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| 1 | Intraductal papillary mucinous neoplasm and the pancreatic incidentaloma显示文摘Asymptomatic pancreatic lesions(APL) are a commonly encountered problem in today's pancreatic surgical practices.Current literature regarding etiologies and incidence of APLs,particularly intraductal papillary mucinous neoplasm(IPMN),is presented.APLs constitute a wide spectrum of pathology(solid/cystic,benign/premalignant/malignant) but,overall,IPMN is now the most common diagnosis.The Sendai Guidelines and their function as a basis for risk stratification in branch duct IPMN are presented.The importance of traditionally analyzed cyst characteristics including size,presence of mucin or nodules and cyst fluid aspirate as indicators of malignancy is emphasized,noting also the potential correlation of main duct dilatation,thickened septae and elevated cyst fluid CEA with increased risk of malignancy.Current complication rates after resection of APLs are reviewed and found to be generally equivalent to those for symptomatic resections.A potential multidisciplinary treatment strategy is offered considering the costs of surgery versus repeated imaging or follow up endoscopy for these lesions.The decision for intervention is ultimately based on the Sendai Guidelines in the context of the individual patient. | Tara S Kent Charles M Vollmer Jr Mark P Callery | 2010 | World Journal of Gastrointestinal Surgery2010，2，10： | 3 |
| 2 | 接受他汀治疗患者新发糖尿病风险:人群为基础的研究显示文摘目的 研究接受HMG-CoA还原酶抑制剂(他汀类药物)治疗的患者的新发糖尿病风险。设计 人群为基础的队列研究,以时间事件分析的方法评估各种他汀类药物应用和新发糖尿病风险的相关性分析。计算危害比(hazard ratios,HR)来确定他汀的种类及剂量与新发糖尿病的关系。 | Aleesa A Caner Tara Gomes Ximena Camacho David N Juurlink Baiju R Shah Muhammad M Mamdani 张秀珍(译) 骆斯慧(译) 翁建平(校) | 2013 | 英国医学杂志中文版2013，16，5： | 2 |
| 3 | Pharmacological inhibition of diacylglycerol acyltransferase-1 and insights into postprandial gut peptide secretion显示文摘AIM To examine the role that enzyme Acyl-CoA:diacylglycerol acyltransferase-1(DGAT1) plays in postprandial gut peptide secretion and signaling.METHODS The standard experimental paradigm utilized to evaluate the incretin response was a lipid challenge.Following a lipid challenge,plasma was collected via cardiac puncture at each time point from a cohort of 5-8 mice per group from baseline at time zero to 10 h.Incretin hormones [glucagon like peptide-1(GLP-1),peptide tyrosine-tyrosine(PYY) and glucose dependent insulinotropic polypeptide(GIP)] were then quantitated.The impact of pharmacological inhibition of DGAT1 on the incretin effect was evaluated in WT mice.Additionally,a comparison of loss of DGAT1 function either by genetic ablation or pharmacological inhibition.To further elucidate the pathways and mechanisms involved in the incretin response to DGAT1 inhibition,other interventions [inhibitors of dipeptidyl peptidase-IV(sitagliptin),pancreatic lipase(Orlistat),GPR119 knockout mice] were evaluated.RESULTS DGAT1 deficient mice and wildtype C57/BL6J mice werelipid challenged and levels of both active and total GLP-1 in the plasma were increased.This response was further augmented with DGAT1 inhibitor PF-04620110 treated wildtype mice.Furthermore,PF-04620110 was able to dose responsively increase GLP-1 and PYY,but blunt GIP at all doses of PF-04620110 during lipid challenge.Combination treatment of PF-04620110 and Sitagliptin in wildtype mice during a lipid challenge synergistically enhanced postprandial levels of active GLP-1.In contrast,in a combination study with Orlistat,the ability of PF-04620110 to elicit an enhanced incretin response was abrogated.To further explore this observation,GPR119 knockout mice were evaluated.In response to a lipid challenge,GPR119 knockout mice exhibited no increase in active or total GLP-1 and PYY.However,PF-04620110 was able to increase total GLP-1 and PYY in GPR119 knockout mice as compared to vehicle treated wildtype mice.CONCLUSION Collectively,these data provide some insight into the mechanism by which inhibition of DGAT1 enhances intestinal hormone release. | Benjamin S Maciejewski Tara B Manion Claire M Steppan | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，4： | 2 |
