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| 1 | 925j Optimising post-operative Crohn’s disease management: best drug therapy alone versus colonoscopic monitoring with treatment step-up. The POCER study.显示文摘 | Peter De Cruz Michael A. Kamm Amy L. Hamilton Kathryn J. Ritchie Soula Krejany Alexandra Gorelik Danny Liew Lani Prideaux Ian C. Lawrance Jane M. Andrews Peter A. Bampton Miles Sparrow Timothy H. Florin Peter R. Gibson Henry Debinski Richard B. Gearry Fin | 2013 | Gastroenterology2013，，5： | 1 |
| 2 | Mechanisms of asbestos-induced nitric oxide production by rat alveolar macrophages in inhalation and in vitro models 显示文摘 | Timothy RQ Kelly AB Miles PH | 1998 | Free Radic Biol Med1998，24，5： | 1 |
| 3 | Characterization and biological activity of flavonoids from ripe fruit of an anthracnose-resistant blueberry cultivar 显示文摘 | Timothy D Miles a | 2013 | Physiological and Molecular Plant Pathology2013，，2： | 1 |
| 4 | Endogenous bacterial endophthalmitis: A 17-year prospective series and review of 267 reported cases显示文摘 | Timothy L Jackson Susannah J Eykyn Elizabeth M Graham Miles R Stanford | 2003 | Survey of Ophthalmology2003，，4： | 1 |
| 5 | A statistical analysis of the detection performance of a broadband splitbeam passive so- nar显示文摘 | David A Miles David Kirk Timothy Clarke | 2006 | IEEE Journal of Oceanic Engineering2006，31，4： | 1 |
| 6 | Quantitative genetic analysis of biomass and wood chemistry of Populus under different nitrogen levels显示文摘 | Evandro Novaes Luis Osorio Derek R. Drost Brianna L. Miles Carolina R. D. Boaventura‐Novaes Catherine Benedict Christopher Dervinis Qibin Yu Robert Sykes Mark Davis Timothy A. Martin Gary F. Peter Matias Kirst | 2009 | New Phytologist2009，，4： | 1 |
| 7 | Endogenous bacterial endophthalmitis: A 17-year prospective series and review of 267 reported cases显示文摘 | Timothy L Jackson Susannah J Eykyn Elizabeth M Graham Miles R Stanford | 2003 | Survey of Ophthalmology2003，，4： | 1 |
| 8 | Uncovering genetic and metabolite markers associated with resistance against anthracnose fruit rot in northern highbush blueberry显示文摘Anthracnose fruit rot(AFR),caused by the fungal pathogen Colletotrichum fioriniae,is among the most destructive and widespread fruit disease of blueberry,impacting both yield and overall fruit quality.Blueberry cultivars have highly variable resistance against AFR.To date,this pathogen is largely controlled by applying various fungicides;thus,a more cost-effective and environmentally conscious solution for AFR is needed.Here we report three quantitative trait loci associated with AFR resistance in northern highbush blueberry(Vaccinium corymbosum).Candidate genes within these genomic regions are associated with the biosynthesis of flavonoids(e.g.anthocyanins)and resistance against pathogens.Furthermore,we examined gene expression changes in fruits following inoculation with Colletotrichum in a resistant cultivar,which revealed an enrichment of significantly differentially expressed genes associated with certain specialized metabolic pathways(e.g.flavonol biosynthesis)and pathogen resistance.Using non-targeted metabolite profiling,we identified a flavonol glycoside with properties consistent with a quercetin rhamnoside as a compound exhibiting significant abundance differences among the most resistant and susceptible individuals from the genetic mapping population.Further analysis revealed that this compound exhibits significant abundance differences among the most resistant and susceptible individuals when analyzed as two groups.However,individuals within each group displayed considerable overlapping variation in this compound,suggesting that its abundance may only be partially associated with resistance against C.fioriniae.These findings should serve as a powerful resource that will enable breeding programs to more easily develop new cultivars with superior resistance to AFR and as the basis of future research studies. | MacKenzie Jacobs Samantha Thompson Adrian E.Platts Melanie J.A.Body Alexys Kelsey Amanda Saad Patrick Abeli Scott J.Teresi Anthony Schilmiller Randolph Beaudry Mitchell J.Feldmann Steven J.Knapp Guo-qing Song Timothy Miles Patrick P.Edger | 2023 | Horticulture Research2023，10，10： | 0 |
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