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| 1 | 制干辣椒F_1代中色素含量的变异和遗传显示文摘研究了2个制干红辣椒F1代中色素含量的变异和遗传。以Gorogled6为试验母本,Negral和Kalocsai801分别为试验父本进行杂交。颜色的变异性在2个F1代表现出加性遗传,但也有一种例外。Gorogled6×Negral的F1代极显著地表明色素含量由加性值决定。第2个F1代即Gorogled6×Kalocsai801仅在1997年表明了与上面第1个F1代相似的结果。在本试验中,F1代色素含量的遗传用d/a比值(1.75~7.96)来表示,并显示出这种性状的超显性遗传。假设和实际的杂种优势作用极显著。 | Todorova V. Todorov Y. 徐乃林(译) 上官金虎(译) 庄灿然(译) | 2006 | 辣椒杂志2006，，2： | 6 |
| 2 | A Dominant Allele of Arabidopsis Pectin-Binding Wall-Associated Kinase Induces a Stress Response Suppressed by MPK6 but Not MPK3 Mutations显示文摘植物房间墙由纤维素纤维,灵活果胶聚合物,和一连串的分类糖类和蛋白质的一个矩阵组成。Arabidopsis 的像受体的联系墙的 Kinases (WAK ) 在墙中绑果胶,并且在开发期间并且为对病原体的回答为房间扩大两个都是必要的并且伤害。Mitogen 激活蛋白质 Kinases (MPK ) 在优核质形成在房间表面受体和 transcriptional 和酶规定之间的一个主要发信号连接,并且 Arabidopsis MPK6 和 MPK3 确实在到应力和病原体的开发和反应有重要角色。WAK2 的主导的等位基因要求 kinase 活动并且激活包括增加的 ROS 累积和涉及病原体抵抗的众多的基因的起来规定的压力回答,伤害,并且房间墙生物的续生说。这主导的等位基因要求功能的果胶绑定和 kinase 领域,显示它从事表明小径的 WAK。主要血浆膜生产 ROS 酶建筑群的空异种, rbohd/f 不压制导致 WAK2cTAP 的显型。mpk6,然而并非 mpk3,空等位基因能压制这个主导的 WAK2 变化,因此区分的 MPK3 和 MPK6 的效果,其活动以前被认为冗余。基因表示的果胶激活被消除在一 wak2 空,但是由导致的 WAK 主导的等位基因的 tempered 被提高基础压力相关的抄本层次。结果建议细胞墙的变化能在细胞的回答和帮助在导致一个大变化解释病原体和伤害的罐头怎么在生长上有一般效果的机制。 | Bruce D. Kohorn Susan L. Kohorn Tanya Todorova Gillian Baptiste Kevin Stansky Meghan McCullough | 2012 | Molecular Plant2012，5，4： | 4 |
| 3 | Lack of correlation between Treg quantification assays in inflammatory bowel disease patients显示文摘AIM:To compare the number of regulatory T-cells( Tregs) measured by flow cytometry with those obtained using a real-time quantitative PCR(q PCR) method in patients suffering from inflammatory bowel disease(IBD).METHODS:Tregs percentages obtained by both flow cytometry and q PCR methods in 35 adult IBD patients,18 out of them with Crohn′s disease(CD)and 17 with ulcerative colitis(UC)were compared to each other as well as to scores on two IBD activity questionnaires using the Harvey Bradshaw Index(HBI)for CD patients and the Simple Colitis Clinical Activity Index(SCCAI)for UC patients.The Treg percentages by flow cytometry were defined as CD4+CD25highCD127lowFOXP3+cells in peripheral blood mononuclear cells,whereas the Treg percentages by q PCR method were determined as FOXP3 promoter demethylation in genomic DNA.RESULTS:We found an average of 1.56%±0.78%Tregs by using flow cytometry,compared to 1.07%±0.53%Tregs by using q PCR in adult IBD patients.There were no significant correlations between either the percentages of Tregs measured by flow cytometry or q PCR and the HBI or SCCAI questionnaire scores in CD or UC patients,respectively.In addition,there was no correlation between Treg percentages measured by q PCR and those measured by flow cytometry(r=-0.06,P=0.73;Spearman Rho).These data suggest that,either Treg-related immune function or the clinical scores in these IBD patients did not accurately reflect actual disease activity.Until the cause(s)for these differences are more clearly defined,the