| 4 | ABO incompatibility in renal transplantation显示文摘ABO blood group incompatibility(ABO-I)was historically considered an absolute contraindication to kidney transplantation due to the significant risk of acute antibody-mediated rejection and early graft loss.Nevertheless,the urge to minimize the gap between the candidates’number on the waitlist for kidney transplants and the available kidney donors encourage investigation into finding ways to use organs from ABO-I kidney donors,especially in the era of using more potent immunosuppression therapies.This review aims to discuss a general overview of ABO-I kidney transplantation and the different protocols adopted by some transplant centers to meaningfully overcome this barrier. | Mahmoud Mohamed Tara Sweeney Duaa Alkhader Mahmoud Nassar Ahmed Alqassieh Sofia Lakhdar Nso Nso Tibor Fulop Ahmed Daoud Karim M Soliman | 2021 | World Journal of Transplantation2021，11，9： | 2 |
| 5 | Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 201 1 - February 2012显示文摘 | McIntyre Mary G Stevens Kelly M Davidson Sherri Pippin Tina Magill Dagny Kulhanjian Julie A Kelly Daniel Greenhow Tara L Salas Maria L Yagi Shigeo Padilla Tasha Berumen Ricardo Glaser Carol Landry Marie Louise Lott Jason Chen Lei Paulson | 2012 | EN2012，，12： | 2 |
| 6 | Effects of the Medicago scutellata trypsin inhibitor (MsTI) on cisplatin-induced cytotoxicity in human breast and cervical cancer cells显示文摘 | Lanza A Tara A Catalano M | 2004 | Anticancer Res2004，24，1： | 1 |
| 7 | Implanted fiberoblasts genetically engineered to produce BDNF prevent MPTP toxicity to dopaminergic neurons in the rat显示文摘 | David M Tara A Wendy R | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 8 | Prooxidant-antioxidant balance in pregnancy:a randomized double-blind placebo-controlled trial of selenium supplementation显示文摘 | Tara F Rayman M P Boskabadi H | 2010 | Perinat Med2010，38，5： | 1 |
| 9 | Integrated Hydrologic Mod- eling with Geographic Information Systems 显示文摘 | Ross M A Tara O D | 1993 | Journal of Water Resources Planning and Manage- ment1993，119，2： | 1 |
| 10 | The use of tutor feedback and student self-assessment in summative assessment tasks: Towards transparency for students and for tutors 显示文摘 | Taras M | 2001 | Assessment and Evaluation in Higher Education2001，26，6： | 1 |
| 11 | Performance,diarrhea inci-dence,and occurrence of Escherichia coli virulence genes during long-term administration of aprobiotic Enterococcus faecium strain to sows andpiglets显示文摘 | TARAS D VAHJEN W MACHA M | 2006 | American Society of Animal Science2006，84，： | 1 |
| 12 | Performance, diarrheaincidence, and occurrence of Escherichia coli virulencegenes during long-term administration of a probioticEnterococcus faecium strain to sows and piglets显示文摘 | Taras D Vahjen W Macha M | 2006 | Journalof Animal Science2006，84，3： | 1 |
| 13 | A couple - based intervention for patients and caregivers facing end - stage cancer:Outcomes of a randomized controlled trial显示文摘 | Linda M McLeanl Tara Walton Gary Rodin | 2013 | Psycho- Oncology2013，22，1： | 1 |
| 14 | Six sigma culture as a management principle 显示文摘 | Tara R M Jones G D | 2011 | Transfusion2011，51，7： | 1 |
| 15 | Modifications of the Helbing-Molnar-Farkas-Vicsek Social Force Model for Pedestrian Evolution显示文摘 | Taras I Lakoba D J Kaup Neal M Finkelstein | 2005 | Simultion2005，81，5： | 1 |
| 16 | Assessment - Summative and Formative - Some Theoretical Reflections 显示文摘 | Taras M | 2005 | British Journal of Educational Studies2005，53，4： | 1 |
| 17 | Edible packaging显示文摘 | TARA H HUGH M C | 2001 | Academic Research Library2001，8，11： | 1 |
| 18 | Comparison of moisture content distribution, stress distribution and shrinkage of red oak lumber dried by a radio-frequency/vacuum drying process and a conventional kiln 显示文摘 | Harris R A Taras M A | 1984 | Forest Products Journal1984，34，1： | 1 |
| 19 | Conceptual frameworks for SIA revised:a cumulative effects study on lead contamination and economic change显示文摘 | HELEN R TARA K M | 2006 | Impact Assessment and Project Appraisal2006，，6： | 1 |
| 20 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink David N Gomes Tara Ko Dennis T Szmitko Paul E Austin Peter C Tu Jack V Henry David A Kopp Alex Mamdani Muhammad M | 2009 | Canadian Medical Association. Journal2009，，7： | 1 |
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