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| 1 | Diversity of fungi,bacteria andactinomycetes on leaves decomposingin a stream显示文摘 | Mitali D Todd V R Laura G L | 2007 | Applied andEnvironmental Microbiology2007，73，3： | 1 |
| 2 | Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain 显示文摘 | Raghavendra R V L Dogan A Todd K G | 2001 | J Neurosci2001，21，6： | 1 |
| 3 | Diversity of fungi,bacteria,andactinomycetes on leaves decomposing in a stream显示文摘 | Mitali D Todd V R Laura G L | 2007 | Applied andEnvironmental Microbiology2007，73，3： | 1 |
| 4 | Anaerobic di- gestion of processed municipal solid waste using a novel high solids reactor: maximum solids levels and mixing re- quirements 显示文摘 | Christopher J R Michael E H Todd B V | 1990 | Biotechnology Letters1990，12，3： | 1 |
| 5 | Diagnosis of duck circovirus infections by conventional and real-time polymerase chain reaction tests显示文摘 | Fringuelli E Scott A N Beckett A McKillen J Smyth JA Palya V Glavits R Ivanics E Mankertz A Franciosini MP Todd D | 2005 | Avian Pathol2005，34，6： | 1 |
| 6 | Endothelial function testing as a biomarker of vascular disease 显示文摘 | Subodh V Michae R B Todd J A | 2003 | Circulation2003，108，17： | 1 |
| 7 | Regional blood-brain barrier permeability changes after restoration of blood flow in postischemic gerbil brains:a quantitative study 显示文摘 | PICOZZI P R TODD N V CROCKARD H A | 1985 | J Cereb Blood Flow Metab1985，5，1： | 1 |
| 8 | Surgical out-come in rheumatoid ranawat class 11I b myelopathy 显示文摘 | NANNAPANENI R BEHARI S TODD N V | 2005 | Neurosurgery2005，56，4： | 1 |
| 9 | Behavioral Modeling of a Switched Reluctance Generator for Aircraft Power Systems显示文摘 | Valdivia V Todd R Frank J | 2014 | IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS2014，61，6： | 1 |
| 10 | Cerebral blood flow in the four-vessel occlusion rat model 显示文摘 | Todd N V Crockard H A Russel R W | 1984 | Stroke1984，15，3： | 1 |
| 11 | Significance and petrogenesis of mylonite records显示文摘 | Tullis J Snoke A W Todd V R | 1982 | Geology1982，10，： | 1 |
| 12 | Implicit versus explicit attitudes toward psychiatric medication:Implicatiom for insight and treatment adherence显示文摘 | Rusch N Todd A R Bodenhausenc G V | 2009 | Schizophrenia Research2009，112，： | 1 |
| 13 | Perspective taking combats automatric expressions of racial bias显示文摘 | Todd R Bodenhausen G V Richeson J A | 2011 | Journal of personality and social psychology2011，100，6： | 1 |
| 14 | Implicit versus explicit at- titudes toward psychiatric medication:Implications for insight and treat- ment adherence显示文摘 | Rtsch N Todd A R Bodenhausen G V | 2009 | Schizophr Res2009，112，1： | 1 |
| 15 | Guar gum and similar soluble fiber in the regulation of cholesterol metabolism: Current understandings and future research priorities显示文摘 | TODD C R SCOTT V H PETER JH J | 2008 | Vasc Health Risk Manag2008，4，5： | 1 |
| 16 | 颅内动脉粥样硬化血管内治疗的实践标准显示文摘背景有症状颅内动脉粥样硬化性疾病(intraeranial atherosclerotic disease,ICAD)是全世界范围内最常见的卒中原因之一。研究显示,严重ICAD患者的复发性卒中风险很高,亟需有效的预防手段。药物治疗是治疗ICAD的基础,对所有患者都至关重要。血管内治疗也是一种潜在的治疗选择,但在最佳的技术和患者选择方面仍需进一步探索。本指南旨在为ICAD患者提供诊断和血管内治疗的推荐意见。方法进行文献回顾,以选#2000年至2011年期间发表的有关ICAD的文献。根据美国心脏协会(AmericanHeartAssociation,AHA)庄荚国卒中协会标准对证据进行评估和分类。在神经介入外科学学会标准委员会对现有证据进行评价的基础上制定推荐意见。按照美国神经病学学会(AmericanAcademyofNeurology,AAN)、AHA卒中委员会以及牛津大学循证医学中心(CentreforEvidenceBasedMedicine,CEBM)建议的循证医学指南进行评估。结果总共选定59篇文献。支架置人术与强化药物治疗预防颅内动脉狭窄患者复发性卒中(StentingversusAggressiveMedicalManagementforPreventingRecurrentStrokeinIntracranial&enosis。SAMMPRIS)研究是现有的唯一一项前瞻性随机对照试验,文献的证据级别被归类为AHA B级、AANⅡ级和CEBM1b级。有症状椎动脉或颅内动脉粥样硬化性疾病支架置人术(StentingofSymptomaticAtheroscleroticLesionsintheVertebralorIntracranialarteries,SSYLVtA)试验是由独立的神经科医生进行转归评价的一项前瞻性非随机研究,文献的证据级别被归类为AHAB级、AANⅢ级和CEBM2级。其他研究均为非对照性或未进行客观的转归评价,因此证据级别被归类为AHAC级、AAHIV级和CEBM4级。结论对于有症状ICAD患者,阿司匹林+氯毗格雷联合治疗3个月和强化控制危险因素是一线治疗方案。对于经过选择的有症状ICAD患者,球囊血管成形/支架置入术是一种可供选择的治疗方案。需要进一步研究,以确定合适的患者选择标准以及针对各种亚组患者的最佳治疗方案。 | M Shazam Hussain Justin F Fraser Todd Abruzzo Kristine A Blackham Ketan R Bulsara Colin P Derdeyn Chirag D Gandhi Joshua AHksch Daniel P Hsu Mahesh V Jayaraman Philip M M eYers Sandra Narayanan Charles J Prestigiacomo Peter A Rasmussen 蔡乾昆(译) 李永坤(译) 刘新峰(译) | 2012 | 国际脑血管病杂志2012，20，12： | 1 |
