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| 1 | Regional applicability of seven meteorological drought indices in China显示文摘The definition of a drought index is the foundation of drought research.However,because of the complexity of drought,there is no a unified drought index appropriate for different drought types and objects at the same time.Therefore,it is crucial to determine the regional applicability of various drought indices.Using terrestrial water storage obtained from the Gravity Recovery And Climate Experiment,and the observed soil moisture and streamflow in China,we evaluated the regional applicability of seven meteorological drought indices:the Palmer Drought Severity Index(PDSI),modified PDSI(PDSI_CN) based on observations in China,self-calibrating PDSI(scPDSI),Surface Wetness Index(SWI),Standardized Precipitation Index(SPI),Standardized Precipitation Evapotranspiration Index(SPEI),and soil moisture simulations conducted using the community land model driven by observed atmospheric forcing(CLM3.5/ObsFC).The results showed that the scPDSI is most appropriate for China.However,it should be noted that the scPDSI reduces the value range slightly compared with the PDSI and PDSI_CN;thus,the classification of dry and wet conditions should be adjusted accordingly.Some problems might exist when using the PDSI and PDSI_CN in humid and arid areas because of the unsuitability of empiricalparameters.The SPI and SPEI are more appropriate for humid areas than arid and semiarid areas.This is because contributions of temperature variation to drought are neglected in the SPI,but overestimated in the SPEI,when potential evapotranspiration is estimated by the Thornthwaite method in these areas.Consequently,the SPI and SPEI tend to induce wetter and drier results,respectively.The CLM3.5/ObsFC is suitable for China before 2000,but not for arid and semiarid areas after 2000.Consistent with other drought indices,the SWI shows similar interannual and decadal change characteristics in detecting annual dry/wet variations.Although the long-term trends of drought areas in China detected by these seven drought indices during 1961-2013 are consistent,obvious differences exist among the values of drought areas,which might be attributable to the definitions of the drought indices in addition to climatic change. | YANG Qing LI MingXing ZHENG ZiYan MA ZhuGuo | 2017 | Science China Earth Sciences2017，60，4： | 21 |
| 2 | The basic characteristics and spatial patterns of global cultivated land change since the 1980s显示文摘在这份报纸,我们用全球基于向量的陆地使用 / 登陆盖子数据分析了在 1982 和 2011 之间的栽培陆地变化的空间模式。(1 ) 我们的分析证明全部的全球栽培陆地区域增加了 528.768 吗?? | YAO Ziyan ZHANG Lijuan TANG Shihao LI Xiaxiang HAO Tiantian | 2017 | Journal of Geographical Sciences2017，27，7： | 17 |
| 3 | Strain hardening behavior of Mg-Y alloys after extrusion process显示文摘The strain hardening is an effective mode of enhancing mechanical properties in alloys.In this work,the strain hardening behaviors of Mg-xY(x=1,2,and 3 wt%)after extrusion process was investigated using uniaxial tensile tests.Results suggest that the Mg-xY alloys are composed ofα-Mg with a little amount of Mg24Y5 phase.The average grain size reduces from 19.8μm to 12.2μm as the Y content adds from 1 wt%to 2 wt%.Nevertheless,when Y content reaches 3 wt%,the grain size reaches to 12.9μm,which is close to that of Mg-2Y.The strain hardening rate decreases from 883 MPa to 798 MPa at(σ-σ0.2)=40 MPa,and Mg-2Y and Mg-3Y have the similar strain hardening response.Moreover,Mg-1Y shows an obvious ascending stage after the steep decreasing stage,which is mainly caused by the activation of twinning.The strain hardening behavior of Mg-xY is explained based on understanding the roles of the deformation mechanisms via deformation microstructure analysis and Visco-Plastic Self Consistent(VPSC)model.The variation of strain hardening characteristics with increasing Y content is related to the effects of grain size and texture. | Chaoyue Zhao Ziyan Li Jiahui Shi Xianhua Chen Teng Tu Zhu Luo Renju Cheng Andrej Atrens Fusheng Pan | 2019 | Journal of Magnesium and Alloys2019，7，4： | 6 |
