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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 3 | Abdominal surgery in nonagenarians:short-term results显示文摘 | Arenal JJ de Teresa G Tinoco C | 2007 | Surg Today2007，37，12： | 1 |
| 4 | Transparent conducting Nnc oxide thin films doped with aluminum and molybdenum显示文摘 | JOEL N D TIMOTHY A G DAVID M W TERESA M B MATTHEW Y BOBBY T TIMOTHY J C | 2007 | Journal V-acuum Society Technology2007，25，4： | 1 |
| 5 | Pollen biology in four Mediterranean Quercus species显示文摘 | Teresa Gómez-Casero M T Hidalgo P J García-Mozo H Dominguez E Galán C | | 0，，： | 1 |
| 6 | Pediatric temperature measurement and child/parent/nurse preference using three temperature measurement instruments显示文摘 | Sharon J Rebecca G Teresa C | 2003 | Journal of Pediatric Nursing2003，18，5： | 1 |
| 7 | Hepatocyte growth factor and its receptor Met are induced in crescentic glomerulonephritis显示文摘 | Teresa R Marilena G Giovanni C | 2005 | Nephrol Dial Transplant2005，20，： | 1 |
| 8 | Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities显示文摘 | Mar L Antonio G S Maria Teresa G C | 2006 | J Agric Food Chem2006，54，： | 1 |
| 9 | Antioxi-Dant Properties of Catechies and Proanthocyanidins: Effect of poly-M erization, Galloylation and G lycosylation显示文摘 | PLUMP G W DE PASCUAL TERESA S SANTOS BUELGA C | 1998 | Free Radic Res1998，29，4： | 1 |
| 10 | Hepatocyte growth factor and its receptor met are induced in crescentic glomerulonephritis 显示文摘 | TERESA R MARILENA G GIOVANNI C | 2005 | Nephrol Dial Transplant2005，20，： | 1 |
| 11 | The effect of micronutrient deficiencies on child growth: a review of results from community-based supplementation trials 显示文摘 | RIVERA J A CHRISTINE H TERESA G C | 2003 | J Nutr2003，133，11： | 1 |
| 12 | Evaluation of the antioxidant properties of fruits显示文摘 | ALONSO M G TERESA S P BUELGA C S | 2004 | FC2004，84，： | 1 |
| 13 | You can' t manage right what you can' t measure well: technological innovation efficlency显示文摘 | Claudio C C Cristina B S Teresa G M | 2013 | Research Policy2013，，42： | 1 |
| 14 | Dexamethasone prevents Granulocyte/macrophage colony stimulating factor-induced nuclear factor-κB activation,inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line显示文摘 | Ana L V Margarida G M Teresa C | 2003 | Med Inflamm2003，12，2： | 1 |
| 15 | Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization显示文摘 | Ignacio M Ricardo C Teresa G | 2003 | J Pharmacol Exp Ther2003，304，： | 1 |
| 16 | Influence of SO2 on the consumption of nitrogen compounds through alcoholic fermentation of must sterilized by pulsed electric fields显示文摘 | TERESA G C ROBERT M F MARGALUZ A G | 2007 | Food Chemistry2007，103，3： | 1 |
| 17 | Cartilaginous Behavior in Nasal Surgery: A Comparative Observational Study显示文摘 | Lázaro Cárdenas-Camarena Rodolfo Bayardo Gómez María Teresa Guerrero Milton Solis José Guerrerosantos | 1998 | Annals of Plastic Surgery1998，，1： | 1 |
| 18 | Continuous quality improvement in primary health care:A five year project显示文摘 | Teresa M G Antonio C L Antonio T L | 1999 | European Journal of Public Health1999，9，2： | 1 |
| 19 | Pediatric temperature measurement and child/parent/nurse preference using three temperature measurement instruments显示文摘 | Sharon J Rebecca G Teresa C | 2003 | Journal of pediatric Nursing2003，18，5： | 1 |
| 20 | Myosin light chain is a novel shrimp allergen, Lit v 3 显示文摘 | Rosalia A Galina G Ludmilla B Teresa C Carlos B Maria D I Sampson H A Kirsten B | 2008 | Journal of Allergy and Clinical Immunology2008，122，4： | 1 |
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