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| 1 | Lateral buckling of non-trenched high temperature pipelines with pipelay imperfections显示文摘An analysis method for the buckling process of a pipe section with a random pipelay imperfection is proposed. Four basic lateral modes,acquired by fi nite-element(FE) eigenvalue buckling analysis,are combined to provide the needed grid conf igurations for describing a real pipelay imperfection and an arc-length algorithm is used to analyze the snap-through process of the shell-element-grid model under nonlinear frictional boundary conditions. This paper also presents evaluation methods for the lateral buckling of two types of pipe-in-pipe systems that are used in the offshore oil and gas industry. For evaluating the buckling and postbuckling of compliant pipe-in-pipe systems FE analyses were carried out to judge the occurrence of the system buckling and furthermore to check postbuckling stresses induced in the buckles. The calculated results of the modifi ed Riks algorithm indicate that only when high temperature would not trigger an abrupt short-wavelength buckle and when no yielding has been induced in the unavoidable long-wavelength buckles,the thermal stability and safety of compliant pipe-in-pipe systems can be proved. In the non-compliant pipe-in-pipe systems,fi rstly small-amplitude buckles of the carrier pipe may occur in the annulus between carrier pipe and casing pipe and the contact forces between the spacers and the casing pipe may drive the buckle of the pipe-in-pipe systems on the seabed. Based on the classical analytical solution of pipe buckling,four potential buckling modes corresponding to fi nite-element models are developed to evaluate the stability and the postbuckling strength of such pipe-in-pipe systems. | Zhao Tianfeng Duan Menglan Pan Xiaodong Feng Xianhong | 2010 | Petroleum Science2010，7，1： | 3 |
| 2 | Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics显示文摘Stanene(Sn)-based materials have been extensively applied in industrial production and daily life,but their potential biomedical application remains largely unexplored,which is due to the absence of the appropriate and effective methods for fabricating Sn-based biomaterials.Herein,we explored a new approach combining cryogenic exfoliation and liquid-phase exfoliation to successfully manufacture two-dimensional(2D)Sn nanosheets(SnNSs).The obtained SnNSs exhibited a typical sheet-like structure with an average size of~100 nm and a thickness of~5.1 nm.After PEGylation,the resulting PEGylated SnNSs(SnNSs@PEG)exhibited good stability,superior biocompatibility,and excellent photothermal performance,which could serve as robust photothermal agents for multi-modal imaging(fluorescence/photoacoustic/photothermal imaging)-guided photothermal elimination of cancer.Furthermore,we also used first-principles density functional theory calculations to investigate the photothermal mechanism of SnNSs,revealing that the free electrons in upper and lower layers of SnNSs contribute to the conversion of the photo to thermal.This work not only introduces a new approach to fabricate 2D SnNSs but also establishes the SnNSs-based nanomedicines for photonic cancer theranostics.This new type of SnNSs with great potential in the field of nanomedicines may spur a wave of developing Sn-based biological materials to benefit biomedical applications. | Jiang Ouyang Ling Zhang Leijiao Li Wei Chen Zhongmin Tang Xiaoyuan Ji Chan Feng Na Tao Na Kong Tianfeng Chen You-Nian Liu Wei Tao | 2021 | Nano-Micro Letters2021，13，6： | 1 |
| 3 | Rockburst mechanism and the law of energy accumulation and release in mining roadway: a case study显示文摘The rockburst dynamic disasters in the process of deep coal mining become more and more serious.Taking the rockburst occurred in the 23130 working face of Yuejin Coal Mine as the engineering background,we study the characteristics of mining stress feld around roadway,the plastic failure morphological characteristics of surrounding rock and the accumulation/release law of elastic energy before and after burst.An analysis model quantitatively describing the physical process of rockburst in the mining roadway is established,and the calculation method of dynamic release of elastic energy in the physical process of rockburst is educed.The mechanism of rockburst in mining roadway is revealed.The results show that an“L-shaped”stress concentration zone is formed within 100 m of the 23130 working face,and the principal stress ratio of the surrounding rock of the transportation roadway is 2.59–4.26.The change of the direction of the maximum principal stress has a signifcant efect on the burst appearance characteristics.The failure strength of diferent sections of the mining roadway is characterized by the elastic energy release value.With the increase of the working face distance,the elastic energy released by burst failure and the expansion variation of failure boundary radius show a nonlinear variation law that tends to decrease steadily after sharp fuctuation.The closer to the working face,the higher the burst risk.At a distance of 10 m from the working surface,the maximum principal stress reaches its maximum value.The butterfy-shaped failure system generated by the surrounding rock of the roadway has energy self-sustainability,and the elastic energy released by the sudden expansion of the butterfy leaf is enough to cause a burst damage of 1.9 magnitude.This work could provide theoretical support for the prediction and prevention of rockburst. | Feng Du Ji Ma Xiaofei Guo Tianfeng Wang Xiaohang Dong Jiashuo Li Shulei He Dilinaer Nuerjuma | 2022 | International Journal of Coal Science & Technology2022，9，5： | 1 |
