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| 1 | Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)显示文摘There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE combined with PD-(L)1 inhibitors and MTT in real-world situations.In this nationwide,retrospective,cohort study,826 HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(combination group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2018 to May 2021.The primary endpoint was progression-free survival(PFS)according to modified RECIST.The secondary outcomes included overall survival(OS),objective response rate(ORR),and safety.We performed propensity score matching approaches to reduce bias between two groups.After matching,228 pairs were included with a predominantly advanced disease population.Median PFS in combination group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002).OS and ORR were also significantly higher in combination group(median OS,19.2[16.1-27.3]vs.15.7 months[13.0-20.2];adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;P<0.001).Grade 3/4 adverse events were observed at a rate of 15.8%and 7.5%in combination and monotherapy groups,respectively.Our results suggest that TACE plus PD-(L)1 blockades and MTT could significantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile. | Hai-Dong Zhu Hai-Liang Li Ming-Sheng Huang Wei-Zhu Yang Guo-Wen Yin Bin-Yan Zhong Jun-Hui Sun Zhi-Cheng Jin Jian-Jian Chen Nai-Jian Ge Wen-Bin Ding Wen-Hui Li Jin-Hua Huang Wei Mu Shan-Zhi Gu Jia-Ping Li Hui Zhao Shu-Wei Wen Yan-Ming Lei Yu-Sheng Song Chun-Wang Yuan Wei-Dong Wang Ming Huang Wei Zhao Jian-Bing Wu Song Wang Xu Zhu Jian-Jun Han Wei-Xin Ren Zai-Ming Lu Wen-Ge Xing Yong Fan Hai-Lan Lin Zi-Shu Zhang Guo-Hui Xu Wen-Hao Hu Qiang Tu Hong-Ying Su Chuan-Sheng Zheng Yong Chen Xu-Ya Zhao Zhu-Ting Fang Qi Wang Jin-Wei Zhao Ai-Bing Xu Jian Xu Qing-Hua Wu Huan-Zhang Niu Jian Wang Feng Dai Dui-Ping Feng Qing-Dong Li Rong-Shu Shi Jia-Rui Li Guang Yang Hai-Bin Shi Jian-Song Ji Yu-E Liu Zheng Cai Po Yang Yang Zhao Xiao-Li Zhu Li-Gong Lu Gao-Jun Teng | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 7 |
| 2 | Strain hardening behavior of Mg-Y alloys after extrusion process显示文摘The strain hardening is an effective mode of enhancing mechanical properties in alloys.In this work,the strain hardening behaviors of Mg-xY(x=1,2,and 3 wt%)after extrusion process was investigated using uniaxial tensile tests.Results suggest that the Mg-xY alloys are composed ofα-Mg with a little amount of Mg24Y5 phase.The average grain size reduces from 19.8μm to 12.2μm as the Y content adds from 1 wt%to 2 wt%.Nevertheless,when Y content reaches 3 wt%,the grain size reaches to 12.9μm,which is close to that of Mg-2Y.The strain hardening rate decreases from 883 MPa to 798 MPa at(σ-σ0.2)=40 MPa,and Mg-2Y and Mg-3Y have the similar strain hardening response.Moreover,Mg-1Y shows an obvious ascending stage after the steep decreasing stage,which is mainly caused by the activation of twinning.The strain hardening behavior of Mg-xY is explained based on understanding the roles of the deformation mechanisms via deformation microstructure analysis and Visco-Plastic Self Consistent(VPSC)model.The variation of strain hardening characteristics with increasing Y content is related to the effects of grain size and texture. | Chaoyue Zhao Ziyan Li Jiahui Shi Xianhua Chen Teng Tu Zhu Luo Renju Cheng Andrej Atrens Fusheng Pan | 2019 | Journal of Magnesium and Alloys2019，7，4： | 6 |
| 3 | Dissipation of polycyclic aromatic hydrocarbons and microbial activity in a field soil planted with perennial ryegrass显示文摘 | Dengqiang FU Ying TENG Yuanyuan SHEN Mingming SUN Chen TU Yongming LUO Zhengao LI Peter CHRISTIE | 2012 | Frontiers of Environmental Science & Engineering2012，6，3： | 6 |
| 4 | Strain hardening of as-extruded Mg-xZn(x=1, 2, 3 and 4 wt%) alloys显示文摘The influence of Zn on the strain hardening of as-extruded Mg-x Zn(x = 1, 2, 3 and 4 wt%) magnesium alloys was investigated using uniaxial tensile tests at 10^(-3)s^(-1) at room temperature. The strain hardening rate,the strain hardening exponent and the hardening capacity were obtained from true plastic stress-strain curves. There were almost no second phases in the as-extruded Mg-Zn magnesium alloys. Average grain sizes of the four as-extruded alloys were about 17.8 μm. With increasing Zn content from 1 to 4 wt%, the strain hardening rate increased from 2850 MPa to 6810 MPa at(б-б_(0.2)) = 60 MPa, the strain hardening exponent n increased from 0.160 to 0.203, and the hardening capacity, Hc increased from 1.17 to 2.34.The difference in strain hardening response of these Mg-Zn alloys might be mainly caused by weaker basal texture and more solute atoms in the α-Mg matrix with higher Zn content. | Chaoyue Zhao Xianhua Chen Fusheng Pan Jingfeng Wang Shangyu Gao Teng Tu Chunquan Liu Jiahao Yao Andrej Atrens | 2019 | Journal of Materials Science & Technology2019，35，1： | 4 |
