|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn’s disease显示文摘AIM: To investigate the frequency of the common NOD2/CARD15 susceptibility variants and two functional polymorphisms of OCTN cation transporter genes in Hungarian pediatric patients with Crohn’s disease (CD). METHODS: A cohort of 19 unrelated pediatric and 55 unrelated adult patients with Crohn’s disease and 49 healthy controls were studied. Genotyping of the three common CD-associated CARD15 variants (Arg702Trp, Gly908Arg and 1007finsC changes) with the SLC22A4 1672C→T, and SLC22A5 -207G→C mutations was performed by direct sequencing of the specifi c regions of these genes.RESULTS: At least one CARD15 mutation was present in 52.6% of the children and in 34.5% of the adults compared to 14.3% in controls. Surprisingly, strongly different mutation profi le was detected in the pediatric versus adult patients. While the G908R and 1007finsC variants were 18.4% and 21.1% in the pediatric group, they were 1.82% and 11.8% in the adults, and were 1.02% and 3.06% in the controls, respectively. The R702W allele was increased approximately two-fold in the adult subjects, while in the pediatric group it was only approximately 64% of the controls (9.09% in the adults, 2.63% in pediatric patients, and 4.08% in the controls). No accumulation of the OCTN variants was observed in any patient group versus the controls.CONCLUSION: The frequency of the NOD2/CARD15 susceptibility variants in the Hungarian pediatric CD population is high and the profile differs from the adult CD patients, whereas the results for SLC22A4 and SLC22A5 mutation screening do not confirm the assumption that the carriage of these genotypes means an obligatory susceptibility to CD. | Judit Bene Lili Magyari Gábor Talián Katalin Komlósi Beáta Gasztonyi Beáta Tari gnes Várkonyi Gyula Mózsik Béla Melegh | 2006 | World Journal of Gastroenterology2006，12，34： | 6 |
| 2 | Enucleation with hydroxyapatite implantation versus evisceration plus scleral quadrisection and alloplastic implantation显示文摘 | Tari AS Malihi M Kasaee A | 2009 | Ophthal Plast Reconstr Surg2009，25，2： | 1 |
| 3 | Processing of Porous C ordierite Bodies by Starch Consolidation 显示文摘 | Aires H M Tari G Fonseca A T | 1998 | Materials Research Bulletin1998，33，10： | 1 |
| 4 | HER2/neu increases the expression of Wilms'tumor 1 (WT-1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cell显示文摘 | Tuna M Chavez-Reyes A Tari AM | 2005 | Oncogene2005，24，9： | 1 |
| 5 | Influence of the Stabilizing Mechanism and Solid Loading on Slip Casting of Alumina 显示文摘 | Tari G Ferreira J M Lyckfeldt O | 1998 | Europ Ceram SOc1998，18，： | 1 |
| 6 | KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2显示文摘 | Zang X P Siwak D R Nguyen T X Tari A M Pento J T | 2004 | Clin Exp Metastasis2004，21，： | 1 |
| 7 | Study of silicone coating adhesion to an epoxy undercoat using silane compounds Effect of silane type and application method显示文摘 | Esfandeh M Mirabedini S M Pazokifard S Tari M | 2007 | Colloids and Surfaces A:Physicochem Eng Aspects2007，302，1： | 1 |
| 8 | Stroke prediction after transient ischemic attacks in patients admitted to a stroke unit 显示文摘 | TARI CAPONE F CAVALLARI M CASOLLA B | 2012 | Eur Neurol2012，67，1： | 1 |
| 9 | Liposomal Bcl-2 antisense oligonueleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins显示文摘 | Konopleva M Tari AM Estrov Z | 2000 | Blood2000，95，12： | 1 |
| 10 | Liposomal Bcl-2 antisense oligonucleotides enhance proliferation,sensitize acute myeloid leukemia to cytosine-arabinoside,and induce apoptosis independent of other antiapoptotic proteins显示文摘 | KONOPLEVA M TARI AM ESTROV Z | 2000 | Blood2000，95，12： | 1 |
| 11 | Liposomal bcl-2 antisense oligonucleotides enhance proliferation,sensitize acute myeloid leukemia to cytosine2arabinoside and induce apoptosis independent of other antiapoptotic proteins显示文摘 | Konopleva M Tari AM Estrov Z | 2000 | Blood2000，95，： | 1 |
| 12 | Synergy of polysaccharide mixtures in gelcasting of alumina 显示文摘 | Olhero S M Tari G Coimbra M A | 2000 | J Europ Ceram Soc2000，20，： | 1 |
| 13 | The human immune system in hu - PBL - SCID mice 显示文摘 | Tary - Lehmann M Saxon A Lehmann PV | 1995 | Immunol Today1995，16，11： | 1 |
| 14 | Influence of particle size distribution on colloidal processing of alumina显示文摘 | TARI G FERREIRA J M FONSECA A T | 1998 | J Eur Ceram Soc1998，18，： | 1 |
| 15 | High efficacy of bis- muth subcitrate for Helicobacter pylori eradication in pangas- tritis显示文摘 | Severi C Abdullahi M Tari R | 2009 | Dig Liver Dis2009，41，： | 1 |
| 16 | Ethnic and gender differences in applicants' decision-making processes:An application of the theory of reasoned action显示文摘 | Van Hooft E A J Born M P Taris T W Van der Flier H | | 0，，02： | 1 |
| 17 | Job search and the theory of planned behavior: Minority majority group differences in The Netherlands 显示文摘 | Van Hooft J Born M Taris T W | 2004 | Journal of Vocational Behavior2004，65，2： | 1 |
| 18 | Rabeprazole :quest for the best PPI 显示文摘 | Tari A Kawano M Kodama K | 2002 | J Gastroenterol2002，37，： | 1 |
| 19 | Perceived fairness in personnel selection:Determinants and outcomes in different stages of the assessment procedure显示文摘 | Van Vianen A E M Taris R Scholten E Schinkel S | | 0，，1： | 1 |
| 20 | Failure analysis of ethylene cracking tube 显示文摘 | Tari V Najafizadeh A Aghaei M | 2009 | Journal of Failure Analysis and Prevention2009，9，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员