| 17 | Anaerobic digestion of processed municipal solid waste using a novel high solids reactor:maximum solids levels and mixing requirements显示文摘 | Christopher J R Michael E H Todd B V | | 0，，03： | 1 |
| 18 | Diversity of fungi, bacteri- a, and actinomyeetes on leaves decomposing in a stream 显示文摘 | MITALI D TODD V R LAURA G L | 2007 | Ap- plied and Environmental Microbiology2007，73，： | 1 |
| 19 | Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases in children and adolescents.NAFLD ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis(NASH),wherein hepatocellular inflammation and/or fibrosis coexist with steatosis.Circulating microRNA(miRNA)levels have been suggested to be altered in NAFLD,but the extent to which miRNA are related to NAFLD features remains unknown.This analysis tested the hypothesis that plasma miRNAs are significantly associated with histological features of NAFLD in adolescents.AIM To investigate the relationship between plasma miRNA expression and NAFLD features among adolescents with NAFLD.METHODS This study included 81 adolescents diagnosed with NAFLD and 54 adolescents without NAFLD from the Teen-Longitudinal Assessment of Bariatric Surgery study.Intra-operative core liver biopsies were collected from participants and used to characterize histological features of NAFLD.Plasma samples were collected during surgery for miRNA profiling.A total of 843 plasma miRNAs were profiled using the HTG EdgeSeq platform.We examined associations of plasma miRNAs and NAFLD features using logistic regression after adjusting for age,sex,race,and other key covariates.Ingenuity Pathways Analysis was used to identify biological functions of miRNAs that were associated with multiple histological features of NAFLD.RESULTS We identified 16 upregulated plasma miRNAs,including miR-193a-5p and miR-193b-5p,and 22 downregulated plasma miRNAs,including miR-1282 and miR-6734-5p,in adolescents with NAFLD.Moreover,52,16,15,and 9 plasma miRNAs were associated with NASH,fibrosis,ballooning degeneration,and lobular inflammation,respectively.Collectively,16 miRNAs were associated with two or more histological features of NAFLD.Among those miRNAs,miR-411-5p was downregulated in NASH,ballooning,and fibrosis,while miR-122-5p,miR-1343-5p,miR-193a-5p,miR-193b-5p,and miR-7845-5p were consistently and positively associated with all histological features of NAFLD.Pathway analysis revealed that most common pathways of miRNAs associated with multiple NAFLD features have been associated with tumor progression,while we also identified linkages between miR-122-5p and hepatitis C virus and between miR-199b-5p and chronic hepatitis B.CONCLUSION Plasma miRNAs were associated with NAFLD features in adolescent with severe obesity.Larger studies with more heterogeneous NAFLD phenotypes are needed to evaluate miRNAs as potential biomarkers of NAFLD. | Yi-Jie Li Brittney O Baumert Nikos Stratakis Jesse A Goodrich Hao-Tian Wu Jing-Xuan He Yin-Qi Zhao Max T Aung Hong-Xu Wang Sandrah P Eckel Douglas I Walker Damaskini Valvi Michele A La Merrill Justin R Ryder Thomas H Inge Todd Jenkins Stephanie Sisley Rohit Kohli Stavra A Xanthakos Andrea A Baccarelli Rob McConnell David V Conti Lida Chatzi | 2024 | World Journal of Gastroenterology2024，30，4： | 0 |
| 20 | 破裂和未破裂颅内动脉瘤栓塞治疗实践标准显示文摘弹簧圈栓塞最初被设计并经美国食品药品监督管理局批准用于治疗显微外科手术夹闭风险高的脑动脉瘤,但目前该方法越来越被认为是颅内动脉瘤的一线治疗方法。动脉瘤血管内治疗技术已有长足进步,新器材的研发使得以前因血管解剖结构复杂而无法填塞的动脉瘤也得以治疗,从而扩大了血管内治疗的适应证。而且,血管内弹簧圈栓塞已成为当前动脉瘤血管内治疗的主流方法;医学文献证明,在特定患者人群中,弹簧圈栓塞的转归优于外科手术夹闭。最近的一份美国心脏协会(AmericanHeartAssociation,AHA)科学声明指出,对于适合治疗的脑动脉瘤,不论是血管内栓塞还是显微外科手术夹闭,均为破裂动脉瘤I级推荐治疗方法和未破裂动脉瘤的11a级推荐治疗方法。在这两组患者中,治疗利大于弊。一个在血管显微神经外科、神经重症监护和介入神经外科方面有着丰富经验的多学科团队最有利于对颅内动脉瘤的处理实施最佳的技术。神经血管联合写作组此前已发表过一份联合声明,提出了有关脑血管介入治疗的培训和认证的推荐意见。 | Athos Patsalides Ketan R Bulsara Daniel P Hsu Todd Abruzzo Sandm Narayanan Mahesh V Jayaraman Gary Duckwiler Richard Paul Klucznik Michael Kelly Joshua A Hirsch Don Heck Jeffery Stmshine Don Frei Michael J Alexander Huy M Do Philip M Meyers 邱忠明(译) 张君(译) 徐格林(译) | 2013 | 国际脑血管病杂志2013，21，6： | 0 |
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