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| 1 | The paternal epigenome and embryogenesis: poising mechanisms for development显示文摘父亲的贡献的范围长在早胚胎的开发期间被认为有限。在在整个精子发生的染色质结构的戏剧的变化被认为在 DNA 蓝图上 epigenetic 规定的复杂的层让精子空,因此把那条规定的平衡留给卵母细胞。然而, epigenetics 和男因素不孕的地里的最近的工作放了这长抓住、现在争论的教义,在一盏新灯。在发展中的精子房间调查染色质和 epigenetic 修正的漂亮研究提供了可以在发展中的胚胎为父亲的 epigenome 建立一个更关键的角色的新卓见。进染色质的 DNA methylation, histone 尾巴修正,指向的 histone 保留和鱼精朊加入在发展中的精子房间有大影响。在任何这些 epigenetic 标记的建立或维护的不安被表明了影响富饶地位,在严厉从变化对温和灾难。精子要求染色质的这个无数的结构的变化不仅在整个精子发生和未来交货起一个保护的作用到 DNA 到卵,而且,它出现,贡献未来胚胎的发展节目。这评论将集中于我们精子的 epigenetics 的当前的理解。我们将讨论导致对开发必要的基因在胚胎的开发,其混乱可以导致减少的肥沃早为激活被平衡的精子特定的染色质修正。 | Timothy G Jenkins Douglas T Carrell | 2011 | Asian Journal of Andrology2011，13，1： | 14 |
| 2 | Finding drug targets in microbial genomes 显示文摘 | Timothy D R Steven R G Herve T | 2001 | Res Focus2001，6，17： | 1 |
| 3 | Transparent conducting Nnc oxide thin films doped with aluminum and molybdenum显示文摘 | JOEL N D TIMOTHY A G DAVID M W TERESA M B MATTHEW Y BOBBY T TIMOTHY J C | 2007 | Journal V-acuum Society Technology2007，25，4： | 1 |
| 4 | Suboptimal Minimum Cluster Volume Cover-Based Method for Measuring Fractal Dimension显示文摘 | Charles R T Timothy R M David J G | 2003 | IEEE Transactions on Geoscience and Remote Sensing2003，25，1： | 1 |
| 5 | Marine tourism resource development in korea显示文摘 | TIMOTHY T KIM S G CHANG Y T | 1999 | Marine Resource Economics1999，14，2： | 1 |
| 6 | Comparative approaches for assessing network vulnerability显示文摘 | Tony H G Timothy C M Alan T M | 2008 | International Regional Science Review2008，31，1： | 1 |
| 7 | 17 β-estradiol acts directly on the clonal osteoblastic cell line UMR 106显示文摘 | GRAY T K TIMOTHY C F KATHLEEN M G | 1987 | Proc Natl Acad Sci1987，84，17： | 1 |
| 8 | Characterization of Lead Leachability from CathodeRay Tubes Using the Toxicity Characteristic LeachingProcedure显示文摘 | MUSSON S E JANG Y C TIMOTHY G T | 2000 | Environmental Science &- Technology2000，34，20： | 1 |
| 9 | Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (NBNP) concentrations显示文摘 | RICHARD W T CHRIDTOPHER M F TIMOTHY G Y | 2000 | Lancet2000，355，： | 1 |
| 10 | Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies显示文摘 | Stacey A S Timothy J G David M T | 2006 | Brain Research2006，1085，： | 1 |
| 11 | Impact of thrombolysis, intra-aortic balloon pump counterpulsation, and their combination in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry显示文摘 | Timothy A Sanborn Lynn A Sleeper Eric R Bates Alice K Jacobs Jean Boland John K French Jo Dens Vladimir Dzavik Sebastian T Palmeri John G Webb Mark Goldberger Judith S Hochman | 2000 | Journal of the American College of Cardiology2000，，： | 1 |
| 12 | Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide(N-BNP) concentrations显示文摘 | Richard W T Chridtopher M F Timothy G Y | 2000 | Lancet2000，355，： | 1 |
| 13 | The stretta procedure for the treatment of GERD:6 and 12 month follow-up of the U S open label trial 显示文摘 | Tfiadafilopoulos G John DB Timothy T | 2002 | Gastrointestinal Endoscopy2002，55，： | 1 |
| 14 | Drought resistance of two hybrid Populus clones grown in a largescale plantation显示文摘 | Timothy J T Tuskan G A Gebre G M | 1998 | Tree Physiology1998，，18： | 1 |
| 15 | Computational design of hypervelocity launchers 显示文摘 | Timothy G T Chhabildas L C | 1995 | Int J Impact Eng1995，17，456： | 1 |
| 16 | Drought resistance of two hybrid populus clones grown in a large scale plantation显示文摘 | Timothy J T Tuskan G A Gebre G M | 1998 | Tree Physiol1998，18，： | 1 |
| 17 | Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry 显示文摘 | Wei T Lloyd MS | 1997 | Nature Biotec1997，15，： | 1 |
| 18 | A highly emissive heteroleptie copper( Ⅰ ) bis(phenanthroline) complex: ^+ ( dbp = 2, 9-di-t-butyl- 1,10-phenanthroline, dmp = 2,9-dimethyl-1,10-phenan- throline) 显示文摘 | MARK T M PETER K G TIMOTHY B K | 1999 | Journal of American Chemical Society1999，121，： | 1 |
| 19 | Effect of short-term hor- mone replacement therapy on ovary cancer risk reduction after bilateral prophylactic oophorectomy in hormone Replacement Qvariectomy mutation carriers显示文摘 | Eeles D G Timothy R Rebbeck T | 2005 | Qfficai journal of the American Society of Clinical Oncology2005，23，31： | 1 |
| 20 | Southern Ocean iron enrichment experiment: Carbon cycling in high-and low-Si waters 显示文摘 | Coale K H Johnson K S Chavez F P Buesseler K O Barber R T Brzezinski M A Cochlan W P Millero F J Falkowski P G Bauer J E Wanninkhof R H Kudela R M Altabet M A Hales B E Takahashi T Landry M R Bidigare R R Wang Xiujun Chase Z Strutton P G Friederich G E Gorbunov M Y Lance V P Hilting A K Hiscock M R Demarest M Hiscock W T Sullivan K F Tanner S J Gordon R M Hunter C N Elrod V A Fitzwater S E Jones J L Tozzi S Koblizek M Roberts A E Herndon J Brewster J Ladizinsky N Smith G Cooper D Timothy D Brown S L Selph K E Sheridan C C Twining B S Johnson Z I | 2004 | Science2004，304，5669： | 1 |
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