4篇
您的检索式：作者名="Tingfeng Yao"
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| 1 | A vertically integrated eutrophication model and its application to a river-style reservoir-Fuchunjiang,China显示文摘Based on a 2-D hydrodynamic model,a vertically integrated eutrophication model was developed.The physical sub-model can be used for calculation of water density at different depths,and the water quality sub-model was used for calculation of algal growth.The cohesive and non-cohesive sediments were simulated separately with different methods.The light extinction coeffcient used in the underwater light regime sub-model was linearly related to the sum of sediment and phytoplankton biomass.Some components less important to the model were simplified to improve practicability and calculation effciency.Using field data from Fuchunjiang Reservoir,we calculated the sensitivity of ecological parameters included in this model and validated the model.The results of sensitivity analysis showed that the parameters strongly inffuenced the phytoplankton biomass,including phytoplankton maximum growth rate,respiration rate,non-predatory mortality rate,settling rate,zooplankton maximum filtration rate,specific extinction coeffcient for suspended solids and sediment oxygen demand rate.The model was calibrated by adjusting these parameters.Total chlorophyll a(chl-a) concentrations at different layers in the water column were reproduced very well by the model simulations.The simulated chl-a values were positively correlated to the measured values with Pearson correlation coeffcient of 0.92.The mean difference between measured and simulated chl-a concentrations was 12% of the measured chl-a concentration.Measured and simulated DO concentrations were also positively correlated(r = 0.74) and the mean difference was 4% of measured DO concentrations.The successful validation of model indicated that it would be very useful in water quality management and algal bloom prediction in Fuchunjiang Reservoir and a good tool for water quality regulation of other river-style reservoirs. | WU Tingfeng LUOLiancong QIN Boqiang CUI Guangbai YUZuoming YAO Zhiming | 2009 | Journal of Environmental Sciences2009，21，3： | 6 |
| 2 | Polluted lake restoration to promote sustainability in the Yangtze River Basin,China显示文摘China has sought to address water pollution in the last decade by introducing a wide range of laws and regulations(Table S1), which led to nationwide water quality improvement ^([1]). However, recent quantitative assessment of progress toward Sustainable Development Goals (SDGs) in China suggests that some SDGs underpinning goals for water pollution and biodiversity have not been met ^([2]). | Boqiang Qin Yunlin Zhang Jianming Deng Guangwei Zhu Jianguo Liu David P.Hamilton Hans W.Paerl Justin D.Brookes Tingfeng Wu Kai Peng Yizhou Yao Kan Ding Xiaoyan Ji | 2022 | National Science Review2022，9，1： | 4 |
| 3 | Temperature-sensitive polymeric nanogels encapsulating withβ-cyclodextrin and ICG complex for high-resolution deep-tissue ultrasound-switchable fluorescence imaging显示文摘One of the thorny problems currently impeding the applications of the fluorescence imaging technique is the poor spatial resolution in deep tissue.Ultrasound-switchable fluorescence(USF)imaging is a novel imaging tool that has recently been explored to possibly surmount the above-mentioned bottleneck.Herein,αβ-cyclodextrin/indocyanine green(ICG)complex-encapsulated poly(N-isopropylacrylamide)(PNIPAM)nanogel was synthesized and studied for ex vivo/in vivo deep tissue/high-resolution near infrared USF(NIR-USF)imaging.To be specific,our results revealed that the average diameter of the as-prepared nanogels was significantly decreased to-32 nm from-335 nm compared to the reported ICG-PNIPAM nanoparticles.Additionally,the excitation/emission characteristics of the ICG itself in present nanogels were almost completely retained,and the resultant nanogel exhibited high physiological stability and positive biocompatibility.In particular,the signal-to-noise ratio of the USF image for the PNIPAM/P-cyclodextrin/ICG nanogel(33.01±2.42 dB)was prominently higher than that of the ICG-PNIPAM nanoparticles(18.73±0.33 dB)in 1.5-cm-thick chicken breast tissues.The NIR-USF imaging in 3.5-cm-thick chicken breast tissues was achieved using this new probe.The e x v iv o NIR-USF imaging of the mouse liver was also successfully obtained.Animal experiments showed that the present nanogels were able to be effectively accumulated into U87 tumor-bearing mice via enhanced permeability and retention effects,and the high-resolution NIR-USF imaging of in v ivo tumor was efficiently acquired.The metabolism and in vivo biodistribution of the nanogels were evaluated.Overall,the results suggest that the current nanogel is a highly promising NIR-USF probe for deep tissue and high-resolution USF imaging. | Ruilin Liu Tingfeng Yao Yang Liu Shuai Yu Liqin Ren Yi Hong Kytai T.Nguyen Baohong Yuan | 2020 | Nano Research2020，13，4： | 1 |
| 4 | In vivo tumor ultrasound-switchable fluorescence imaging via intravenous injections of size-controlled thermosensitive nanoparticles显示文摘Near-infrared fluorescence imaging has emerged as a noninvasive,inexpensive,and ionizing-radiation-free monitoring tool for assessing tumor growth and treatment efficacy.In particular,ultrasound switchable fluorescence(USF)imaging has been explored with improved imaging sensitivity and spatial resolution in centimeter-deep tissues.This study achieved the size control of polymer-based and indocyanine green(ICG)encapsulated USF contrast agents,capable of accumulating in the tumor after intravenous injections.These nanoprobes varied in size from 58 to 321 nm.The bioimaging profiles demonstrated that the proposed nanoparticles can efficiently eliminate the background light from normal tissue and show a tumor-specific fluorescence enhancement in the BxPC-3 tumor-bearing mice models possibly via the enhanced permeability and retention effect.In vivo tumor USF imaging further demonstrated that these nanoprobes can effectively be switched“ON”with enhanced fluorescence in response to a focused ultrasound stimulation in the tumor microenvironment,contributing to the high-resolution USF images.Therefore,our findings suggest that ICG-encapsulated nanoparticles are good candidates for USF imaging of tumors in live animals,indicating their great potential in optical tumor imaging in deep tissue. | Liqin Ren Yang Liu Tingfeng Yao Kytai TNguyen Baohong Yuan | 2023 | Nano Research2023，16，1： | 0 |
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