| 5 | Atmospheric fine particles in a typical coastal port of Yangtze River Delta显示文摘In recent decades, coastal ports have experienced rapid development and become an important economic and ecological hub in China. Atmospheric particle is a research hotspot in atmospheric environmental sciences in inland regions. However, few studies on the atmospheric particle were conducted in coastal port areas in China, which indeed suffers atmospheric particle pollution. Lack of the physicochemical characteristics of fine particles serves as an obstacle toward the accurate control for air pollution in the coastal port area in China. Here, a field observation was conducted in an important coastal port city in Yangtze River Delta from March 6 to March 19, 2019. The average PM2.5 concentration was 63.7 ±27.8 μg/m^3 and NO3^-, SO4^2-, NH4^+, and organic matter accounted for ?60% of PM 2.5. Fe was the most abundant trace metal element and V as the ship emission indicator was detected. Transmission electron microscopy images showed that SK-rich, soot, Fe, SK-soot and SK-Fe were the major individual particles in the coastal port. V and soluble Fe were detected in sulfate coating of SK-Fe particles. We found that anthropogenic emissions, marine sea salt, and secondary atmosphere process were the major sources of fine particles. Backward trajectory analysis indicated that the dominant air masses were marine air mass, inland air mass from northern Zhejiang and inland-marine mixed air mass from Shandong and Shanghai during the sampling period. The findings can help us better understand the physicochemical properties of atmospheric fine particles in the coastal port of Eastern China. | Qi Yuan Xiaomi Teng Shaoxuan Tu Binxin Feng Zhiyu Wu Hang Xiao Qiuliang Cai Yinxiao Zhang Qiuhan Lin Zhaoce Liu Mengmeng He Xiaokun Ding Weijun Li | 2020 | Journal of Environmental Sciences2020，32，12： | 4 |
| 6 | The effect of capping with natural and modified zeolites on the release of phosphorus and organic contaminants from river sediment显示文摘A microcosm system that included river sediment,water and different zeolite capping materials(natural zeolite,surfactant-modified zeolite(SMZ),or aluminum modified zeolite(AMZ))was designed to study the effect of capping on the release of phosphorus and three organic pollutants(phenol,pyridine,and pyrene)from the sediment to the overlying water over the course of three month.For the same amount of the three capping materials,the efficiency of phosphorus inactivation was in the order of SMZ>AMZ>natural zeolite.The inactivation of phosphorus was mainly caused by the covering effect,co-precipitation and adsorption by the capping materials.The different zeolites gave different results for the release of phenol,pyridine,and pyrene from the sediment.When natural zeolite was used as the capping material,there was no effect on the release of pyrene and pyridine,whereas capping the sediment with SMZ or AMZ inhibited the release of pyrene and pyridine but to different extents.However,for controlling the release of phenol from the sediment,aluminum modified zeolite was the most efficient material,whereas no effects were observed when natural zeolite or SMZ were used.The different capabilities of the zeolite materials for controlling the release of different organic pollutants are related to the differences in the electrical properties of these pollutants. | Shujuan SUN Lei WANG Suiliang HUANG Teng TU Hongwen SUN | 2011 | Frontiers of Chemical Science and Engineering2011，5，3： | 3 |
| 7 | A High-Ductility Mg–Zn–Ca Magnesium Alloy显示文摘A new kind of Mg–2 Zn–0.6 Ca(wt%) alloy was fabricated by casting and hot extrusion as a high-ductility structural material. The extruded alloy exhibits a superior elongation of ~30%, yield strength of 130 MPa and ultimate tensile strength of 280 MPa along the extrusion direction at room temperature. Microstructure, texture and tensile properties of the extruded alloy were investigated in details. The remarkable improvement of ductility is ascribed to the weakened basal texture, refined grains and a small number of second phase in the alloy. | Teng Tu Xian-Hua Chen Jiao Chen Chao-Yue Zhao Fu-Sheng Pan | 2019 | Acta Metallurgica Sinica(English Letters)2019，32，1： | 2 |
