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| 1 | Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study显示文摘AIM To treated with electrochemotherapy(ECT) a prospective case series of patients with liver cirrhosis and Vp3-Vp4- portal vein tumor thrombus(PVTT) from hepatocellular carcinoma(HCC), in order to evaluate the feasibility, safety and efficacy of this new non thermal ablative technique in those patients. METHODS Six patients(5 males and 1 female), aged 61-85 years(mean age, 70 years), four in Child-Pugh A and two in Child-Pugh B class, entered our study series. All patients were studied with three-phase computed tomography(CT), contrast enhanced ultrasound(CEUS) and ultrasound-guided percutaneous biopsy of the thrombus before ECT. All patients underwent ECT treatment(Cliniporator Vitae?, IGEA Sp A, Carpi, Modena, Italy) of Vp3-Vp4 PVTT in a single session. At the end of the procedure a post-treatment biopsy of the thrombus was performed. Scheduled follow-up in all patients entailed: CEUS within 24 h after treatment; triphasic contrastenhanced CT and CEUS at 3 mo after treatment and every six months thereafter.RESULTS Post-treatment CEUS showed complete absence of enhancement of the treated thrombus in all cases. Post-treatment biopsy showed apoptosis and necrosis of tumor cells in all cases. The follow-up ranged from 9 to 20 mo(median, 14 mo). In 2 patients, the followup CT and CEUS demonstrated complete patency of the treated portal vein. Other 3 patients showed a persistent avascular non-tumoral shrinked thrombus at CEUS and CT during follow-up. No local recurrence was observed at follow-up CT and CEUS in 5/6 patients. One patient was lost to follow-up because of death from gastrointestinal hemorrage 5 wk after ECT. CONCLUSION In patients with cirrhosis, ECT seems effective and safe for curative treatment of Vp3-Vp4 PVTT from HCC. | Luciano Tarantino Giuseppina Busto Aurelio Nasto Raffaele Fristachi Luigi Cacace Maria Talamo Catello Accardo Sara Bortone Paolo Gallo Paolo Tarantino Riccardo Aurelio Nasto Matteo Nicola Dario Di Minno Pasquale Ambrosino | 2017 | World Journal of Gastroenterology2017，23，5： | 7 |
| 2 | Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion显示文摘 | Bonaldi T Talamo F Scaffidi P | | 0，，20： | 1 |
| 3 | Comparative proteomic analysis of mammalian animal tissues and body fluids:bovine proteome database显示文摘 | Amhrosio Chiara D' Arena Simona Talamo Fabio | 2005 | Journal of Chromatography B2005，815，： | 1 |
| 4 | Late traumatic dislocation of laser in situkeratomileusis corneal flaps显示文摘 | Melki SA Talamo JH Demetriades AM | 2000 | Ophthalmology2000，107，： | 1 |
| 5 | Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion显示文摘 | Bonaldi T Talamo F Scaffidi P | 2003 | EMBO J2003，22，20： | 1 |
| 6 | Late traumatic dislocation of laser in situ keratomileusis corneal flaps显示文摘 | Melki SA Talamo JH Demetriades AM | 2000 | Ophthalmology2000，107，12： | 1 |
| 7 | Monocytic cells hypemcetylate chmmatin protein HMGB1 to redirect it towards secretion显示文摘 | Bonaldi T Talamo F Scaffidi P | 2003 | EMBOJ2003，22，20： | 1 |
| 8 | Metabolic syndrome in psychiatrically hospitalized patients treated with antipsychotics and other psychotropics 显示文摘 | Centorrino F Masters GA Talamo A | 2012 | Hum Psychopharmacol2012，27，： | 1 |
| 9 | Health status perce- ption and airflow obstruction in five Latin American cities: the PLATINO study显示文摘 | Montes-de-Oca M Talamo C Halbert RJ | 2009 | Respir-Med2009，103，9： | 1 |
| 10 | Algorithms for the re- laxed online bin-packing model 显示文摘 | Garnbosi G Postiglione A Talamo M | 2000 | SIAM Journal on Compu- ting2000，30，5： | 1 |
| 11 | Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin Cand steroids显示文摘 | Talamo JH Gollamudi S Green WR | 1991 | Arch Ophthalmol1991，109，4： | 1 |
| 12 | Monocytic cells hyper-acetylate chromatin protein HMGB1 to redirect it towards secretion显示文摘 | BONALDI T TALAMO F SCAFFIDI P | 2003 | Embo J2003，22，20： | 1 |
| 13 | Diagnostic labeling of COPD in five Latin American cities显示文摘 | Talamo C de Oca M M Halbert R | 2007 | Chest2007，131，1： | 1 |
| 14 | The influence of aminoglycoside antibiotics显示文摘 | Jonathan H Talamo AB Donald JD | 1985 | Am J Ophthalmol1985，100，7： | 1 |
| 15 | Beyond the CRAB symptoms:a study of presenting clinical manifestations of multiple myeloma显示文摘 | Talamo G Farooq U Zangari M | | 0，，： | 1 |
| 16 | Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion显示文摘 | BONALDI T TALAMO F SCAFFIDI P | 2003 | EMBOJ2003，22，20： | 1 |
| 17 | Tenofovir and its potential in the treatment of hepatitis B virus 显示文摘 | Reynaud L Carleo MA Talamo M | 2009 | Ther Clin Risk Manag2009，5，1： | 1 |
| 18 | Tenofovir andits potential in the treatment of hepatitis B virus显示文摘 | Reynaud L Carleo MA Talamo M | 2009 | Ther Clin Risk Manag2009，5，3： | 1 |
| 19 | Algorithms for the On-Line Travelling Salesman 1显示文摘 | G. Ausiello E. Feuerstein S. Leonardi L. Stougie M. Talamo | 2001 | Algorithmica2001，，4： | 1 |
| 20 | Proteins from bovine tissues and biological fluids:defining a reference electrophoresis map for liver,kidney,muscle,plasma and red blood cells显示文摘 | TALAMO F D'AMBROSIO C ARENA S | 2003 | Proteomics2003，3，： | 1 |
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