resultssuggest caution in interpreting studies of Tregs in various inflammatory disorders.CONCLUSION:The two methods did not produce equivalent measures of the percentage of total Tregs in the IBD patients studied which is consistent with the conclusion that Tregs subtypes are not equally detected by these two assays. | Gunnar Brandhorst Darinka Todorova Petrova Sebastian Weigand Christoph Eberle Nicolas von Ahsen Jessica Schmitz Frank Christian Schultze Dirk Raddatz Michael Karaus Michael Oellerich Philip D Walson | 2015 | World Journal of Gastroenterology2015，21，11： | 2 |
| 4 | Mg 6 Ni formation in rapidly quenched amorphous Mg–Ni alloys显示文摘 | St. Todorova T. Spassov | 2008 | Journal of Alloys and Compounds2008，，1： | 2 |
| 5 | 中链脂肪酸及其α-单脂肪酸甘油酯的抗菌研究——单一作用和协同作用显示文摘对葡萄球菌属、棒状杆菌属、芽孢杆菌属、李斯特菌属和链球菌属的几种革兰氏阳性菌株进行中链脂肪酸及其α-单脂肪酸甘油酯的抗菌活性评价。α-单脂肪酸甘油酯比脂肪酸更具活性,其中α-单月桂酸甘油酯是最具活性的化合物。以化脓性链球菌为试验菌,观察作用效果。首先,阻断α-单月桂酸甘油酯甘油部分的羟基,得到一种具有显著抗菌活性的化合物(MIC,3.9μg/mL)。其次,考察α-单月桂酸甘油酯与α-单葵酸甘油酯两种成分混合物时,α-单月桂酸甘油酯与α-单葵酸甘油酯之间以及α-单月桂酸甘油酯与活性差的月桂酸之间的协同关系。其中一种成分优于另一种成分2倍的混合物比单独的某种成分更为活跃。此外,组成成分比例为1:1也是不利的。当α-单肉豆寇酸甘油酯的量等于或少于α-单月桂酸甘油酯时,α-单月桂酸甘油酯与单肉豆寇酸甘油酯对金黄色葡萄球菌209存在协同作用。 | Batovska D I Todorova I T Tsvetkova Ie | 2020 | 福建畜牧兽医2020，42，1： | 2 |
| 6 | Stable and unstable set for the Cauchy problem for a nonlinear wave equation with nonlinear damping and source terms显示文摘 | Todorova G | 1999 | J Math Ana Appl1999，239，1： | 2 |
| 7 | Novel MLH1 frameshift mutation in an extended hereditary nonpolyposis colorectal cancer family显示文摘AIM: To present novel frameshift mutation c.31delC [p.L11X] in the MLH1 gene identified in an extended Bulgarian hereditary non-polyposis colorectal cancer (HNPCC) family and to analyze the molecular and clinical findings within the pedigree concerning the proposal of adequate individual prophylactic strategy for all mutation carriers. METHODS: The pedigree of the family consists of 42 members in four generations. Search for mutations in the MLH1 and hMSH2 genes was performed in the pro-band. After PCR amplification of all exons including flanking intronic regions, amplicons were directly sequenced. RESULTS: The mutation was found in nine from the thirteen pedigree members who signed informed consent to participate in the study. In three adenocarcinomas, microsatellite instability and lack of the MLH1 protein expression were detected. The only one tubulovillous adenoma analyzed was microsatellite stable and the MLH1 protein showed an intact staining. CONCLUSION: The newly described mutation c.31delC is HNPCC causative. Besides the typical clinical features of the syndrome, we found a specific pathologic manifestation such as moderate to high differentiated adenocarcinomas of the colon. One of the mutation carriers developed a benign giant cell soft tissue tumor. The primary tumor localizations were frequently extracolonic and detailed yearly gastrointestinal and gynecological examinations have been proposed to the mutation