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| 1 | Radial artery access site complications during cardiac procedures,clinical implications and potential solutions: The role of nitric oxide显示文摘Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery,as this is considered to be safer than the femoral approach.However,despite improvements in technology and techniques,complications can occur.The most common complication,arterial spasm,can cause intense pain and,in some cases,procedural failure.The incidence of spasm is dependent on several variables,including operator experience,artery size,and equipment used.An antispasmolytic cocktail can be applied to reduce spasm,which usually includes an exogenous nitric oxide(NO)donor(glyceryl trinitrate).NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm intervention.However,systemic administration can result in unwanted side-effects,such as hypotension.A method that adopts local delivery of NO might be advantageous.This review article describes the mechanisms involved in radial artery spasm,discusses the advantages and disadvantages of current strategies to reduce spasm,and highlight the potential of NO-loaded nanoporous materials for use in this setting. | Emma M Coghill Timothy Johnson Russell E Morris Ian L Megson Stephen J Leslie | 2020 | World Journal of Cardiology2020，12，1： | 4 |
| 2 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011，，9779： | 2 |
| 3 | Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes 显示文摘 | Qin Y Timothy E Graham N M | 2005 | Nature2005，436，： | 1 |
| 4 | Prevention and Control of Influenza with Vaccines Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010显示文摘 | Fiore Anthony E Uyeki Timothy M Broder Karen Finelli Lyn Euler Gary L Singleton James A Iskander John K Wortley Pascale M Shay David K Bresee Joseph S Cox Nancy J | 2010 | MMWR. Morbidity and Mortality Weekly Report2010，，： | 1 |
| 5 | Retinol-binding protein 4 and insulin resistance in lean,obese,and diabetic subjects显示文摘 | Timothy E Graham M D Yang Q | 2006 | N Engl J Med2006，354，： | 1 |
| 6 | Sim- ulating the Aerodynamic Performance and Wake Dynamics of a Vertical axis Wind Turbine显示文摘 | Frank Scheurich Timothy M Fletcher Richard E Brown | 2011 | Wind Energy2011，14，2： | 1 |
| 7 | Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘 | Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler | 2003 | American Journal of Ophthalmology2003，，5： | 1 |
| 8 | Microcomputer Control of Switehed Reluctanee Motor显示文摘 | Bimal K Bose Timothy J E Miller Paul M Szczesny | 1986 | IEEE Transactions on Industry Apptieation1986，22，4： | 1 |
| 9 | ABC of intensive care organ dysfunction显示文摘 | TIMOTHY W E SMITHIES M | 1999 | Br Med J1999，318，： | 1 |
| 10 | A molecular basis for cardiac arrhythmia:HERG mutations cause long QT syndrome显示文摘 | Curran M E Splawski I Timothy K W | 1995 | Cell1995，80，： | 1 |
| 11 | Potential Impact of Accelerating the Primary Dose of Rotavirus Vaccine in Infants显示文摘 | Elizabeth E Halvorson Timothy R Peters Beverly M Snively | 2012 | Vaccine2012，30，17： | 1 |
| 12 | Uniform price auction with locational price adjustments for competitive electricity markets 显示文摘 | ROBERT E RAY Z TIMOTHY M | 1999 | International Journal of Electrical Power and Energy System1999，21，2： | 1 |
| 13 | Designing and Deploying a Building-Wide Cognitive Radio Network Testbed 显示文摘 | Timothy R N Shajedul H S M DePoy E | 2010 | IEEE Communication Magazines2010，48，9： | 1 |
| 14 | Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons显示文摘 | Susan O McGuire Zao Dung Ling Jack W Lipton Caryl E Sortwell Timothy J Collier Paul M Carvey | 2001 | Experimental Neurology2001，，2： | 1 |
| 15 | Autothermal thermophilic aerobic waste treatment systems:A state-of-the-art review 显示文摘 | Timothy M LaPara James E Alleman | 1999 | Water Research1999，33，4： | 1 |
| 16 | Thermophilic aerobic biological wastewater treatment 显示文摘 | Timothy M Lapara James E Alleman | 1999 | Water Research1999，33，4： | 1 |
| 17 | Reactivity control options of space nuclear reactors显示文摘 | Timothy M S Mohamed S E | 2009 | Progress in Nuclear Energy2009，51，3： | 1 |
| 18 | High bandwidth fast steering mirror显示文摘 | Francisc M T Derek J E Timothy R H | 2005 | Proc SPIE2005，5877，： | 1 |
| 19 | Effects of landscape structure on nest predation in roadsides of a midwestern agroecosystem: A multiscale analysis显示文摘 | Timothy M B Louis B B Kathryn E F | 2000 | Landscape Ecology2000，15，： | 1 |
| 20 | Thermophilic aerobic biological wastewater treatment显示文摘 | Lapara Timothy M Alleman James E | 1999 | Wat Res1999，33，4： | 1 |
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