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| 1 | 利用手机加速度传感器探究竖直方向弹簧振子运动显示文摘研究开发了基于手机加速度传感器的竖直方向弹簧振子实验.使手机随着弹簧振子上下振动,利用手机加速度传感器软件得到弹簧振子做简谐振动以及阻尼振动的加速度变化图像.通过分析简谐振动加速度变化图象得出弹簧劲度系数、重力加速度;通过分析阻尼振动加速度变化图像得出弹簧振子做阻尼振动的加速度方程. | 张春斌 王妍琳 周少娜 肖化 杨友源 THO Siew-wei | 2015 | 大学物理2015，34，7： | 14 |
| 2 | 滇东南富宁地区基性侵入岩与峨眉山地幔柱存在成因关系吗?——来自1∶5万洞波幅和皈朝幅地质填图的证据显示文摘在滇东南富宁地区,出露一系列以辉绿岩为主、含少量辉长辉绿岩和辉绿玢岩的基性侵入岩。根据地球化学、同位素地球化学以及锆石U-Pb年代学等分析结果,前人将这些基性侵入岩视作峨眉山大火成岩省的组成部分,源自峨眉山地幔柱。国内外研究的共识认为,峨眉山地幔柱活动发生于263~252Ma之间,持续时间极短。在开展1∶2.5万大比例尺地质调查与填图(洞波幅和皈朝幅1∶5万地质调查手图)过程中,我们发现,这些基性侵入岩不仅侵入古生代地层,还侵入了富宁县皈朝一带的晚二叠世-中三叠世岛弧玄武安山岩(255~241Ma)以及早-中三叠世地层。这些地质事实表明,富宁地区基性侵入岩的形成时代至少晚于中三叠世Anisian期或更晚,与峨眉山地幔柱活动时代存在很大的时差,岩石类型与组合上也与峨眉山大火成岩省的有很大差异。根据我们填图过程中获得的基本地质事实分析,滇东南富宁地区的基性侵入岩是华南地块与北越地块间的古特提斯分支洋盆闭合、两个地块碰撞造山(即印支造山)后的岩浆活动产物,与峨眉山地幔柱没有成因关系。 | 江文 向忠金 夏文静 夏磊 张慧 PHAM Van Tho 闫全人 卫巍 | 2017 | 岩石学报2017，33，10： | 12 |
| 3 | PDX-1 expression and proliferation of duct epithelial cells after partial pancreatectomy in rats显示文摘BACKGROUND:The pancreas has a strong regeneration potential in mammals. Previous studies suggested that pancreas regeneration is correlated with proliferation and differentiation of pancreatic stem cells,but the field of pancreatic stem cells is still in its infancy. This study was undertaken to detect the expression of pancreas/duodenal homeobox-1(PDX-1) and proliferation of pancreatic duct epithelial cells in remnant pancreas during regeneration after partial pancreatectomy in rats,and characterize the source of pancreatic stem cells. METHODS:Partial pancreatectomy(90%) was performed on four-to five-week-old Sprague-Dawley rats,and duct epithelial cells and acinar cells were detected by immunohistochemical staining and scored using the 5-bromo-2-deoxyuridine(BrdU) labelling index at various time points. Western blotting and reverse transcriptase-polymerase chain reaction(RT-PCR) were used to assess the expression of PDX-1 protein and mRNA,respectively. RESULTS:At 24 hours after partial pancreatectomy,proliferation started in the main,large and small duct cells,and persisted in small duct cells to day 5. The experimental and control groups were significantly different(P<0.001). BrdU-positive acinar cells were greatly increased and reached a peak on day 5. PDX-1 protein was only faintly detectable in pancreatic ductal cells on day 1 after partial pancreatectomy. On days 2 and 3,a 2-3 fold increase in PDX-1 protein was observed,corresponding to the characteristic 42 kD protein in Western blotting. The operated and sham-operated groups also differedsignificantly(P<0.05). PDX-1 protein expression on days 5 and 7 after operation did not differ from that of the control group. RT-PCR revealed that PDX-1 mRNA expression did not significantly differ between the operated group and the sham-operated group at various time points. CONCLUSIONS:Pancreatic stem cells in pancreatic ductal epithelial cells are involved in the regeneration of remnant pancreas and the expression of PDX-1 in ductal cells is due to posttranscriptional regulation. | Liu, Tho Wang, Chun-You Gou, Shan-Miao Wu, He-Shui Xiong, Jiong-Xin Zhou, Jing | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，4： | 9 |
