | 1 |
| 13 | Use of WL mediumto profile native flora fermentations显示文摘 | CHRISTINA L P JAMES A B TAMMI L O | 2001 | American Journal of Enology andViticulture2001，52，3： | 1 |
| 14 | High dose andlow dose Lactobacillus acidophilus exerted differenti-al immunemodulating effects on T cell immune re-sponses induced by an oral humanrotavirus vaccine ingnotobiotic pigs显示文摘 | WEN K LI G H TAMMY B | 2012 | Vaccine2012，30，： | 1 |
| 15 | Cloning of a human parvovirus by molecular screening of respiratory tract samples显示文摘 | Allander T Tammi MT Eriksson M Bjerkner A Tiveljung-Lin-dell A Andersson B | | 0，，： | 1 |
| 16 | Hyaluronan-cell interac-tions in cancer and vascular disease显示文摘 | Toole B P Wight T N Tammi M I | 2002 | J Biol Chem2002，277，7： | 1 |
| 17 | Conversion of epoxides to thi- iranes with thiourea or ammonium thiocyanate catalyzed with poly (4-Vinyl Pyridine )-Ce ( OTf)4 显示文摘 | Iranpoor N Tammi B Shekarriz M | 1999 | Synthetic Communications1999，29，19： | 1 |
| 18 | Use of wL medium to profile native flora fermentations显示文摘 | Christina L P James A B Tammi L O | 2001 | AM J Enol Vitic2001，52，3： | 1 |
| 19 | The mechanism of action of sugar acetals as nucleating agents for polypropylene显示文摘 | TAMMY L S DIVAKARAN M LONG K B | 1994 | Macromolecules1994，27，18： | 1 |
| 20 | Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex显示文摘 | Le Blanc K Tammi L Sundberg B | 2003 | Scand J Immunol2003，57，1： | 1 |
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