| 4 | Biodegradation of indole by a newly isolated Cupriavidus sp. SHE显示文摘Indole, a typical nitrogen heterocyclic aromatic pollutant, is extensively spread in industrial wastewater. Microbial degradation has been proven to be a feasible approach to remove indole, whereas the microbial resources are fairly limited. A bacterial strain designated as SHE was isolated and found to be an efficient indole degrader. It was identified as Cupriavidus sp. according to 16 SrRNA gene analysis. Strain SHE could utilize indole as the sole carbon source and almost completely degrade 100 mg/L of indole within 24 hr. It still harbored relatively high indole degradation capacity within p H 4–9 and temperature 25°C–35°C. Experiments also showed that some heavy metals such as Mn2+, Pb2+and Co2+did not pose severe inhibition on indole degradation. Based on high performance liquid chromatography–mass spectrum analysis, isatin was identified as a minor intermediate during the process of indole biodegradation. A major yellow product with m/z 265.0605(C15H8N2O3) was generated and accumulated, suggesting a novel indole conversion pathway existed. Genome analysis of strain SHE indicated that there existed a rich set of oxidoreductases, which might be the key reason for the efficient degradation of indole. The robust degradation ability of strain SHE makes it a promising candidate for the treatment of indole containing wastewater. | Yuanyuan Qu E.Shen Qiao Ma Zhaojing Zhang Ziyan Liu Wenli Shen Jingwei Wang Duanxing Li Huijie Li Jiti Zhou | 2015 | Journal of Environmental Sciences2015，27，8： | 5 |
| 5 | Endothelial cells-targeted soluble human Delta-like 4 suppresses both physiological and pathological ocular angiogenesis显示文摘Due to its essential roles in angiogenesis, Notch pathway has emerged as an attractive target for the treatment of pathologic angiogenesis. Although both activation and blockage of Notch signal can impede angiogenesis, activation of Notch signal may be more promising because it was shown that long-term Notch signal blockage resulted in vessel neoplasm. However, an in vivo deliverable Notch ligand with highly efficient Notch-activating capacity has not been developed. Among all the Notch ligands, Delta-like4(Dll4) is specifically involved in angiogenesis. In this study, we generated a novel soluble Notch ligand h D4 R, which consists of the Delta-Serrate-Lag-2 fragment of human Dll4 and an arginine-glycine-aspartate(RGD) motif targeting endothelial cells(ECs). We demonstrated that h D4 R could bind to ECs through its RGD motif and effectively triggered Notch signaling in ECs. Further, we confirmed that h D4 R could suppress angiogenesis in vitro as manifested by network formation assay and sprouting assay. More importantly, h D4 R efficiently repressed neonatal retinal angiogenesis and laser-induced choroidal neovascularization(CNV) as well in vivo. In conclusion, we have developed an in vivo deliverable Notch ligand h D4 R, which suppresses angiogenesis both in vitro and in vivo, thus providing a new approach to tackle excessive angiogenesis relevant disease such as CNV. | YAN XianChun YANG ZiYan CHEN Yan LI Na WANG Li DOU GuoRui LIU Yuan DUAN JuanLi FENG Lei DENG SanMing HAN Hua ZHANG Ping | 2015 | Science China(Life Sciences)2015，58，5： | 5 |
| 6 | Suppress voltage decay of lithium-rich materials by coating layers with different crystalline states显示文摘Li-rich oxides are considered as the most commercial potential cathode materials due to the high theoretical specific discharge capacity. Here, ZrO_(2) in different crystalline states are applied as the coating layers to enhance the electrochemical performance of hollow Li[Li_(0.2)Mn_(0.54)Ni_(0.13)Co_(0.13)]O_(2) materials.Meanwhile, a series of characterizations(XRD, SEM, TEM, EDX etc.) are conducted to compare the effects of ZrO_(2) coating layer with different crystalline states on the host material. The results elucidate that the Li-rich Mn-based material with the polycrystal ZrO_(2) coating layer has a slight advantage in rate performance, while the host material with the single crystal ZrO_(2)-coating layer has a better cycling performance and effectively suppresses voltage decay with the effect of excellently inhibiting layered to spinel-like phase transition and metal dissolution during charging and discharging process. | Zhiwei Zhou Ziyan Luo Zhenjiang He Junchao Zheng Yunjiao Li Cheng Yan Jing Mao | 2021 | Journal of Energy Chemistry2021，30，9： | 4 |
