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| 1 | New advances in in-situ thermal desorption technology for contaminated soil显示文摘With the development of ecological civilization and economic construction,remediation of contaminated soils has caused more and more concern of scientists and engineers.Situ thermal desorption is a mature and effective technology which is especially suitable for the contaminated soil of relocated chemical plant[1,2],Compared with in-situ chemical oxidation and ectopic thermal desorption,the in-situ thermal desorption has stronger applicability and higher repair efficiency.The main applications of the in-situ thermal desorption technology are semi-volatile and volatile organic pollutants. | SHI Yan LUO ZiHao WANG YiXuan CAI MaoLin YANG LiMan | 2019 | Science China(Technological Sciences)2019，62，11： | 7 |
| 2 | Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication显示文摘HepatitisBvirus(HBV)infection causes acuteand chronic liver diseases,but is not directly cytopathic.Liver injury results fromrepeated attempts of the cellular immune response system to control the viral infection.Here,we investigate the roles of cellular factors and signaling pathways involved in the regulation of HBV replication to reveal the mechanism underlying HBV infection and pathogenesis.Weshowthat collagen triple helix repeat containing 1(CTHRC1)expression is elevated in HBV-infected patients andin HBV-transfected cells through epigenetic modification and transcriptional regulation.CTHRC1 facilitates HBV replication in cultured cells and BALB/c mice by activating the PKCa/ERK/JNK/c-Jun cascade to repress the IFN/JAK/STAT pathway.HBV-activated CTHRC1 downregulates the activityof typeI interferon(IFN),theproductionof IFN-stimulatedgenes(ISGs),andthephosphorylationofsignal transducerandactivator of transcription 1/2(STAT1/2),whereas it upregulates the phosphorylation and ubiquitination of type I IFN receptors(IFNARa/b).Thus,our results showthat HBV uses a novelmechanismto hijack cellular factors and signal cascades in order to evade host antiviral immunity and maintain persistent infection.We also demonstrate that CTHRC1 has a novel role in viral infection. | Lan Bai Wei Zhang Li Tan Hongchuan Yang Maolin Ge Chengliang Zhu Rui Zhang Yanhua Cao Junbo Chen Zhen Luo Wenzhe Ho Fang Liu Kailang Wu Jianguo Wu | 2015 | Journal of Molecular Cell Biology2015，7，6： | 2 |
| 3 | Quantum information transfer between a two-level and a four-level quantum systems显示文摘Quantum mechanics provides a disembodied way to transfer quantum information from one quantum object to another.In theory,this quantum information transfer can occur between quantum objects of any dimension,yet the reported experiments of quantum information transfer to date have mainly focused on the cases where the quantum objects have the same dimension.Here,we theoretically propose and experimentally demonstrate a scheme for quantum information transfer between quantum objects of different dimensions.By using an optical qubit-ququart entangling gate,we observe the transfer of quantum information between two photons with different dimensions,including the flow of quantum information from a four-dimensional photon to a twodimensional photon and vice versa.The fidelities of the quantum information transfer range from 0.700 to 0.917,all above the classical limit of 2/3.Our work sheds light on a new direction for quantum information transfer and demonstrates our ability to implement entangling operations beyond two-level quantum systems. | TIANFENG FENG QIAO XU LINXIANG ZHOU MAOLIN LUO WUHONG ZHANG XIAOQI ZHOU | 2022 | Photonics Research2022，10，12： | 0 |
| 4 | Detection Algorithm of Laboratory Personnel Irregularities Based on Improved YOLOv7显示文摘Due to the complex environment of the university laboratory,personnel flow intensive,personnel irregular behavior is easy to cause security risks.Monitoring using mainstream detection algorithms suffers from low detection accuracy and slow speed.Therefore,the current management of personnel behavior mainly relies on institutional constraints,education and training,on-site supervision,etc.,which is time-consuming and ineffective.Given the above situation,this paper proposes an improved You Only Look Once version 7(YOLOv7)to achieve the purpose of quickly detecting irregular behaviors of laboratory personnel while ensuring high detection accuracy.First,to better capture the shape features of the target,deformable convolutional networks(DCN)is used