| 4 | 敦煌造山带南部红柳峡混杂带基质的沉积学、地球化学和年代学特征及其大地构造意义显示文摘敦煌造山带南部红柳峡混杂带基质的研究,为认识敦煌造山带的形成和演化提供了新的依据。本文从沉积学、地球化学和年代学等方面系统讨论了该混杂带基质的特征和形成环境。结果显示,基质的岩石类型主要包括变泥质岩(云母石英片岩)和变质砂岩,普遍发生强烈变形。局部弱变形变质的基质仍保留有原生沉积构造(如T_(ab)、T_(de)、T_(bde)组合的鲍马序列),反映原岩是一套浊积岩复理石。显微岩相学特征显示,基质碎屑组分以长石、石英和岩屑为主,长石和岩屑含量较高,分别为47%和27%,反映大量火成岩物质的加入,且碎屑颗粒的分选性和磨圆度较差,说明搬运距离较近。地球化学方面,低的化学蚀变指数(CIA=49~67),反映复理石基质物源区母岩经历的风化程度较低。高的成分变化指数(ICV>0.8)以及Zr/Sc-Th/Sc投图结果显示,沉积物再循环程度低,为近物源区的初次沉积。基质Sc、Cr、Co、Ni含量低,Eu/Eu*、La/Sc、Th/Sc、La/Co、Th/Co和Cr/Th等元素比值类似于来自长英质源区的沉积物,暗示其物源区母岩以中-酸性岩石为主。La/Sc-Ti/Zr和Th-ScZr/10投图结果显示,复理石基质形成于陆缘弧或活动大陆边缘构造背景。弱变形浅变质砂岩的碎屑模式表明,基质的物源来自'切割型弧-过渡型弧'源区。综上,红柳峡混杂带基质在碎屑组成方面,以再循环程度低、近物源堆积的'切割型弧-过渡型弧'源区长英质碎屑组分为主,在沉积构造方面,发育鲍马序列和深水块体搬运沉积(MTD)构造,表明基质形成于陆缘弧或活动大陆边缘的俯冲带海沟环境。碎屑锆石年代学显示三组年龄:2300Ma、1850Ma和423Ma,结合区域地质背景分析,初步认为物源碎屑可能来自混杂带北侧的三危山弧和东巴兔-蘑菇台弧的古生代花岗岩类以及俯冲折返的变质基性岩岩块。复理石基质的变质砂岩中获得的最年轻的岩浆碎屑锆石年龄为389Ma,说明该砂岩形成于中泥盆世之后,暗示敦煌造山带南部红柳峡地区洋盆尚未俯冲完毕,碰撞作用尚未开始。 | 石梦岩 侯泉林 吴春明 王浩 程南南 张谦 PHAM Van Tho | 2018 | 岩石学报2018，34，7： | 5 |
| 5 | JOINT ITERATIVE DECODING FOR SIMPLE-ENCODING SYSTEMATIC IRREGULAR-LDPC-BASED CODED COOPERATION IN NON-IDEAL RELAY CHANNEL显示文摘In this paper, a new kind of simple-encoding irregular systematic LDPC codes suitable for one-relay coded cooperation is designed, where the proposed joint iterative decoding is effectively performed in the destination which is in accordance with the corresponding joint Tanner graph characterizing two different component LDPC codes used by the source and relay in ideal and non-ideal relay cooperations. The theoretical analysis and simulations show that the coded cooperation scheme obviously outperforms the coded non-cooperation one under the same code rate and decoding complex. The significant performance improvement can be virtually credited to the additional mutual exchange of the extrinsic information resulted by the LDPC code employed by the source and its counterpart used by the relay in both ideal and non-ideal cooperations. | Chen Jingwen Yang Fengfan Luo Lin Tho Le-Ngoc | 2010 | Journal of Electronics(China)2010，27，3： | 3 |
| 6 | 巧用手机测量重力加速度显示文摘重力加速度的测量是高中物理教学中的一个重要实验,常用的测量方法有单摆法、自由落体法等。这些传统的实验法存在以下不足:用量角器测定摆角操作不方便且误差大;测量周期采用人工计时,受人体反应时间影响;只能记录几个数据,无法看到实验图象。数据采集器虽可以解决人工计时以及图象问题,但价格不菲。为克服以上不足,本文基于单摆法的原理,结合手机自带的传感器设计一个测量重力加速度的低成本的新方法。 | 张春斌 杨友源 肖化 周少娜 王妍琳 Siew Wei THO | 2014 | 中学物理教学参考2014，0，12： | 3 |
| 7 | Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine(5hmC)显示文摘As a dioxygenase, Ten-Eleven Translocation 2(TET2) catalyzes subsequent steps of 5-methylcytosine(5 mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation,and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized. Here we show that Tet2 plays an essential role in osteoclastogenesis. Deletion of Tet2 impairs the differentiation of osteoclast precursor cells(macrophages) and their maturation into bone-resorbing osteoclasts in vitro. Furthermore, Tet2^(-/-) mice exhibit mild osteopetrosis, accompanied by decreased number of osteoclasts in vivo. Tet2 loss in macrophages results in the altered expression of a set of genes implicated in osteoclast differentiation, such as Cebpa, Mafb, and Nfkbiz. Tet2 deletion also leads to a genome-wide alteration in the level of 5-hydroxymethylcytosine(5 hmC) and altered expression of a specific subset of macrophage genes associated with osteoclast differentiation. Furthermore, Tet2 interacts with Runx1 and negatively modulates its transcriptional activity. Our studies demonstrate a novel molecular mechanism controlling osteoclast differentiation and function by Tet2, that is, through interactions with Runx1 and the maintenance of genomic 5 hmC. Targeting Tet2 and its pathway could be a potential therapeutic strategy for the prevention and treatment of abnormal bone mass caused by the deregulation of osteoclast activities. | Yajing Chu Zhigang Zhao David Wayne Sant Ganqian Zhu Sarah M. Greenblatt Lin Liu Jinhuan Wang Zeng Cao Jeanette Cheng Tho Shi Chen Xiaochen Liu Peng Zhang Jaroslaw P. Maciejewski Stephen Nimer Gaofeng Wang Weiping Yuan Feng-Chun Yang Mingjiang Xu | 2018 | Genomics, Proteomics & Bioinformatics2018，16，3： | 2 |
