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| 1 | 微小RNA-1和微小RNA-29b对急性心肌梗死后不良心室重塑的诊断和预后价值显示文摘已知微小RNA(microRNAs,miRs)在急性心肌梗死(acute myocardial infarction,AMI)临床前期模型中可发挥纤维化和抗纤维化作用。为了评估miR-1,miR-21,miR-29b和miR-92a能否作为患者发生AMI后不良心室重塑(adverse ventricular remodeling,AVR)的循环生物标志物, | 刘莉 叶鹏 Grabmaier U Clauss S Gross L Klier I Franz WM Steinbeck G Wakili R Theiss HD Brenner C | 2017 | 中华高血压杂志2017，25，7： | 17 |
| 2 | Oxidative stress: the lowest common denominator of multiple diseases显示文摘Oxygen is essential to the human life and life of all aerobic organisms. The complete oxidation of nutrients for the biological energy supply is one of the most important prerequisites for the formation of higher life forms. However, cells that benefit from oxidative respiration also suffer from reactive oxygen species because they adapted to oxygen as an energy source. Healthy cells balance the formation and elimination of reactive oxygen species thereby creating and keeping reactive oxygen species-homeostasis. When the concentration of free radicals exceeds a critical level and homeostasis is disturbed, oxidative stress occurs leading to damage of multiple cellular molecules and compartments. Therefore, oxidative stress plays an important role in the physiology and pathology of various diseases. Often, the antioxidant protection system becomes pathologically unbalanced in the genesis of several diseases, leading to functional losses of the organism, as in the case of amyotrophic lateral sclerosis, or cells develop metabolic mechanisms to use this system as protection against external influences, such as in the case of glioblastoma cells. Either way, understanding the underlying deregulated mechanisms of the oxidative protection system would allow the development of novel treatment strategies for various diseases. Thus, regardless of the direction in which the reactive oxygen species-homeostasis disequilibrate, the focus should be on the oxidative protection system. | Veronika Matschke Carsten Theiss Johann Matschke | 2019 | Neural Regeneration Research2019，14，2： | 7 |
| 3 | Age-dependent impact of the SYNTAX-score on longer-term mortality after percutaneous coronary intervention in an all-comer population显示文摘在有 TAXUS 和心脏的外科(句法) 的经皮的冠的干预之间的 BackgroundThe 协同作用分数在有复杂冠的动脉疾病的病人是为风险层化和 revascularization 策略选择的一个验证工具。学习是分析它的年龄相关的预示的 value.MethodsSYNTAX 分数的这的目的在经历经皮的冠的干预(一种总线标准) 的 1331 个所有来者病人被计算:463 个病人 75 年和 868 个病人 < 75 年。兴趣的结果是在一个和二 years.ResultsA 点的所有原因死亡为死亡的年龄和句法分数的重要相互作用被观察在二年(P 相互作用 = 0.019 ) 然而并非在一个年后续(P 相互作用 = 0.594 ) 。在 multivariable 分析,句法分数独立地在两个年龄组预言了 1 年的死亡(< 75 年,危险比率(HR ) :1.43, 95% 信心间隔(CI ) :1.03-2.00, P = 0.034;并且 75 年, HR:1.37, 95% CI:1.01-1.85, P = 0.042 ) ,但是在更年轻的病人之中的仅仅二年的死亡(< 75 年, HR:1.33, 95% CI:1.01-1.76, P = 0.041;并且 75 年, HR:1.11, 95% CI:0.87-1.41, P = 0.394 ) 。句法分数 tertiles 是有用的成层在两个的 1 年的死亡,病人 < 75 年(句法分数 < 9, 3.8% ;9-20, 5.3% ;20, 10.3% ;P = 0.004 ) 并且 75 年(句法分数 < 11, 5.7% ;11-22.5, 16.1% ;22.5, 18.7% ;P = 0.003 ) ,但是仅仅在病人之中的二年的死亡 < 75 年(句法分数 < 9, 6.5% ;9-20, 7.6% ;20, 15% ;P < 0.001 ) 并且不在 75 个岁病人之中(句法分数 < 11, 19.4% ;11-22.5, 26.3% ;22.5, 27.9% ;P = 0.138 ).ConclusionsAge 在一种总线标准以后在长术语的死亡上修改句法分数的影响。在病人之中 < 75 年,句法分数独立地在一种总线标准以后在一个和二年点预言死亡的风险,当时在病人之中它的预兆的角色在一种总线标准以后被限制到第一年的 75 年。进一步的研究被需要为在老病人之中选择最适当的 revascularization 策略评估句法分数的价值。 | Madeleine Eickhoff Stefanie Schupke Alexander Khandoga Julia Fabian Moritz Baquet David Jochheim David Grundmann Manuela Thienel Axel Bauer Hans Theiss Stefan Brunner Jorg Hausleiter Steffen Massberg Julinda Mehilli | 2018 | Journal of Geriatric Cardiology2018，15，9： | 3 |