in the backbone part of the model to replace the traditional convolution to improve the detection accuracy and speed.Second,to enhance the extraction of important features and suppress useless features,this paper proposes a new convolutional block attention module_efficient channel attention(CBAM_E)for embedding the neck network to improve the model’s ability to extract features from complex scenes.Finally,to reduce the influence of angle factor and bounding box regression accuracy,this paper proposes a newα-SCYLLA intersection over union(α-SIoU)instead of the complete intersection over union(CIoU),which improves the regression accuracy while increasing the convergence speed.Comparison experiments on public and homemade datasets show that the improved algorithm outperforms the original algorithm in all evaluation indexes,with an increase of 2.92%in the precision rate,4.14%in the recall rate,0.0356 in the weighted harmonic mean,3.60%in the mAP@0.5 value,and a reduction in the number of parameters and complexity.Compared with the mainstream algorithm,the improved algorithm has higher detection accuracy,faster convergence speed,and better actual recognition effect,indicating the effectiveness of the improved algorithm in this paper and its potential for practical application in laboratory scenarios. | Yongliang Yang Linghua Xu Maolin Luo Xiao Wang Min Cao | 2024 | Computers, Materials & Continua2024，78，2： | 0 |
| 5 | Mechanical ventilation strategy for pulmonary rehabilitation based on patient-ventilator interaction显示文摘Mechanical ventilation is an effective medical means in the treatment of patients with critically ill,COVID-19 and other pulmonary diseases.During the mechanical ventilation and the weaning process,the conduct of pulmonary rehabilitation is essential for the patients to improve the spontaneous breathing ability and to avoid the weakness of respiratory muscles and other pulmonary functional trauma.However,inappropriate mechanical ventilation strategies for pulmonary rehabilitation often result in weaning difficulties and other ventilator complications.In this article,the mechanical ventilation strategies for pulmonary rehabilitation are studied based on the analysis of patient-ventilator interaction.A pneumatic model of the mechanical ventilation system is established to determine the mathematical relationship among the pressure,the volumetric flow,and the tidal volume.Each ventilation cycle is divided into four phases according to the different respiratory characteristics of patients,namely,the triggering phase,the inhalation phase,the switching phase,and the exhalation phase.The control parameters of the ventilator are adjusted by analyzing the interaction between the patient and the ventilator at different phases.A novel fuzzy control method of the ventilator support pressure is proposed in the pressure support ventilation mode.According to the fuzzy rules in this research,the plateau pressure can be obtained by the trigger sensitivity and the patient’s inspiratory effort.An experiment prototype of the ventilator is established to verify the accuracy of the pneumatic model and the validity of the mechanical ventilation strategies proposed in this article.In addition,through the discussion of the patient-ventilator asynchrony,the strategies for mechanical ventilation can be adjusted accordingly.The results of this research are meaningful for the clinical operation of mechanical ventilation.Besides,these results provide a theoretical basis for the future research on the intelligent control of ventilator and the automation of weaning process. | HAO LiMing LI Xiao SHI Yan CAI MaoLin REN Shuai XIE Fei LI YaNa WANG Na WANG YiXuan LUO ZuJin XU Meng | 2021 | Science China(Technological Sciences)2021，64，4： | 0 |
| 6 | Novel assisted cough system based on simulating cough airflow dynamics显示文摘Cough is a defensive behavior that protects the respiratory system from infection and clears airway secretions.Cough airflow dynamics have been analyzed by a variety of mathematical and experimental tools.In this paper,the cough airflow dynamics of 42 subjects were obtained and analyzed.An identification model based on piecewise Gauss function for cough airflow dynamics is proposed through the dimensionless method,which could achieve over 90%identification accuracy.Meanwhile,an assisted cough system based on pneumatic flow servo system is presented.The vacuum situation and feedback control are used to increase the simulated peak cough flow rate,which