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| 1 | 胆道肿瘤临床实践指南(英文第三版)显示文摘日本肝胆胰外科学会(JSHBPS)于2007年出版第一版胆道肿瘤(胆管癌、胆囊癌及壶腹癌)临床实践指南,于2014年更新第二版,2021年英文第三版胆道肿瘤临床实践指南围绕6个主题提出若干临床问题,基于相关循证医学证据并组织专家讨论后,最终确定推荐意见、推荐强度以及推荐说明。根据证据推荐分级的评估、制订与评价(GRADE)系统,推荐强度被分为1级(强)或者2级(弱)。英文第三版胆道肿瘤临床实践指南中提出的31个临床问题涵盖:(1)预防性治疗;(2)诊断;(3)胆道引流;(4)外科治疗;(5)化疗;(6)放疗。31个临床问题中,14个问题给予推荐强度为强的推荐意见,14个问题给予推荐强度为弱的推荐意见,剩余的3个问题未给予推荐意见。每条推荐意见都进行推荐强度说明。最新版指南基于循证医学证据,为临床提供了重要建议。未来与癌症登记数据库协作将是评估指南和建立新证据的关键。 | Masato Nagino Satoshi Hirano Hideyuki Yoshitomi Taku Aoki Katsuhiko Uesaka Michiaki Unno Tomoki Ebata Masaru Konishi Keiji Sano Kazuaki Shimada Hiroaki Shimizu Ryota Higuchi Toshifumi Wakai Hiroyuki Isayama Takuji Okusaka Toshio Tsuyuguchi Yoshiki Hirooka Junji Furuse Hiroyuki Maguchi Kojiro Suzuki Hideya Yamazaki Hiroshi Kijima Akio Yanagisawa Masahiro Yoshida Yukihiro Yokoyama Takashi Mizuno Itaru Endo 杨翼飞(译) 仇毓东(译) 赵梦珂(译) 伏旭(译) 蔡正华(译) 毛凉(审校) | 2021 | 中华消化外科杂志2021，20，4： | 7 |
| 2 | Aggressive preoperative management and extended surgery for hilar cholangiocarcinoma: Nagoya experience显示文摘 | Yuji Nimura Junichi Kamiya Satoshi Kondo Masato Nagino Katsuhiko Uesaka Koji Oda Tsuyoshi Sano Hideo Yamamoto Naokazu Hayakawa | 2000 | Journal of Hepato - Biliary - Pancreatic Surgery2000，，2： | 6 |
| 3 | Complications of Hepatectomy for Hilar Cholangiocarcinoma显示文摘 | Masato Nagino Junichi Kamiya Katsuhiko Uesaka Tsuyoshi Sano Hideo Yamamoto Naokazu Hayakawa Michio Kanai Yuji Nimura | 2001 | World Journal of Surgery2001，，10： | 2 |
| 4 | Twenty four-week peginterferon plus ribavirin after interferon-β induction for genotype 1b chronic hepatitis C显示文摘AIM:To investigate the possibility of shortening the duration of peginterferon(Peg-IFN)plus ribavirin(RBV) combination therapy by incorporating interferon-β (IFN-β)induction therapy. METHODS:A one treatment arm,cohort prospective study was conducted on seventy one patients.The patients were Japanese adults with genotype 1b chronic hepatitis C,HCV-RNA levels of≥5.0 Log IU/mL or 100 KIU/mL,and platelet counts of≥90 000/μL.The treatment regimen consisted of a 2 wk course of twicedaily administration of IFN-βfollowed by 24 wk PegIFN plus RBV combination therapy.We prolonged the duration of the Peg-IFN plus RBV therapy to 48 wk if the patient requested it. RESULTS:The patients,including 44%males,were characterized by an median age of 63 years(range: 32-78 years),an median platelet count of 13.9(range: 9.1-30.6)×10 4 /μL,62%IFN-na?ve,and median HCV- RNA of 6.1(range:5.1-7.2)Log IU/mL.The sustained virologic response(SVR)rates were 34%(Peg-IFN:1-24 wk,n=61,95%confidence interval(CI): 24%-47%)and 55%(Peg-IFN:20-24 wk,n=31,95% CI:38%-71%,P<0.001;vs Peg-IFN:1-19 wk).TheSVR rate when the administration was discontinued early was 13%(Peg-IFN:1-19 wk,n=30,95%CI: 5%-30%),and that when the administration was prolonged was 50%(Peg-IFN:25-48 wk,n=10,95% CI:24%-76%,P<0.05;vs Peg-IFN:1-19 wk).In the patients who received 20-24 wk of Peg-IFN plus RBV,only the higher platelet count(≥130 000/μL) was significantly correlated with the SVR(odds ratio: 11.680,95%CI:2.3064-79.474,P=0.0024).In 45% (14/31)of the patients with a higher platelet count (≥130000/μL)before therapy,the HCV-RNA level decreased to below 3.3 Log IU/mL at the completion of IFN-β,and their SVR rate was 93%(13/14)after 20-24 wk administration of Peg-IFN plus RBV. CONCLUSION:These results suggest the possibilities of shortening the duration of Peg-IFN plus RBV combination therapy by actively reducing HCV-RNA levels using the IFN-βinduction regimen. | Hiroaki Okushin Kazuhiko Morii Koichi Uesaka Shiro Yuasa | 2010 | World Journal of Hepatology2010，2，6： | 2 |
| 5 | Hepatectomy With Portal Vein Resection for Hilar Cholangiocarcinoma: Audit of 52 Consecutive Cases显示文摘 | Tomoki Ebata Masato Nagino Junichi Kamiya Katsuhiko Uesaka Tetsuro Nagasaka Yuji Nimura | 2003 | Annals of Surgery2003，，5： | 2 |