| 8 | The ATM–Chk2 and ATR–Chk1 Pathways in DNA Damage Signaling and Cancer显示文摘 | Joanne Smith Lye Mun Tho Naihan Xu David A. Gillespie | 2010 | Advances in Cancer Research2010，，： | 2 |
| 9 | Accelerating BP-Based Iterative Low-Density Parity-Check Decoding by Modified Vertical and Horizontal Processes显示文摘Two modified BP algorithms related to vertical and horizontal processes are proposed to accelerate iterative low-density parity-check(LDPC) decoding over an additive white Gaussian noise(AWGN) channel,where the newly updated extrinsic information is immediately used in the current decoding round.Theoretical analysis and simulation results demonstrate that both the modified approaches provide significant performance improvements over the traditional BP algorithm with almost no additional decoding complexity.The proposed algorithm with modified horizontal process offers even better performance than another algorithm with the modified horizontal process.The two modified BP algorithms are very promising in practical communications since both can achieve an excellent trade-off between the performance and decoding complexity. | 陈婧文 仰枫帆 罗琳 THO Le-Ngoc | 2009 | Journal of Southwest Jiaotong University(English Edition)2009，17，4： | 2 |
| 10 | Systemic inflammatory response is a predictor of outcome in patients undergoing preoperative chemoradiation for locally advanced rectal cancer显示文摘 | R. Carruthers L. M. Tho J. Brown S. Kakumanu E. McCartney A. C. McDonald | 2012 | Colorectal Disease2012，，10： | 2 |
| 11 | Metamodeling development for vehicle frontal impact simulation 显示文摘 | Yang R J Wang N Tho C H | 2005 | Journal of Mechanical Design2005，127，5： | 1 |
| 12 | 显示文摘 | Tho N D Chau N Yu S C | 2006 | J Magn Magn Mater2006，304，2： | 1 |
| 13 | Design and control of warehouse order picking: A literature review显示文摘 | De Koster R Tho L Roodbergen K J | 2007 | European Journal of Operational Research2007，182，2： | 1 |
| 14 | Design and Control of Warehouse Order Picking: A Literature Review 显示文摘 | Rene de Koster Tho Le-Duc Kees Jan Roodbergen | 2007 | European Journal of Operational Research (S0377-2217)2007，182，2： | 1 |
| 15 | The ATM-Chk2 and ATR-Chk1Pathways in DNA damage signaling and cancer显示文摘 | Smith J Tho LM Xu N | 2010 | Adv Cancer Res2010，108，： | 1 |
| 16 | The chemical structure of kaki-tannin from immature fruit of thepersimmon (Diospy-ros kaki L)显示文摘 | Matsuo Tho | 1978 | Agricultural and Biological Chemistry1978，42，9： | 1 |
| 17 | Lattice Boltz-mann methods for shallow water flow applications显示文摘 | THO¨MMES G SEAI¨D M BANDA M | | 0，，07： | 1 |
| 18 | PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid- resistant Mycobacterium tuberculosis显示文摘 | Caws M Tho D Q Duy P M | 2007 | J Clin Microbiol2007，45，6： | 1 |
| 19 | Metamodeling development for vehicle frontal impact simulation 显示文摘 | Yang R J Wang N Tho C H Bobineau J P Wang B P | 2005 | Journal of Mechanical Design2005，127，： | 1 |
| 20 | Acute small bowel toxicity and preoperative chemoradiotherapy for rectal cancer: Investigating dose-volume relationships and role for inverse planning显示文摘 | Tho LM Glegg M Paterson J | 2006 | Int J Radiat Oncol Biol Phys2006，66，： | 1 |
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