carriers. We emphasize the importance of including the HNPCC genetic counseling and testing as well in the following surveillance of all patients at risk in the services covered by the health insurance in Bulgaria. | Tanya Kirilova Kadiyska Radka Petrova Kaneva Dimitar Georgiev Nedin Alexandrina Borisova Alexandrova Antonina Todorova Gegova Stoyan Ganchev Lalchev Tatyana Christova Vanio Ivanov Mitev Juergen Horst Nadja Bogdanova Ivo Marinov Kremensky | 2006 | World Journal of Gastroenterology2006，12，48： | 2 |
| 8 | Existence of a solution of the wave equation with nonlinear damping and source termd显示文摘 | Georgiev V Todorova G | 1994 | J Diff Equ1994，109，2： | 2 |
| 9 | Stable and unstable sets for the Cauchy problem for a nonlinear wave equation with nonlinear damping and source terms显示文摘 | TODOROVA G | 1999 | Math Anal Appl1999，239，： | 1 |
| 10 | Intraductal aspiration cytology and galactography for nipple discharge 显示文摘 | BAITCHEV G GORTCHEV G TODOROVA A | 2003 | Int Surg2003，88，2： | 1 |
| 11 | Weaning from long-term mechanical ventilation:a nonpulmonary weaning index显示文摘 | Todorova L Temelkov A | 2004 | J Clin Monit Comput2004，18，4： | 1 |
| 12 | Effect of dietary glutamine on tumor glutathionelevels and apoptosis-related proteins in DMBA-induced breast cancer of rats显示文摘 | Todorova VK Harms SA Kaufmann Y | 2004 | Breast Cancer ResTreat2004，88，3： | 1 |
| 13 | High mobility group B1 protein interacts with its receptor RAGE in tumorcells but not in normal tissues显示文摘 | Jordana Todorova Evdokia Pasheva | 2012 | Oncology Letters2012，，1： | 1 |
| 14 | Moderate diversity for better cluster ensembles显示文摘 | Hadjitodorov S T Kuncheva L I Todorova L P | 2005 | Information Fusion2005，7，3： | 1 |
| 15 | Stable and unstable sets for the Cauchy problem for a nonlinear wave equation with nonlinear damping and source terms显示文摘 | Todorova G | 1997 | J Math Anal Appl1997，，239： | 1 |
| 16 | Spatial patterns of biodiversity in the Black Sea: An assessment using benthic polychaetes 显示文摘 | Surugiu V Revkov N Todorova V | 2012 | Estuarine Coastal and Shelf Science2012，88，2： | 1 |
| 17 | Growth of single-crystal TiN/VN strained-lay superlattiees with extremely high mechanical hardness 显示文摘 | HELMERSSON U TODOROVA S BARNETT S A | 1987 | Journal of Applied Physics1987，62，2： | 1 |
| 18 | Optical and photocatalytic properties of composite TiO2/ZnO thin films显示文摘 | Giannakopoulou T Todorova N Giannouri M Yu J G Trapalis C | 2014 | Catalysis Today2014，230，： | 1 |
| 19 | Growth of single- crystal TiN/VN strained-layer superlattices with extremely high mechanical hardness 显示文摘 | Helmersson U Todorova S Barnett S A | 1987 | Journal of Applied Physics1987，62，2： | 1 |
| 20 | Improving quality and safety in the hospital: the link between organizational culture, burnout and quality of care显示文摘 | Montgomery A Todorova I Baban A | 2013 | Br J Health Psychol2013，18，3： | 1 |
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