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| 1 | Factors that influence outcome in non-invasive and invasive treatment in polycystic liver disease patients显示文摘AIM: To evaluate the factors that influence outcome of both non-invasive and invasive treatment of polycystic liver disease. METHODS: Analysis of clinical files of patients with complete follow-up from July 1986 to June 2006. RESULTS: Forty-one patients (male, 7; female, 34), 47.8 ± 11.9 years age, and 5.7 ± 6.7 years follow-up, were studied. Alkaline phosphatase (AP) elevation (15% of patients) was associated with the requirement of invasive treatment (IT, P = 0.005). IT rate was higher in symptomatic than non-symptomatic patients (65.4% vs 14.3%, P = 0.002), and in women taking hormonal replacement therapy (HRT) (P = 0.001). Cysts complications (CC) were more frequent (22%) in the symptomatic patients group (P = 0.023). Patients with body mass index (BMI) > 25 (59%) had a trend to complications after IT (P = 0.075). Abdominal pain was the most common symptom (56%) and indication for IT (78%). Nineteen patients (46%) required a first IT: 12 open fenestration (OF), 4 laparoscopic fenestration (LF) and 3 fenestration with hepatic resection (FHR). Three required a second IT, and one required a third procedure. Complications due to first IT were found in 32% (OF 16.7%, LF 25%, FHR 66.7%), and in thesecond IT in 66.7% (OF 100%). Follow-up mortality rate was 0. CONCLUSION: Presence of symptoms, elevated AP, and CC are associated with IT requirement. HRT is associated with presence of symptoms and IT requirement. Patients with BMI > 25 have a trend be susceptible to IT complications. The proportions of complications are higher in FHR and second IT groups. RS is more frequent after OF. | Josué Barahona-Garrido Jesús Camacho-Escobedo Eduardo Cerda-Contreras Jorge Hernández-Calleros Jesús K Yamamoto-Furusho Aldo Torre Misael Uribe | 2008 | World Journal of Gastroenterology2008，14，20： | 4 |
| 2 | 星形胶质细胞转录组分析指导的脑卒中靶标鉴定显示文摘星形胶质细胞支持正常的脑功能,但在卒中等病理条件下,星形胶质细胞反应性激活,其也可能参与神经退行性改变。反应性星形胶质细胞增生对机体有益或有害,与环境背景有关,但其分子基础仍未得到充分解释。借助RiboTag技术,我们在特异性地短暂性大脑中动脉闭塞(tMCAO)72h后的小鼠星形胶质细胞中,纯化翻译mRNA,构建卒中特异性星形胶质细胞翻译组数据库。我们发现,与对照组脑组织相比,tMCAO后的反应性星形胶质细胞显示与A2表型相关的转录物的富集,这与神经保护相关。星形胶质细胞也会上调大量潜在的神经毒性基因。我们共鉴定了1003个基因和38个转录因子的差异表达,其中Stat3,Sp1和Spi1变化最明显。为了进一步探索Stat3介导的通路对卒中发病机制的影响,我们选择星形胶质细胞特异性条件性缺失Stat3的小鼠制造tMCAO模型,发现这些小鼠的局灶性缺血卒中体积减少,且梗死72h后小鼠的运动结果改善。综上所述,本研究扩展了新兴的星形胶质细胞特异性靶向卒中治疗数据库,并肯定了星形胶质细胞是脑功能的关键保障细胞。 | Rakers C Schleif M Blank N Matu?ková H Ulas T H?ndler K Torres SV Schumacher T Tai K Schultze JL Jackson WS Petzold GC 聂昊 | 2019 | 神经损伤与功能重建2019，14，6： | 2 |
| 3 | Role of interleukin-1beta during pain and inflamma-tion显示文摘 | Ren K Torres R | | 0，，： | 1 |
| 4 | Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism显示文摘 | TORRES I O KUCHENBECKER K M NNADI C I | 2015 | Nat Commun2015，6，： | 1 |
| 5 | Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen 显示文摘 | Wang LH Torres R | 2002 | J Biol Chem2002，277，19： | 1 |
| 6 | Effects of corn replacement by sorghum in broiler diets on performanceand intestinal mucosa integrity显示文摘 | TORRES K A A PIZAURO J M SOARES C P | 2013 | Poultry Science2013，92，6： | 1 |
| 7 | Photoluminescence of Rhodamine 6G-doped amorphous TiO2 thin films grown by sol-gel 显示文摘 | PALOMINO M R TORRES K J LOZADA M R PORTILLO M O GARCIA R M ZELAYA A O | 2007 | Vacuum2007，81，1112： | 1 |
| 8 | Changes of procal-citonin level in multiple trauma patients 显示文摘 | Wojtaszek M Staskiewicz G Torres K | 2014 | Anaesthesiol Inten-sive Ther2014，46，2： | 1 |
| 9 | Stability of anthoeyanins and aseorbic acid of high pressure processed blood orange juice during storage显示文摘 | Torres B Tiwari B K Patras A | 2011 | Innovative Food Science and Emerging Technologies2011，12，： | 1 |
| 10 | Study of the effect of indoleamine 2,3-dioxygenase on murine mixed lymphocyte reactions and skin allograft rejection 显示文摘 | Sakurai K Zou JP Torres NI | 2002 | Transplant Proc2002，34，8： | 1 |
| 11 | Catalysts for production of lower olefins from synthesis gas: a review显示文摘 | Torres Galvis H M de Jong K P | 2013 | ACS Catalysis2013，3，9： | 1 |
| 12 | Influence of chloride, water, and organic solvents on the physical properties of i- onic liquids 显示文摘 | Seddon K R Stark A Torres M J | 2000 | Pure and Applied Chemistry2000，72，12： | 1 |
| 13 | 显示文摘 | Seddon K Stark A Torres M J | 2000 | Pure Appl Chem2000，72，12： | 1 |
| 14 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 15 | Assessment of the correlation between gender, age, body mass index and the severity of postopera- tive pain, nausea and vomiting in patients undergoing laparnscopic cholecysteetomy显示文摘 | Torres K Szuka]~a M Torres A | 2015 | Pol Merkur Lekarski2015，39，： | 1 |
| 16 | Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors显示文摘 | Lopez G Torres K Liu J | 2011 | Cancer Res2011，71，1： | 1 |
| 17 | Developmental and auxin-induced expression of the Arabidopsis prhs homeobex gene显示文摘 | Plesch G Stormann K Torres J T | 1997 | Plant J1997，12，： | 1 |
| 18 | Loading modeeffects on the fracture toughness and fatigue crack growth resistance of WC-Co cemented carbides 显示文摘 | TORRES Y SARIN V K ANGLADA M | 2005 | Scripta Materialia2005，52，11： | 1 |
| 19 | Stability of anthocyaninsand ascorbic acid of high pressure processed blood orange juice during storage显示文摘 | Torres B Tiwari B K Cullen A | | 0，，： | 1 |
| 20 | F-actin and myosin Ⅱ accelerate catecholamine release from chromaffin granules显示文摘 | Berberian K Torres A J Fang Q | 2009 | J Neurosci2009，29，3： | 1 |
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