| 7 | A review on novel activation strategy on carbonaceous materials with special morphology/texture for electrochemical storage显示文摘Various novel carbonaceous materials including carbon nanotubes,nano-onions,carbon microspheres,graphene nanosheets,and carbon microfibers with unique properties,such as tunable surface area and pore size,high chemical stability,cost-effective and facile preparation,have attracted enormous interest for many applications.Also essential,the activation processes play a critical role to achieve these valuable properties.In this review,we provide a thorough analysis of the emerging nano-and microscopic carbon species with special morphology/textures and currently available types of chemical activation agents,and novel activation strategy to enhance electrochemical performance of activated carbon material in electrical energy storage devices including supercapacitor and alkaline ions batteries.A particular emphasis is set on recent advance in activated carbon materials with special morphology/textures for supercapacitors and sodium ion batteries. | Yueming Li Ziyan Pu Qimeng Sun Ning Pan | 2021 | Journal of Energy Chemistry2021，30，9： | 3 |
| 8 | 2,5-Dialkoxylphenyl-l,3,4-oxadiazoles as efficient organogelators and their self-assembling property显示文摘 | Zipei SUN Xuelin DONG Yan ZHAI Ziyan Li Yaodong HUANG | 2014 | Frontiers of Chemical Science and Engineering2014，8，2： | 2 |
| 9 | Comparative analysis of metabolite changes in two contrasting rice genotypes in response to low-nitrogen stress显示文摘Identification of metabolites responsible for tolerance to low nitrogen availability(low-N)will aid in the genetic improvement of rice yield under nitrogen deficiency.In this study,a backcross introgression line(G9)and its recurrent parent Shuhui 527(SH527),which show differential responses to low-N stress,were used to identify metabolites associated with lowN tolerance in rice.Differences in metabolite contents in the leaves of G9 and SH527 at three growth stages under low-N stress were assessed by gas chromatography–mass spectrometry.Many metabolites,including amino acids and derivatives,were highly enriched in G9 compared with SH527 under the control condition,suggesting that the two genotypes had basal metabolite differences.Low-N stress induced genotype-specific as well as growth stagedependent metabolite changes.Metabolites induced specifically in G9 that were involved in glycolysis and tricarboxylic acid metabolism were enriched at the tillering and grain filling stages,and metabolites involved in nitrogen and proline metabolism were enriched at the booting stage.Enrichment of pyroglutamate,glutamate,2-oxoglutarate,sorbose,glycerate-2-P,and phosphoenolpyruvic acid in G9 suggests that these metabolites could be involved in low-N stress tolerance.The results presented here provide valuable information for further elucidation of the molecular mechanisms of low-N tolerance in crops. | Xiuqin Zhao Wensheng Wang Ziyan Xie Yongming Gao Chunchao Wang Muhammed Mahbubur Rashid Mohammad Rafiqul Islam Binying Fu Zhikang Li | 2018 | The Crop Journal2018，6，5： | 2 |
| 10 | The Role of Frontal and Occipital Cortices in Processing Sustained Visual Attention in Young Adults with Attention-Deficit/Hyperactivity Disorder:A Functional Near-Infrared Spectroscopy Study显示文摘Dear Editor,Attention deficit/hyperactivity disorder(ADHD),characterized by age-inappropriate symptoms of inattention,hyperactivity,and impulsivity,is a highly prevalent and heritable childhood-onset neurodevelopmental disorder,with impairing symptoms that persist into adulthood in up to 65%of patients[1].Adults with persistent ADHD symptoms since childhood have been found to have neurocognitive impairments in multiple domains,especially in attention and cognitive control,which significantly contribute to an increased risk of social disability,educational and occupational failure,and other comorbid psychiatric disorders,resulting in significant economic burdens to the affected individuals, their families, andsociety [2, 3]. | Ziyan Wu Yuyang Luo Yu Gao Ying Han Kai Wu Xiaobo Li | 2020 | Neuroscience Bulletin2020，36，6： | 2 |