are important for airway secretion clearance and to avoid airway collapse,respectively.The simulated cough peak flow could reach 5 L/s without the external assistance such as manual pressing,patient cooperation and other means.Finally,the backstepping control is developed to generate a simulated cough airflow that closely mimics the natural cough airflow of humans.The assisted cough system opens up wide opportunities of practical application in airway secretion clearance for critically ill patients with COVID 2019 and other pulmonary diseases. | Shuai Ren Jinglong Niu Maolin Cai Liming Hao Yan Shi Weiqing Xu Zujin Luo | 2021 | Bio-Design and Manufacturing2021，4，3： | 0 |
| 7 | DNA repair-and nucleotide metabolism-related genes exhibit differential CHG methylation patterns in natural and synthetic polyploids (Brassica napus L.)显示文摘Polyploidization plays a crucial role in the evolution of angiosperm species.Almost all newly formed polyploids encounter genetic or epigenetic instabilities.However,the molecular mechanisms contributing to genomic instability in synthetic polyploids have not been clearly elucidated.Here,we performed a comprehensive transcriptomic and methylomic analysis of natural and synthetic polyploid rapeseeds(Brassica napus).Our results showed that the CHG methylation levels of synthetic rapeseed in different genomic contexts(genes,transposon regions,and repeat regions)were signi fi cantly lower than those of natural rapeseed.The total number and length of CHG-DMRs between natural and synthetic polyploids were much greater than those of CG-DMRs and CHH-DMRs,and the genes overlapping with these CHG-DMRs were signi fi cantly enriched in DNA damage repair and nucleotide metabolism pathways.These results indicated that CHG methylation may be more sensitive than CG and CHH methylation in regulating the stability of the polyploid genome of B.napus.In addition,many genes involved in DNA damage repair,nucleotide metabolism,and cell cycle control were significantly differentially expressed between natural and synthetic rapeseeds.Our results highlight that the genes related to DNA repair and nucleotide metabolism display differential CHG methylation patterns between natural and synthetic polyploids and reveal the potential connection between the genomic instability of polyploid plants with DNA methylation defects and dysregulation of the DNA repair system.In addition,it was found that the maintenance of CHG methylation in B.napus might be partially regulated by MET1.Our study provides novel insights into the establishment and evolution of polyploid plants and offers a potentialidea for improving the genomic stability of newly formed Brassica polyploids. | Liqin Yin Zhendong Zhu Liangjun Huang Xuan Luo Yun Li Chaowen Xiao Jin Yang Jisheng Wang Qiong Zou Lanrong Tao Zeming Kang Rong Tang Maolin Wang Shaohong Fu | 2021 | Horticulture Research2021，8，1： | 0 |
| 8 | Steering paradox for Einstein–Podolsky–Rosen argument and its extended inequality显示文摘The Einstein–Podolsky–Rosen(EPR)paradox is one of the milestones in quantum foundations,arising from the lack of a local realistic description of quantum mechanics.The EPR paradox has stimulated an important concept of“quantum nonlocality,”which manifests itself in three types:quantum entanglement,quantum steering,and Bell’s nonlocality.Although Bell’s nonlocality is more often used to show“quantum nonlocality,”the original EPR paradox is essentially a steering paradox.In this work,we formulate the original EPR steering paradox into a contradiction equality,thus making it amenable to experimental verification.We perform an experimental test of the steering paradox in a two-qubit scenario.Furthermore,by starting from the steering paradox,we generate a generalized linear steering inequality and transform this inequality into a mathematically equivalent form,which is friendlier for experimental implementation,i.e.,one may measure the observables only in the x,y,or z axis of the Bloch sphere,rather than other arbitrary directions.We also perform experiments to demonstrate this scheme.Within the experimental errors,the experimental results coincide with theoretical predictions.Our results deepen the understanding of quantum foundations and provide an efficient way to detect the steerability of quantum states. | TIANFENG FENG CHANGLIANG REN QIN FENG MAOLIN LUO XIAOGANG QIANG JING-LING CHEN XIAOQI ZHOU | 2021 | Photonics Research2021，9，6： | 0 |
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