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| 1 | Successful resection of metachronous para-aortic, Virchow lymph node and liver metastatic recurrence of rectal cancer显示文摘A 66-year-old female presented with the main complaint of defecation trouble and abdominal distention. With diagnosis of rectal cancer, c SS, c N0, c H0, c P0, c M0 c Stage Ⅱ, Hartmann's operation with D3 lymph node dissection was performed and a para-aortic lymph node and a disseminated node near the primary tumor were resected. Histological examination showed moderately differentiated adenocarcinoma, p SS, p N3, p H0, p P1, p M1(para-aortic lymph node, dissemination) f Stage Ⅳ. After the operation, the patient received chemotherapy with FOLFIRI regimen. After 12 cycles of FOLFIRI regimen, computed tomography(CT) detected an 11 mm of liver metastasis in the posteroinferior segment of right hepatic lobe. With diagnosis of liver metastatic recurrence, we performed partial hepatectomy. Histological examination revealed moderately differentiated adenocarcinoma as a metastatic rectal cancer with cut end microscopically positive. After the second operation, the patient received chemotherapy with TS1 alone for 2 years. Ten months after the break, CT detected a 20 mm of paraaortic lymph node metastasis and a 10 mm of lymph node metastasis at the hepato-duodenal ligament. With diagnosis of lymph node metastatic recurrences, we performed lymph node dissection. Histological examination revealed moderately differentiated adenocarcinoma as metastatic rectal cancer in paraaortic and hepato-duodenal ligament areas. After the third operation, we started chemotherapy with modified FOLFOX6 regimen. After 2 cycles of modified FOLFOX6 regimen, due to the onset of neutropenia and liver dysfunction, we switched to capecitabine aloneand continued it for 6 mo and then stopped. Eleven months after the break, CT detected two swelling 12 mm of lymph nodes at the left supraclavicular region. With diagnosis of Virchow lymph node metastatic recurrence, we started chemotherapy with capecitabine plus bevacizumab regimen. Due to the onset of neutropenia and hand foot syndrome(Grade 3), we managed to continue capecitabine administration with extension of interval period and dose reduction. After 2 years and 2 mo from starting capecitabine plus bevacizumab regimen, Virchow lymph nodes had slowly grown up to 17 mm. Because no recurrence had been detected besides Virchow lymph nodes for this follow up period, considering the side effects and quality of life, surgical resection was selected. We performed left supraclavicular lymph node dissection. Histological examination revealed moderately differentiated adenocarcinoma as a metastatic rectal cancer. After the fourth operation, the patient selected follow up without chemotherapy. Now we follow up her without recurrence and keep her quality of life high. | Nobuyoshi Takeshita Toru Fukunaga Masayuki Kimura Yuji Sugamoto Kentaro Tasaki Isamu Hoshino Takumi Ota Tetsuro Maruyama Tomohide Tamachi Takashi Hosokawa Yo Asai Hisahiro Matsubara | 2015 | World Journal of Gastroenterology2015，21，44： | 4 |
| 2 | Esophageal intramural pseudodiverticulosis of the residual esophagus after esophagectomy for esophageal cancer显示文摘A 91-year-old man was referred to our hospital with intermittent dysphagia. He had undergone esophagectomy for esophageal cancer(T3N2M0 Stage Ⅲ) 11 years earlier. Endoscopic examination revealed an anastomotic stricture; signs of inflammation,including redness,erosion,edema,bleeding,friability,and exudate with white plaques; and multiple depressions in the residual esophagus. Radiographical examination revealed numerous fine,gastrografinfilled projections and an anastomotic stricture. Biopsy specimens from the area of the anastomotic stricture revealed inflammatory changes without signs of malignancy. Candida glabrata was detected with a culture test of the biopsy specimens. The stricture was diagnosed as a benign stricture that was caused by esophageal intramural pseudodiverticulosis. Accordingly,endoscopic balloon dilatation was performed and antifungal therapy was started in the hospital. Seven weeks later,endoscopic examination revealed improvement in the mucosal inflammation; only the pseudodiverticulosis remained. Consequently,the patient was discharged. At the latest follow-up,the patient was symptomfree and the pseudodiverticulosis remained in the residual esophagus without any signs of stricture or inflammation. | Nobuyoshi Takeshita Naoki Kanda Toru Fukunaga Masayuki Kimura Yuji Sugamoto Kentaro Tasaki Masaya Uesato Tetsutaro Sazuka Tetsuro Maruyama Naohiro Aida Tomohide Tamachi Takashi Hosokawa Yo Asai Hisahiro Matsubara | 2015 | World Journal of Gastroenterology2015，21，30： | 2 |