| 4 | VEGF in the nervous system: an important target for research in neurodevelopmental and regenerative medicine显示文摘Vascular endothelial growth factor(VEGF)in neurodevelopment and regeneration:VEGF is a well-known factor that promotes vascularization and angiogenesis.Besides this it participates in the pathogenesis of several diseases,such as colorectal carcinoma,lung cancer or diabetic retinopathy.Within the last decade,VEGF has been successfully integrated into the treatment of such diseases,for example as a therapy for colorectal cancer with the | Matthias Dumpich Carsten Theiss | 2015 | Neural Regeneration Research2015，10，11： | 3 |
| 5 | Plasmonic mode mixing in nanoparticle dimers with nm-separations via substrate-mediated coupling显示文摘 | Jesse Theiss Mehmet Aykol Prathamesh Pavaskar Stephen B. Cronin | 2014 | Nano Research2014，7，9： | 2 |
| 6 | Polysilicon thin film transistors fabricated on low temperature plastic substrates显示文摘 | Carey P Smith P Theiss D | 1999 | J Vac Sci Technol A1999，17，： | 1 |
| 7 | Type-Ⅲdens fracturewith distraction:an unstable injury:a report of three cases显示文摘 | Kirkpatrick JS Sheils T Theiss SM | 2004 | J Bone Joint Surg(Am)2004，86，11： | 1 |
| 8 | A review of the removal of anions and oxyanions of the halogen elements from aqueous solution by layered double hydroxides显示文摘 | Theiss FL Couperthwaite S J Ayoko G A | 2014 | Journal of Colloid and Interface Science2014，417，： | 1 |
| 9 | Elastic-plastic analysis of tubular transmission structures 显示文摘 | LEMASTER R NOPRATVARAKORN V THEISS T | 1988 | Computers and Structures1988，28，5： | 1 |
| 10 | Efficient gene transfer of CD40 ligand into primary B-CLL cells using recombinant adeno-aasociated virus (rAAV) vectors显示文摘 | Wendtner CM Kofler DM Theiss HD | 2002 | Blood2002，100，： | 1 |
| 11 | High capacity in vitro microcleus assay for assessment of chromosome damage:results with quinolone/naphthyridone antibacterials 显示文摘 | CIARAVINO V SUTO MJ THEISS JC | 1993 | Mutat Res1993，298，4： | 1 |
| 12 | Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence显示文摘 | Theiss S Ishdorj G Brenot A | 2006 | Int J Med Microbiol2006，296，6： | 1 |
| 13 | Local generation of C-reactive protein in diseased coronary artery venous bypass grafts and normal vascular tissue显示文摘 | Jabs W J Theissing E Nitschke M | 2003 | Circulation2003，108，12： | 1 |
| 14 | Transanal endosco- pic surgery of the rectum-testing a new method in animal experiments显示文摘 | Buess G Theiss R Hutterer F | 1983 | Leber Magen Darm1983，13，2： | 1 |
| 15 | Transanal endoscopicsurgery of the rectum-testing a new method in animal experi-ments显示文摘 | Buess G Theiss R Hhtterer F | 1983 | Leber Magen Darm1983，13，2： | 1 |
| 16 | Short segment fixation of thoracolumbar burst fractures显示文摘 | Scholl BM Theiss SM Kirkpatrick JS | 2006 | Orthopedics2006，29，8： | 1 |
| 17 | Growth hormone reduces the severity of fibrosis associated with chronic intestinal inflammation显示文摘 | Theiss AL Fuller CR Simmons JG | | 0，，01： | 1 |
| 18 | Local generation of C-reactive protein in diseased coronary artery venous bypass grafts and normal vascular tissue 显示文摘 | Jabs WJ Theissing E Nitschke M | 2003 | Circulation2003，108，12： | 1 |
| 19 | Mechanism of boron diffusion in silicon : an abqnitio and kinetic Monte Carlo study 显示文摘 | Sadigh B Lenodky T J Theiss S K | 1999 | Phys Rev Lett1999，83，21： | 1 |
| 20 | Growth factors in inflammatory bowel disease: the actions and interactions of growth hormone and insulin - like growth factor - 1 显示文摘 | Theiss AL Fruchtman S Lund PK | 2004 | Inflamm Bowel Dis2004，10，6： | 1 |
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