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301篇 您的检索式:作者名="Takeuchi K A"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Neonatal repair of right interrupted aortic arch with cerebro-myocardial perfusion technique显示文摘Takeuchi K Masuzawa A Kohayashi J 2011Interact Cardiovasc Thorac Surg2011,13,4:1
3Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid ceils显示文摘Okuda S Tsutsui H Shiina K Sprunck S Takeuchi H Yui R Kasahara R D HamamuraY Mizukami A S usaki D Kawano N Sakakibara T Namiki S Itoh K Otsuka K Matsuzaki M Nozaki H Kuroiwa T Nakano A Kanaoka M M Dresselhaus T Sasaki N Higashiyama T 0,,7236:1
4Feasibility and validity of the Patient Neurotoxicity Questionnaire during taxane chemotherapy in a phase Ⅲ randomized trial in patients with breast cancer:N-SAS BC 02显示文摘Shimozuma K Ohashi Y Takeuchi A 0,,12:1
5A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species显示文摘Nakamura A Arimoto M Takeuchi K 2002Biological and''Pharmaceutical Bulletin2002,25,5:1
6Calcium apatite prepared from calium hydroxide and orthophosphoric acid 显示文摘Osaka A Miura Y Takeuchi K 1991J Mater Sci:Mater Med1991,2,:1
7A versatile method of identifying specific binding proteins on affinity resins显示文摘Yamamoto K Yamazaki A Takeuchi M 2006Anal Bioch2006,352,1:1
8Expression of CD44 variant exons 8~10 incolorectal cancer and its relationship to metastasis显示文摘Takeuchi K Yamaguchi A Urano T 1995Jpn J Cancer Res1995,86,:1
9Taxane-induced peripheral neuropathy and health-related quality of life in postoperative breast cancer patients undergoing adiuvant chemotherapy: N-SAS BC 02, a randomized clinical trial 显示文摘Shimozuma K Ohashi Y Takeuchi A 2012Support Care Cancer2012,20,12:1
10F requeney scale for symptom of gastroesophageal reflux disease predicts the need for addition of prokinetics to proton inhibitor therapy显示文摘M iyamoto M Hurum a K Takeuchi K et el 2008J G as- troenteroIH epatoI2008,23,5:1
11Age-related amy- loid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuro- nal loss显示文摘Takeuchi A Irizarry MC Duff K 2000Am J Pathol2000,157,1:1
12Advanced lithium batteries for implantable medical devices:mechanistic study of SVO cathode synthesis显示文摘Takeuchi K J Leising R A Palazzo M J 2003Journal of Power Sources2003,119,121:1
13Aspolin,a novel extremely aspartic acid-rich protein in fish muscle,promotes iron-mediated demethylation of trimethylamine-N-oxide显示文摘TAKEUCHI K HATANAKA A KIMURA M 2003J Biol Chem2003,278,47:1
14Gastric mucosal defense and cytoprotection:bench to bedside显示文摘Laine L Takeuchi K Tarnawski A 0,,01:1
15Gastric mucosal defense and cytoprotection:bench to bedside显示文摘Laine L Takeuchi K Tarnawski A 0,,01:1
16查看详情显示文摘Takeuchi K J M arschilok A C Davis SM eta 1 0,,:1
17Transcriptional suppression of type 1 angiotensin Ⅱreceptor gene expression by peroxisome proliferator activated receptor-γ in vascular smooth muscle cells显示文摘Sugawara A Takeuchi K Uruno A 2001Endocrinology2001,142,:1
18Differential effects among thiazolidines on the transcription of thromboxane receptor and angiotension Ⅱtype 1 receptor genes显示文摘SUGAWARA A TAKEUCHI K URUNO A 2001Hypertens Res2001,24,3:1
19Differential effects among thiazolidinedione on the transcription of thromboxane receptor and angiotensin II type 1 receptor genes显示文摘Sugawara A Takeuchi K Uruno A 2001Hypertins Res2001,24,:1
20Surgical outcome of heterotaxy syndrome in a single institution 显示文摘Takeuchi K Murakami A Hirata Y 2006Asian Cardio- vasc Thorac Ann2006,14,:1
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