| 6 | Short-term intravenous interferon therapy for chronic hepatitis B显示文摘AIM:To investigate the therapeutic efficacy of short- term, multiple daily dosing of intravenous interferon (IFN) in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B. METHODS:IFN-β was intravenously administered at a total dose of 102 million international units (MIU) over a period of 28 d in 26 patients positive for HBeAg and HBV-DNA. IFN-beta was administered at doses of 2 MIU and 1 MIU on d 1, 3 MIU twice daily from d 2 to d 7, and 1 MIU thrice daily from d 8 to d 28. Patients were followed up for 24 wk after the end of treatment. RESULTS:Six months after the end of the treatment, loss of HBV-DNA occurred in 13 (50.0%) of the 26 patients, loss of HBeAg in 9 (34.6%), development of anti-HBe in 10 (38.5%), HBeAg seroconversion in 8 (30.8%), and normalization of alanine aminotransferase (ALT) levels in 11 (42.0%). CONCLUSION:This 4-wk long IFN-β therapy, which was much shorter than conventional therapy lasting 12 wk or even more than 1 year, produced therapeutic effects similar to those achieved by IFN-α or pegylated- IFN-α (peg-IFN). Fewer adverse effects, greater efficacy, and a shorter treatment period led to an improvement in patients’ quality of life. IFN-β is administered intravenously, whereas IFN-α is administered intramuscularly or subcutaneously. Because both interferons are known to bind to an identical receptor and exert antiviral effects through intracellular signal transduction, the excellent results of IFN-β found in this study may be attributed to the multiple doses allowed by the intravenous route. | Hiroaki Okushin Toru Ohnishi Kazuhiko Morii Koichi Uesaka Shiro Yuasa | 2008 | World Journal of Gastroenterology2008，14，19： | 2 |
| 7 | High fat diet enhances colonic cell proliferation and carcinogenesis in rats by elevating serum leptin显示文摘 | Liu Z Uesaka T Watanabe H | 2001 | Int J Oncol2001，19，5： | 1 |
| 8 | ZK7, a novel zinc finger gene is indumed by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic calls 显示文摘 | Kummoto K Uesaka T Kimura A | 2000 | Cancer Res2000，60，2： | 1 |
| 9 | Eddy-current testing by flexible microloop magnetic sensor array显示文摘 | Uesaka M Hakuta K Miya K | 1998 | IEEE Transactions on Magnetics1998，34，4： | 1 |
| 10 | Properties of high-purity polycrystalline cBN 显示文摘 | Sumiya Hitoshi Uesaka Shinya | 2000 | New Diamond and Frontier Carbon Technology2000，10，1： | 1 |
| 11 | Modelling paper structure and paper-press interactions显示文摘 | Provatas N Uesaka T | 2003 | Journal of Pulp and Paper Science2003，29，10： | 1 |
| 12 | Margin status, recurrence pattern, and prognosis after resection of pancreatic cancer 显示文摘 | Sugiura T Uesaka K Mihara K | 2013 | Surgery2013，154，5： | 1 |
| 13 | GDNF signaling levels con- trol migration and neuronal differentiation of enteric ganglion precur- sors显示文摘 | Uesaka T Nagashimada M Enomoto H | 2013 | J Neurosci2013，33，16： | 1 |
| 14 | Higll fat diet enhances colonic cell proliferation and carcinogenesis in rat by elevating serum leptin 显示文摘 | Liu Z Uesaka T Watanabe H | 2001 | Int J Onool2001，19，5： | 1 |
| 15 | Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system显示文摘 | Nishiyama C Uesaka T Manabe T | 2012 | Nat Neurosci2012，15，9： | 1 |
| 16 | Mechanical properties of high purity polycrystalline CBN synthesized by direct conversion sintering method 显示文摘 | SUMIYA H UESAKA S SATOH S | 2000 | Journal of Materials Science2000，35，5： | 1 |
| 17 | 日本肝胆胰外科协会胆道恶性肿瘤临床管理实践指南2019版英文第三版(第二部分)显示文摘日本肝胆胰外科协会2021年第三版日文、英文版日本胆管恶性肿瘤临床实践管理指南对内容意见进行了更新.提出了共涉及疾病的预防、诊断、胆管引流、外科手术、化疗、放疗六个临床主题领域31项核心问题,介绍日本胆道恶性肿瘤临床管理及治疗经验以飨读者.本期将继续介绍该指南关于胆道恶性肿瘤的外科手术、化疗、放疗处理方面的内容. | NAGINO M HIRANO S YOSHITOMI H Aoki T Uesaka K Unno M 薛鸿(摘译) 崔笑(摘译) 耿小平(审校) | 2021 | 肝胆外科杂志2021，29，5： | 1 |
| 18 | Studies on aliphatie portion of coal organic materials based on ruthenium ion catalyzed oxidation显示文摘 | MURATA S UESAKA K | 1994 | Energy& Fuels1994，8，6： | 1 |
| 19 | Discrepancy between the percentage of hypochromic erythrocytes and the reticulocyte hemoglobin content in hemodialysis patients with recombinant human erythropoietin therapy 显示文摘 | Asanuma M Taguchi C Uesaka H | 2005 | Lab Hematol2005，11，2： | 1 |
| 20 | Liver-specific contrast agent-enhanced magnetic resonance and 18F-fluorodeoxyglucose positron emission tomography findings of hepatocellular adenoma: report of a case显示文摘 | Tatsuaki Sumiyoshi Michihisa Moriguchi Hideyuki Kanemoto Kouiku Asakura Keiko Sasaki Teiichi Sugiura Takashi Mizuno Katsuhiko Uesaka | 2012 | Surgery Today2012，，2： | 1 |
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