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		题名	作者	年代	出处	被引量
	1	The Inhibitory Effect of Somatostatin Analogue RC-160 on the Growth of Endometrial Carcinoma Cell Line HEC-1A显示文摘Objective:To evaluate the inhibitory effect of somatostatin analogue RC-160 on the growth of human endometrial cancer cells (HEC-1A) in vitro.Method:RT-PCR was used to examine the existence of somatostatin receptors on the HEC-1A cells. The anti-proliferative effect of RC-160 on the growth of HEC-1A cells was detected by using BrdU incorporation test.TUNEL staining was used to find out whether apoptosis was involved in the inhibitory process.Result:All the five somatostatin receptor subtypes were demonstrated in HEC-1A cells.RC-160 reduced the HEC-1A cell growth stimulated by serum in a dose-dependent manner.The effect was maximal at the concentration of 10 -5 M after 48 hours’ treatment.No apoptosis was detected.Conclusion:Somatostatin analogue RC-160 can inhibit the proliferation of endometrial carcinoma cell line HEC-1A through binding to the somatostatin receptors on the cells.It seems that apoptosis is not mainly responsible for the inhibition.	LiangRui TangXiaohui ZhuGaixia GaoYane GuoYin	2004	现代妇产科进展2004，13，3：	0

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