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| 1 | Contemporary review of minimally invasive pancreaticoduodenectomy显示文摘AIM To assess the current literature describing various minimally invasive techniques for and to review short-term outcomes after minimally invasive pancreaticoduodenectomy(PD). METHODS PD remains the only potentially curative treatment for periampullary malignancies, including, most commonly, pancreatic adenocarcinoma. Minimally invasive approaches to this complex operation have begun to be increasingly reported in the literature and are purported by some to reduce the historically high morbidity of PD associated with the open technique. In this systematic review, we have searched the literature for high-quality publications describing minimally invasive techniques for PD-including laparoscopic, robotic, and laparoscopicassisted robotic approaches(hybrid approach). We have identified publications with the largest operative experiences from well-known centers of excellence for this complex procedure. We report primarily short term operative and perioperative results and some short term oncologic endpoints. RESULTS Minimal y invasive techniques include laparoscopic, robotic and hybrid approaches and each of these techniques has strong advocates. Consistently, across all minimally invasive modalities, these techniques are associated less intraoperative blood loss than traditional open PD(OPD), but in exchange for longer operating times. These techniques are relatively equivalent in terms of perioperative morbidity and short term oncologic outcomes. Importantly, pancreatic fistula rate appears to be comparable in most minimally invasive series compared to open technique. Impact of minimally invasive technique on length of stay is mixed compared to some traditional open series. A few series have suggestedthat initiation of and time to adjuvant therapy may be improved with minimally invasive techniques, however this assertion remains controversial. In terms of shortterms costs, minimally invasive PD is significantly higher than that of OPD. CONCLUSION Minimally invasive approaches to PD show great promise as a strategy to improve short-term outcomes in patients undergoing PD, but the best results remain isolated to high-volume centers of excellence. | Rui Dai Ryan S Turley Dan G Blazer | 2016 | World Journal of Gastrointestinal Surgery2016，8，12： | 5 |
| 2 | Hyaluronan and cell locomotion显示文摘 | Turley E A | 1992 | Cancer Metastasis Rev1992，11，1： | 2 |
| 3 | HA receptors: regulators of signaling to the cytoskeleton显示文摘 | Entwistle J Hall C L Turley E A | 1996 | J Cell Biochem1996，61，4： | 2 |
| 4 | The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages显示文摘 | Katherine L. Talks Helen Turley Kevin C. Gatter Patrick H. Maxwell Christopher W. Pugh Peter J. Ratcliffe Adrian L. Harris | 2000 | The American Journal of Pathology2000，，2： | 2 |
| 5 | Major Liver Resection in Elderly Patients: A Multi-Institutional Analysis显示文摘 | Srinevas K. Reddy Andrew S. Barbas Ryan S. Turley T. Clark Gamblin David A. Geller J. Wallis Marsh Allan Tsung Bryan M. Clary Sandhya Lagoo-Deenadayalan | 2011 | Journal of the American College of Surgeons2011，，5： | 2 |
| 6 | Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα显示文摘 | Daniel J Peet Stephen D Turley Wenzhen Ma Bethany A Janowski Jean-Marc A Lobaccaro Robert E Hammer David J Mangelsdorf | 1998 | Cell1998，，： | 2 |
| 7 | Generation of large numbers of immature and mature dendritic cells from rat bone marrow cultures显示文摘 | Talmor M Mirza A Turley S | 1998 | Eur J Immunol1998，28，3： | 1 |
| 8 | Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM显示文摘 | Yang B Zhang L Turley EA | 1993 | J Biol Chem1993，268，12： | 1 |
| 9 | The distribution and expression of the two isoforms of DNA topoisomerase Ⅱ in nomal and neoplastic human tissues显示文摘 | Turley H Comley M Houlbrook S | 1997 | Cancer1997，75，9： | 1 |
| 10 | Cholesterol metabolism in the brain 显示文摘 | Dietschy JM Turley SD | 2001 | Curr Opin Lipidol2001，12，2： | 1 |
| 11 | Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta 显示文摘 | Turley JM Funakoshi S Ruseetti FW | 1995 | Cell Growth Differ1995，6，6： | 1 |
| 12 | The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages显示文摘 | Katherine L. Talks Helen Turley Kevin C. Gatter Patrick H. Maxwell Christopher W. Pugh Peter J. Ratcliffe Adrian L. Harris | 2000 | The American Journal of Pathology2000，，2： | 1 |
| 13 | beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds 显示文摘 | Cheon SS Cheah AY Turley S | 2002 | Proc Natl Acad Sei USA2002，99，10： | 1 |
| 14 | Marine snow studies in the northeast Atlantic: distribution, composition and roles as a food source for migrating plankton显示文摘 | Lampitt R S Wishner K F Turley C M | 1993 | Marine Biology1993，116，4： | 1 |
| 15 | Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory maerophage populations显示文摘 | Hartnell A Steel J Turley H | 2001 | Blood2001，97，1： | 1 |
| 16 | Role of Niemann-Pick C1-Like 1 (NPC1L1)in intestinal sterol absorption 显示文摘 | Turley SD | 2008 | Lipidology2008，2，2： | 1 |
| 17 | The intestinal absorption of biliary and dietary cholesterol as a drug target for lowering the plasma choles- terol level显示文摘 | Turley SD Dietschy JM | 2003 | Prev Cardiol2003，6，1： | 1 |
| 18 | Transport of peptide-MHC class Ⅱ complexes in developing dendritic cells显示文摘 | Turley SJ Inaba K Garrett WS | 2000 | Science2000，288，5465： | 1 |
| 19 | The type Ⅲ transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer显示文摘 | Turley R S Finger E C Hempel N | 2007 | Cancer Res2007，67，3： | 1 |
| 20 | Association be-tween personal health record enrollment and patient loyal-ty显示文摘 | Turley M Garrido T Lowenthal A | 2012 | Am J Manag Care2012，18，7： | 1 |
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