| 4 | Selenium speciation determines the angiogenesis effect through regulating selenoproteins to trigger ROS-mediated cell apoptosis and cell cycle arrest显示文摘Tumor angiogenesis is closely related to tumor development,immune escape,and drug resistance.Therefore,the development of effective anti-tumor angiogenesis drugs is of great research significance.Although the current clinical angiogenesis inhibitors have achieved certain efficacy,they also pose the problems of limited and short duration of efficacy,drug resistance,and intrinsic toxicity.Anti-tumor angiogenesis strategies targeting endothelial cells(ECs)have attracted widespread attention in the development of highly effective and low toxicity anti-angiogenesis inhibitors.Studies have verified that the trace element selenium(Se)can inhibit tumor growth by inhibiting tumor angiogenesis through different mechanisms.Nevertheless,it is unclear whether Se speciation has different effects on anti-tumor angiogenesis.Herein,we found that Se exhibited effective anti-angiogenic activity,and its mechanisms of activity were determined by its chemical speciation.Organic Se can significantly inhibit tumor angiogenesis by targeting thioredoxin reductase(TrxR)to trigger cell apoptosis and cell cycle arrest and by increasing reactive oxygen species(ROS)production in ECs.Inorganic Se can induce cell cycle arrest and increase ROS production in ECs,showing promising anti-angiogenic effects.Se nanoparticles(SeNPs)slightly inhibit tumor angiogenesis by inducing apoptosis and cell cycle arrest and by increasing the production of ROS.In summary,this study elucidates the anti-angiogenic activity of Se speciation control with a view to providing a scientific reference for the design and development of novel Se-based highly effective and low toxicity angiogenesis inhibitors. | Bin Feng Yan Zhang Ting Liu Leung Chan Tianfeng Chen Jianfu Zhao | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
| 5 | Quantum information transfer between a two-level and a four-level quantum systems显示文摘Quantum mechanics provides a disembodied way to transfer quantum information from one quantum object to another.In theory,this quantum information transfer can occur between quantum objects of any dimension,yet the reported experiments of quantum information transfer to date have mainly focused on the cases where the quantum objects have the same dimension.Here,we theoretically propose and experimentally demonstrate a scheme for quantum information transfer between quantum objects of different dimensions.By using an optical qubit-ququart entangling gate,we observe the transfer of quantum information between two photons with different dimensions,including the flow of quantum information from a four-dimensional photon to a twodimensional photon and vice versa.The fidelities of the quantum information transfer range from 0.700 to 0.917,all above the classical limit of 2/3.Our work sheds light on a new direction for quantum information transfer and demonstrates our ability to implement entangling operations beyond two-level quantum systems. | TIANFENG FENG QIAO XU LINXIANG ZHOU MAOLIN LUO WUHONG ZHANG XIAOQI ZHOU | 2022 | Photonics Research2022，10，12： | 0 |
| 6 | Steering paradox for Einstein–Podolsky–Rosen argument and its extended inequality显示文摘The Einstein–Podolsky–Rosen(EPR)paradox is one of the milestones in quantum foundations,arising from the lack of a local realistic description of quantum mechanics.The EPR paradox has stimulated an important concept of“quantum nonlocality,”which manifests itself in three types:quantum entanglement,quantum steering,and Bell’s nonlocality.Although Bell’s nonlocality is more often used to show“quantum nonlocality,”the original EPR paradox is essentially a steering paradox.In this work,we formulate the original EPR steering paradox into a contradiction equality,thus making it amenable to experimental verification.We perform an experimental test of the steering paradox in a two-qubit scenario.Furthermore,by starting from the steering paradox,we generate a generalized linear steering inequality and transform this inequality into a mathematically equivalent form,which is friendlier for experimental implementation,i.e.,one may measure the observables only in the x,y,or z axis of the Bloch sphere,rather than other arbitrary directions.We also perform experiments to demonstrate this scheme.Within the experimental errors,the experimental results coincide with theoretical predictions.Our results deepen the understanding of quantum foundations and provide an efficient way to detect the steerability of quantum states. | TIANFENG FENG CHANGLIANG REN QIN FENG MAOLIN LUO XIAOGANG QIANG JING-LING CHEN XIAOQI ZHOU | 2021 | Photonics Research2021，9，6： | 0 |
| 7 | RNA2Immune:A Database of Experimentally Supported Data Linking Non-coding RNA Regulation to The Immune System显示文摘Non-coding RNAs(ncRNAs),such as microRNAs(miRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(circRNAs),have emerged as important regulators of the immune system and are involved in the control of immune cell biology,disease pathogenesis,as well as vaccine responses.A repository of ncRNA-immune associations will facilitate our understanding of ncRNA-dependent mechanisms in the immune system and advance the development of therapeutics and prevention for immune disorders.Here,we describe a comprehensive database,RNA2Immune,which aims to provide a high-quality resource of experimentally supported database linking ncRNA regulatory mechanisms to immune cell function,immune disease,cancer immunology,and vaccines.The current version of RNA2Immune documents 50,433 immune-ncRNA associations in 42 host species,including(1)6690 ncRNA associations with immune functions involving 31 immune cell types;(2)38,672 ncRNA associations with 348 immune diseases;(3)4833 ncRNA associations with cancer immunology;and(4)238 ncRNA associations with vaccine responses involving 26 vaccine types targeting 22 diseases.RNA2Immune provides a user-friendly interface for browsing,searching,and downloading ncRNA-immune system associations.Collectively,RNA2Immune provides important information about how ncRNAs influence immune cell function,how dysregulation of these ncRNAs leads to pathological consequences(immune diseases and cancers),and how ncRNAs affect immune responses to vaccines. | Jianjian Wang Shuang Li Tianfeng Wang Si Xu Xu Wang Xiaotong Kong Xiaoyu Lu Huixue Zhang Lifang Li Meng Feng Shangwei Ning Lihua Wang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，2： | 0 |
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