| 8 | The giant magnetocaloric effect in Gd_(5)Si_(2)Ge_(2)with low purity gadolinium显示文摘The giant magnetocaloric effect Gd5Si2Ge2 alloy was prepared with 99wt% low purity commercial Gd. Pow-der XRD and magnetic measurements showed that the Gd5Si2Ge2 alloy annealed at 1200℃ for 1 h had a significant magnetic- crystallographic first order phase transition at about 270 K. The maximal magnetic entropy change is 17.55 J·kg?1·K?1 under a magnetic field change of 0―5 T. The distinct increase of magnetic entropy change belongs to the first-order phase transition from the orthorhombic Gd5Si4-type to the monoclinic Gd5Si2Ge2-type after high temperature heat-treatment. | ZHANG Tiebang CHEN Yungui FU Hao TENG Baohua TANG Yongbai TU Mingjing | 2005 | Chinese Science Bulletin2005，50，16： | 2 |
| 9 | Experimental Research on the Prevention and Treatment of Shufeng Xuanfei Prescriptions on the Rat Chronic Serous Glomerulonephritis显示文摘 | TENG Yu ZHANG Qiu-ju JIANG Yan TU Heng-jing | 2012 | 世界最新医学信息文摘2012，12，2： | 2 |
| 10 | Reduction of NO with NH3 over carbon catalysts-the influence of carbon surfaces structure and the global kinetics显示文摘 | Teng H Hsu Y F Tu Y T | 1999 | Applied Catalysis B: Environmental1999，20，2： | 2 |
| 11 | The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif显示文摘 | Tu S Teng YC Yuan C | 2008 | Nat Struct Mol Biol2008，15，4： | 1 |
| 12 | Reduction of NO with NH3 over carbon catalysts-the influence of carbon surface structures and the global kinetics显示文摘 | Teng H Hsu Y F Tu Y T | 1999 | Applied Catalysis B: Environmental1999，20，2： | 1 |
| 13 | Reduction of NO with NH3 over carbon catalysts-the influence of carbon surface and the global kinetics显示文摘 | TENG H H HSU Y F TU Y T | 1999 | Appl Catal B:Environ1999，20，2： | 1 |
| 14 | Reaction of NO with NH3 over carbon catalysts,The effects of treating carbon with H2SO4 and HNO3显示文摘 | Teng Hsisheng Tu Yingtsung Lai Yuchung | 2001 | Carbon2001，39，： | 1 |
| 15 | Re- duction of NO with NH3 over Carbon Catalysts:the Effects of Treating Carbon with H2SO4 and HNO3显示文摘 | Hsisheng Teng Ying-Tsung Tu Yu-Chung Lai | | 0，，04： | 1 |
| 16 | Reduction of NO with NH3 over Carbon Catalysts:the Influence of Carbon Surface Structures and the Global Kinetics显示文摘 | Hsisheng Teng Yung-Fu Hsu Ying-Tsung Tu | | 0，，： | 1 |
| 17 | Reduction of NO with NH3 over carbon catalysts-the influence of carbon surface structures and the global kinetics显示文摘 | TENG H HSU Y-F TU Y-T | 1999 | Appl Catal B1999，20，2： | 1 |
| 18 | Collusion Potential Assessment in Electricity Markets Considering Generation Flexibility显示文摘The collusion among various generating units has been a problematic issue affecting the fairness and transparency of electricity markets.Therefore,it is of great significance to assess the potential of such collusion in the electricity market.However,the previous assessment studies primarily focused on the bidding behaviors of collusive generating units,without considering the influences of generation flexibility,such as ramp rates.In this paper,a novel assessment method is proposed to evaluate the collusion potential in the electricity market considering generation flexibility.First,a bi-level optimization model is developed to simulate the collusive strategies of dif-ferent generating units,including the withholding of generation capacities and ramp rates,as well as the uplifting of minimum outputs and bidding prices.In the upper-level problem,collusive generating units optimize their offering strategies to optimize the generation profits without violating the regulatory laws.The lower-level problem is a day-ahead economic dispatch model which minimizes the dispatching costs.Based on the optimal collusive strategies determined by the bi-level model,a framework is then proposed to assess the collusion potential in electricity markets.Moreover,price-based and profit-based indices are proposed to quantitatively evaluate the collusion potential of different generating units.Finally,the proposed assessment method is validated on a modified IEEE 39-node system.The numerical results demonstrated that generation flexibility can be exploited collusively for making excessive profits,particularly during load peaks and valleys.Index Terms-Collusionpotential,economic cdispatch,generation flexibility,ramp rates,strategic withholding. | Teng Tu Yi Ding Peng Ji Minglei Bao Nan Shang Yonghua Song Dan Zeng | 2023 | CSEE Journal of Power and Energy Systems2023，9，4： | 1 |
| 19 | The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif显示文摘 | Tu S Teng YC Yuan C | | 0，，04： | 1 |
| 20 | Influence of arbuscular mycorrhiza andrhizobium on phytoremediation by alfalfa of an agriculturalsoil contaminated with weathered PCBs: A field study 显示文摘 | Teng Y Luo YM Sun XH Tu C Xu L Liu WX Li ZG Christie P | 2010 | International Journal of Phytoremediation2010，12，： | 1 |
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