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| 1 | Cardiac rehabilitation and exercise therapy in the elderly: Should we invest in the aged?显示文摘冠的心疾病(CHD ) 是世界范围的死亡的领先的原因并且在病人之中变得逐渐地流行 65 岁以上。老病人在为复杂并发症的更高的风险并且在一个心血管的事件以后加速物理 deconditioning,特别与他们的更年轻的对应物相比。最后几十年是到与 CHD 在病人之中在死亡,锻练能力,心理风险因素,发炎,和肥胖上表明了心脏的康复(CR ) 和锻练治疗的有益的效果的多重研究的厕所。不幸地,这个领域里的可得到的数据的重要部分与更年轻的病人相关。可行解释是更老的病人在为以病人开始并且延长到医生的多重原因的这些节目是非常未被充分代表的。在这篇文章,我们将考察 CR 节目的好处在之中老,以及一些妨碍他们的参予的障碍。 | Arthur R Menezes Carl J Lavie Richard V Milani Ross A Arena Timothy S Church | 2012 | Journal of Geriatric Cardiology2012，9，1： | 25 |
| 2 | Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells显示文摘外长的 dopaminergic 神经原(DA 神经原) 的移植是为治疗 Parkinson 的疾病(PD ) 的一条有希望的途径。然而,主要跌倒块是施主 DA 神经原的可靠来源的缺乏。这里,我们证明五 transcriptional 因素 Mash1, Ngn2, Sox2, Nurr1,和 Pitx3 的联合直接并且有效地装改编人成纤维细胞进 DA 像神经原的房间。为为 DA 神经原的各种各样的标记积极的染色的 reprogrammed 房间。他们也显示出典型 DA 举起和生产性质。而且,他们展出了 DA 神经原特定的 electrophysiological 侧面。最后,他们在一个老鼠 PD 模型提供了征兆的地势。因此,我们的直接 reprogrammed DA 像神经原的房间是为 PD 的房间代替治疗的有希望的来源。 | Xinjian Liu Fang Li Elizabeth A Stubblefield Barbara Blanchard Toni L Richards Gaynor A Larson Yujun He Qian Huang Aik-Choon Tan Dabing Zhang Timothy A Benke John R Sladek Nancy R Zahniser Chuan-Yuan Li | 2012 | Cell Research2012，22，2： | 14 |
| 3 | Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells显示文摘 | Saiyong Zhu Raiesh Ambasudhan Woong Sun Hyun Jung Kim Maria Talantova Xiaojing Wang Mingliang Zhang Yu Zhang Timothy Laurent James Parker Han-Seop Kim Jeffrey D Zaremba Sofiyan Saleem Sara Sanz-Blasco Eliezer Masliah Scott R McKercher Yee Sook Cho Stuart A Lipton Janghwan Kim Sheng Ding | 2014 | Cell Research2014，24，1： | 6 |
| 4 | CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice显示文摘 | Medina-Contreras Oscar Geem Duke Laur Oskar Williams Ifor R Lira Sergio A Nusrat Asma Parkos Charles A Denning Timothy L | 2011 | Journal of Clinical Investigation2011，，12： | 2 |
| 5 | 显示文摘 | Timothy A Becker Daryl R Kipke | 2002 | Journal of Biomedical Materials Research2002，61，4： | 1 |
| 6 | Product platform design:method and application 显示文摘 | Timothy W Simpson Jonathan R A Maier Farrokh Mistree | 2001 | Engineering Design2001，13，1： | 1 |
| 7 | Early metabolism changes during mdinitrobenzene neurotoxicity and the possible role of oxidative stress显示文摘 | Ignacio A R Timothy L Hugh K R | 1995 | Free Radical & Medicine1995，18，2： | 1 |
| 8 | Tillage effects on soil hydraulic properties in space and time:State of the science显示文摘 | Mark W S Timothy R G James C A | 2008 | Soil and Tillage Research2008，99，1： | 1 |
| 9 | An overview of the municipal waste incineration industry in Asia and the former Soviet Union显示文摘 | TIMOTHY R CROCKETT BODE M A | 1996 | Journal of Hazardous Material1996，47，： | 1 |
| 10 | Crystal and defect chemistry of rare earth cations in BaTiO3显示文摘 | YOED T TIMOTHY D D CLIVE A R | 2001 | J Electroceram2001，7，1： | 1 |
| 11 | The surgical treat ment of metastatic disease of the spine显示文摘 | Hatrick N C Lucas J D Timothy A R | 2000 | Radiother Oncol2000，56，3： | 1 |
| 12 | Ureteroscopy and holmium:YAG laser lithotripsy: an emerging definitive management strategy for symptomatic ureteral calculi in pregnancy显示文摘 | James D Watterson Andrew R Girvan Darren T Beiko Linda Nott Timothy A Wollin Hassan Razvi John D Denstedt | 2002 | Urology2002，，： | 1 |
| 13 | Personality and Performance at the Beginning of the New Millennium: What Do We Know and Where Do We Go Next显示文摘 | Barrick Murray R Mount Michael K etc Timothy A | 2001 | International Journal of Selection and Assessment2001，，12： | 1 |
| 14 | Potentiometric and fiberoptic sensors for pH based on an electropolymerized cobaltporphyrin显示文摘 | Timothy L B John R A Sylvia D | 1993 | Analytical Chemistry1993，65，15： | 1 |
| 15 | Lung Cancer Incidence Trends Among Men and Women - United States, 2005-2009显示文摘 | Henley S Jane Richards Thomas B Underwood J Michael Eheman Christie R Plescia Marcus McAfee Timothy A | 2014 | Morbidity and Mortality Weekly Report2014，，1： | 1 |
| 16 | Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptors显示文摘 | Timothy S McClintock Teresa M Landers Alexander A Gimelbrant Lynn Z Fuller Brian A Jackson Channa K Jayawickreme Michael R Lerner | 1997 | Molecular Brain Research1997，，2： | 1 |
| 17 | Leptin suppression of insulin secretion by the activation of ATP- sensitive K+ channels in pancreatic- Bcell 显示文摘 | Timothy J T J Kiefer R S HollerC A | 1997 | Diabetes1997，46，： | 1 |
| 18 | Architecture and stratigraphy of alluvial deposits,Morrison Formation(Upper Jurassic),Utah显示文摘 | Audun V K Edwin R S Timothy A C | 2008 | AAPG Bull2008，92，8： | 1 |
| 19 | Heme and iron metabolism: Role in cerebral hemorrhage显示文摘 | KENNETH R W FRANK R S TIMOTHY D A | 2003 | Cerebral Blood Flow & Metabolism2003，23，： | 1 |
| 20 | Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out -of- hospital: prospective observational study显示文摘 | Timothy H R Peter A C Devilliers S | 2003 | BMJ2003，326，21： | 1 |
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