| 11 | Synthesis and properties of novel organogelators functionalized with 5-iodo-1,2,3-triazole and azobenzene groups显示文摘 | Ziyan Li Yaodong Huang Dongli Fan Huimin Li Shuxue Liu Luyuan Wang | 2016 | Frontiers of Chemical Science and Engineering2016，10，4： | 2 |
| 12 | Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis显示文摘Herein,we report the synthesis of a biomimic hydrogel adhesive that addresses the poor healing of surgical anastomosis.Dopamine-conjugated xanthan gum(Da-g-Xan)is fabricated using deep insights into the molecular similarity between mussels'adhesive and dopamine as well as the structural similarity between barnacle cement proteins and xanthan gum.The hydrogel mimics marine animals’adherence to wet tissue surfaces.Upon applying this adhesive to colonic anastomosis in a rat model,protective effects were shown by significantly improving the bursting pressure.Mechanistically,the architecture of Da-g-Xan hydrogel is maintained by dynamic intermolecular hydrogen bonds that allow the quick release of Da-g-Xan.The free Da-g-Xan can regulate the inflammatory status and induce type 2 macrophage polarization(M2)by specifically interacting with mannose receptors(CD206)revealed by RNA-sequencing and molecular binding assays.Consequently,an appropriate microenvironment for tissue healing is created by the secretion of chemokines and growth factors from M2 macrophages,strengthening the fibroblast migration and proliferation,collagen synthesis and epithelial vascularization.Overall,this study demonstrates an unprecedented strategy for generating an adhesive by synergistic mimicry inspired by two marine animals,and the results show that the Da-g-Xan adhesive augments native tissue regenerative responses,thus enabling enhanced recovery following surgical anastomosis. | Jinjian Huang Yungang Jiang Ye Liu Yanhan Ren Ziyan Xu Zongan Li Yun Zhao Xiuwen Wu Jianan Ren | 2021 | Bioactive Materials2021，6，3： | 2 |
| 13 | Lagrangian duality and saddle points for sparse linear programming显示文摘The sparse linear programming(SLP) is a linear programming problem equipped with a sparsity constraint, which is nonconvex, discontinuous and generally NP-hard due to the combinatorial property involved.In this paper, by rewriting the sparsity constraint into a disjunctive form, we present an explicit formula of the Lagrangian dual problem for the SLP, in terms of an unconstrained piecewise-linear convex programming problem which admits a strong duality under bi-dual sparsity consistency. Furthermore, we show a saddle point theorem based on the strong duality and analyze two classes of stationary points for the saddle point problem. At last,we extend these results to SLP with the lower bound zero replaced by a certain negative constant. | Chen Zhao Ziyan Luo Weiyue Li Houduo Qi Naihua Xiu | 2019 | Science China Mathematics2019，62，10： | 1 |
| 14 | Silver-catalyzed decarboxylative C-H functionalization of cyclic aldimines with aliphatic carboxylic acids显示文摘Silver-catalyzed decarboxylative C–H alkylation of cyclic aldimines with abundant aliphatic carboxylic acids has been realized under mild reaction conditions generating the corresponding products in moderate to good yields(32%–91%).In addition,a gram-scale reaction,late-stage modification of drug,synthetic transformation of the product,and further application of the catalytic strategy were also performed.Preliminary studies indicate that the reaction undergoes a radical process. | Jingjing Wang Xue Liu Ziyan Wu Feng Li Tingting Qin Siyuan Zhang Weiguang Kong Lantao Liu | 2021 | Chinese Chemical Letters2021，32，9： | 1 |
| 15 | Bio-template route for facile fabrication of Cd (OH) 2 @ yeast hybrid microspheres and their subsequent conversion to meso- porous CdO hollow microspheres 显示文摘 | Bai B% Guan Weisheng Li Ziyan | 2011 | Mater Res Bull2011，46，1： | 1 |