| 3 | IL-25 enhances allergic airway inflammation by amplifying a Th2 dependent pathway in mice显示文摘 | Tamachi T | 2006 | J Allergy Clin lrnmunol2006，118，3： | 1 |
| 4 | Endoscopic occlusion with silicone spigots for the closure of refractory esophago-bronchiole fistula after esophagectomy显示文摘A 65-year-old man with c T1 b N0M0 stage Ⅰ middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred,but it spontaneously improved. At six months after the operation,he was rehospitalized with a cough and dysphagia. An esophago-bronchiole fistula and stenosis of the gastric tube were observed. He first underwent stent placement in the gastric tube. Two weeks later,the syringeal epithelium was burned by argon plasma coagulation after stent removal. Endoscopic occlusion was then performed for the fistula with two guidewire-assisted silicone spigots. Two weeks later,he was discharged on an oral diet,and he has not developed recurrence of the fistula or cancer for three years. This is the first report of endoscopic occlusion with a guidewire-assisted silicone spigot through the esophagus. | Masaya Uesato Tsuguaki Kono Yasunori Akutsu Kentarou Murakami Akiko Kagaya Yorihiko Muto Akira Nakano Mizuho Aikawa Tomohide Tamachi Hiroyuki Amagai Takahiro Arasawa Yasuhide Muto Hisahiro Matsubara | 2017 | World Journal of Gastroenterology2017，23，28： | 1 |
| 5 | IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | J Allergy Clin Immunol2006，118，3： | 1 |
| 6 | IL-25 enhances allergic airway inflammation by amplifying a Th2 celldependent pathway in mice 显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | J Allergy Clin Immunol2006，118，： | 1 |
| 7 | IL-25 enhances allergic airway inflammation by amplifying a T H 2 cell–dependent pathway in mice显示文摘 | Tomohiro Tamachi Yuko Maezawa Kei Ikeda Shin-ichiro Kagami Masahiko Hatano Yohei Seto Akira Suto Kotaro Suzuki Norihiko Watanabe Yasushi Saito Takeshi Tokuhisa Itsuo Iwamoto Hiroshi Nakajima | 2006 | The Journal of Allergy and Clinical Immunology2006，，3： | 1 |
| 8 | IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | J Allergy Clin Immunol2006，118，3： | 1 |
| 9 | IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | Allergy Clin Immunol2006，118，3： | 1 |
| 10 | IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice显示文摘 | Tamachi T Maezawa Y Ikeda K | | 0，，03： | 1 |
| 11 | IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice显示文摘 | TAMACHI T MAEZAWA Y IKEDA K | 2006 | J Allergy Clin Immunol2006，118，3： | 1 |
| 12 | Effects of carvedilol on serum lipids in patients with essential hypertension显示文摘 | Goto Y Tamachi H Fusegawa Y | 1991 | J Cardiovasc Pharmacol1991，18，： | 1 |
| 13 | Effects of carvedilol on serum lipids in patients with essential hypertension显示文摘 | Goto Y Tamachi H Pusegawa Y | 1991 | Cardiovasc Phamacol1991，18，4： | 1 |
| 14 | Interleukin 25 in allergic airway inflammation显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | Int Arch Allergy Immunol2006，1401，： | 1 |
| 15 | IL-25 enhances allergic airway inflammation by amplifying a TH2 cell dependent pathway in mice显示文摘 | Tamachi T Maezawa Y Ikeda K | 2006 | J Allergy Clin Immunol2006，118，3： | 1 |
| 16 | Interleukin 25 in allergic airway inflammation显示文摘 | Tamachi T Maezawa Y lkeda K | 2006 | Int Arch Allergy Immunol2006，140，： | 1 |
| 17 | Effects of carvedilol in serum lipids in patients with essential hypertension显示文摘 | Goto Y Tamachi H Fusegawa Y | 1991 | J Cardiovasc Pharmacol1991，18，4： | 1 |
| 18 | Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway infammafion 显示文摘 | Furuta S Kagami S Tamachi T | 2008 | J Immunol2008，180，： | 1 |
| 19 | The effect of CS-514 on serum lipids and apolipoproteins in hypercholesterolemic subjects 显示文摘 | Nakaya N Homma Y Tamachi H | 1987 | JAMA1987，257，22： | 1 |
| 20 | Interfacial reaction behavior and thermal stability of barium zirconate coated alumina fiber/alumina matrix composites显示文摘 | Chen Z Tamachi T Kulkarni R | 2008 | J Euro Ceram Soc2008，28，： | 1 |
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