| 16 | Whole-genome Duplication Reshaped Adaptive Evolution in A Relict Plant Species,Cyclocarya paliurus显示文摘Cyclocarya paliurus is a relict plant species that survived the last glacial period and shows a population expansion recently.Its leaves have been traditionally used to treat obesity and diabetes with the well-known active ingredient cyclocaric acid B.Here,we presented three C.paliurus genomes from two diploids with different flower morphs and one haplotype-resolved tetraploid assembly.Comparative genomic analysis revealed two rounds of recent whole-genome duplication events and identified 691 genes with dosage effects that likely contribute to adaptive evolution through enhanced photosynthesis and increased accumulation of triterpenoids.Resequencing analysis of 45 C.paliurus individuals uncovered two bottlenecks,consistent with the known events of environmental changes,and many selectively swept genes involved in critical biological functions,including plant defense and secondary metabolite biosynthesis.We also proposed the biosynthesis pathway of cyclocaric acid B based on multi-omics data and identified key genes,in particular gibberellinrelated genes,associated with the heterodichogamy in C.paliurus species.Our study sheds light on evolutionary history of C.paliurus and provides genomic resources to study the medicinal herbs. | Yinquan Qu Xulan Shang Ziyan Zeng Yanhao Yu Guoliang Bian Wenling Wang Li Liu Li Tian Shengcheng Zhang Qian Wang Dejin Xie Xuequn Chen Zhenyang Liao Yibin Wang Jian Qin Wanxia Yang Caowen Sun Xiangxiang Fu Xingtan Zhang Shengzuo Fang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，3： | 1 |
| 17 | Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition显示文摘Sphingosine-1-phosphate(S1P)is an important bioactive lipid molecule in cell membrane metabolism and binds to G proteincoupled S1P receptors(S1PRs)to regulate embryonic development,physiological homeostasis,and pathogenic processes in various organs.S1PRs are lipid-sensing receptors and are therapeutic targets for drug development,including potential treatment of COVID-19.Herein,we present five cryo-electron microscopy structures of S1PRs bound to diverse drug agonists and the heterotrimeric Gi protein.Our structural and functional assays demonstrate the different binding modes of chemically distinct agonists of S1PRs,reveal the mechanical switch that activates these receptors,and provide a framework for understanding ligand selectivity and G protein coupling. | Yuan Yuan Guowen Jia Chao Wu Wei Wang Lin Cheng Qian Li Ziyan Li Kaidong Luo Shengyong Yang Wei Yan Zhaoming Su Zhenhua Shao | 2021 | Cell Research2021，31，12： | 1 |
| 18 | Noise reduction for temperature-sensitive paint measurement contaminated by strong background radiation in a high enthalpy hypersonic tunnel显示文摘The strong background radiation in high enthalpy hypersonic shock tunnels has posed severe challenges for measurement using luminescent coatings.We proposed a solution for reducing background radiation from time-resolved temperature-sensitive paint(TSP)measurement in a hypersonic flow with Ma=6.5 and T_(0)=3525 K.The TSP was applied on an inlet ramp model,and the images were taken by a high-speed camera at 2 kHz under a modulated excitation.The strong background radiation led to a low signal-to-noise ratio and significant errors for the first half of the 130-ms test duration.Accordingly,three noise reduction methods were developed and evaluated based on temporal reconstruction,spatial reconstruction and robust principal component analysis(RPCA),respectively.The RPCA method showed the best performance that successfully recovered high-quality TSP data for a majority of test duration(t≥40 ms). | Di Peng Xu Liu Lingrui Jiao Ziyan Li Xin Wen Chaokai Yuan Guilai Han Yunfeng Liu Yingzheng Liu Zonglin Jiang | 2021 | Acta Mechanica Sinica2021，37，1： | 1 |
| 19 | Novel one step fabrica- tion of raspberry-like TiO2 @ yeast hybrid microspheres via electrostatic-interaction-driven self-assembled hetero- coagulation for environmental applications 显示文摘 | BAI Bo QUICI N LI Ziyan | 2001 | Chemical Engineering Journal2001，170，23： | 1 |
| 20 | Novel one step fabrica- tion of raspberry like TiO2 @ Yeast hybrid microspheres via e- lectrostatic-Interaction-driven self-assembled heterocoagulation for environmental applications显示文摘 | Bai Bo Natalia Quici Li Ziyan | 2011 | Chemical Engineering Jour- nal2011，170，： | 1 |
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