|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 高效薄层色谱在美国草药典中的应用显示文摘扼要介绍了美国草药使用的历史及现状以及美国草药典委员会成立的背景 ,还重点介绍了美国草药典选择平面色谱 (即现代高效薄层色谱 )在控制草药质量方面应用的理由及实例。 | ROY Upton 张林海 孙亦峰 | 2001 | 中药新药与临床药理2001，12，3： | 12 |
| 2 | 低水平电离辐射致癌效应剂量响应关系的评论性再评估显示文摘数十年来 ,为了辐射防护目的 ,通常假定辐射诱发癌的总危险是随着剂量呈线性无阈函数增加。现有的资料并不排除有阈存在 ,然而 ,剂量响应关系的变化是依赖于所论及的癌症类型 ,剂量 ,剂量率 ,以及辐射的 L ET,受照个体的年龄、性别和生理状态 ,以及其他因素 ,其中包括在低剂量条件下的适应性响应和旁观者效应的潜在影响。所以 ,根据不断发展的科学知识 ,下列机构定期对低水平辐射的剂量响应关系进行再评估 ,这些机构是 :美国国家辐射防护与测量委员会 ( NCRP) ,国际放射防护委员会 ( ICRP) ,联合国原子辐射效应科学委员会 ( UN SCEAR) ,美国国家科学院 ( USN AS)以及其他机构。近来这些评论普遍发现的重要证据认为 ,作为癌症前体的损伤 (例如突变和染色体畸变 ) ,以及某些类型癌症 ,其发生率在低剂量范围内将随着剂量线性增加。在此基础上 ,可以得出以下结论 :对于低水平辐射的致癌效应 ,尽管不排除有其他剂量响应关系 。 | Arthur C Upton 陈兴安 | 2003 | 辐射防护通讯2003，23，2： | 6 |
| 3 | The association between frailty and vascular dementia显示文摘 | Daniel KY Chan Vivek Srinivasan Ciaran Upton Xueli Chen Roman Romero-Ortuno | 2015 | 中华老年医学杂志2015，34，12： | 4 |
| 4 | Orientational Domains at Room Temperature in La_(0.33) Ca_(0.67) MnO_3 Perovskite显示文摘Orientational domains at room temperature in orthorhombic perovskite La 0.33 Ca 0.67 MnO 3 were studied by group theory and observed systematically using transmission electron microscopy. There are six orientational variants ( A, A’, B,B’, C and C’ ) in orthorhombic perovskite La 0.33 Ca 0.67 MnO 3. Their orthorhombic b O directions are parallel to the a P, b P and c P directions of the cubic prototypic perovskite, respectively. In each case there are two orientational variants (e.g., A and A’ ) with their a O and c O axes interchanged. Among the possible 15 boundaries between these 6 variants there are only two types of domain boundaries: (1) m<100> boundaries C’/C, A’/A, and B’/B. (2) m<110> boundaryies C’/A, C’/A’, C’/B, C’/B’, C/A, C/A’, C/B, C/B’, B’/A, B’/A’, B/A, and B/A’ . | WANG Ren hui 1,2) ,GUI Jia nian 1,2) ,ZHU Yi mei 2) , A. R. Moodenbaugh 2) 1. Department of Physics, Wuhan University, Wuhan 430072, China 2. Department of Applied Science, Brookhaven National Laboratory, Upton, NY 11973 | 1999 | Wuhan University Journal of Natural Sciences1999，4，4： | 3 |
| 5 | Translational pain research: Evaluating analgesic effect in experimental visceral pain models显示文摘Deep visceral pain is frequent and presents major challenges in pain management, since its pathophysiology is still poorly understood. One way to optimize treatment of visceral pain is to improve knowledge of the mechanisms behind the pain and the mode of action of analgesic substances. This can be achieved through stand-ardized experimental human pain models. Experimental pain models in healthy volunteers are advantageous for evaluation of analgesic action, as this is often diff icult to assess in the clinic because of confounding factors such as sedation, nausea and general malaise. These pain models facilitate minimizing the gap between knowledge gained in animal and human clinical studies. Combining experimental pain studies and pharmacokinetic stud- ies can improve understanding of the pharmacokinetic-pharmacodynamic relationship of analgesics and, thus, provide valuable insight into optimal clinical treatment of visceral pain. To improve treatment of visceral pain, it is important to study the underlying mechanisms of pain and the action of analgesics used for its treatment. An experimental pain model activates different modalities and can be used to investigate the mechanism of action of different analgesics in detail. In combination with pharmacokinetic studies and objective assessment such as electroencephalography, new information re-garding a given drug substance and its effects can be obtained. Results from experimental human visceral pain research can bridge the gap in knowledge between animal studies and clinical condition in patients suffering from visceral pain, and thus constitute the missing link in translational pain research. | Anne Estrup Olesen Trine Andresen Lona Louring Christrup Richard N Upton | 2009 | World Journal of Gastroenterology2009，15，2： | 3 |
| 6 | Epidemiology of Cryptosporidium : transmission, detection and identification显示文摘 | Ronald Fayer Una Morgan Steve J Upton | 2000 | International Journal for Parasitology2000，，12： | 3 |
| 7 | Shikonin reduces TGF-β1-induced collagen production and contractionin hypertrophic scar-derived human skin fibroblasts显示文摘 | Chen Fan Ying Dong Yan Xie Yonghua Su Xufang Zhang David Leavesley Zee Upton | 2015 | International Journal of Molecular Medicine2015，，4： | 2 |
| 8 | The small footprint wastewater treatment process 显示文摘 | Stephenson Tom Allan Man Upton John | 1993 | Chemistry & Industry1993，19，： | 2 |
| 9 | Epidemiology of Cryptosporidium : transmission, detection and identification显示文摘 | Ronald Fayer Una Morgan Steve J Upton | 2000 | International Journal for Parasitology2000，，12： | 2 |
| 10 | Insulin-like growth factors in poultry 显示文摘 | MCMURTYR J P FRANCIS G L UPTON Z | 1997 | Domest Anim Endocrinol1997，14，4： | 1 |
| 11 | Understanding direct mail letters as a genre显示文摘 | Upton T | 2002 | International Journal of Corpus Linguistics2002，7，1： | 1 |
| 12 | Diffuse venous malformations of the upper limb:morphologie characterization by MRI and venography显示文摘 | Upton J Burrows PE | 2001 | Pediatr Radiol2001，31，7： | 1 |
| 13 | Leasing, buying and the cost of capital services显示文摘 | Moller M H Upton C W | 1976 | Journal of Finance1976，31，： | 1 |
| 14 | Age of some Gardar intrusive com plexes, South Greenland 显示文摘 | Breemen O V Upton B G J | 1972 | Geological Society of America Bulletin1972，83，： | 1 |
| 15 | Prenatal diagnosis of vascular anomalies显示文摘 | Marler JJ Fishman SJ Upton J | 2002 | J Pediatr Surg2002，37，： | 1 |
| 16 | Tissue-engineered growth of bone and cartilage 显示文摘 | Vacanti CA Kim W Upton J | 1993 | Transplant Proc1993，25，1： | 1 |
| 17 | Increased matrix metalloproteinase-9 (MMP-9) activity observed in chronic wound fluid is related to the clinical severity of the ulcer显示文摘 | Rayment EA Upton Z Shooter GK | 2008 | Br J Dermatol2008，158，： | 1 |
| 18 | Histopathological review of salivary glandtumors in childhood 显示文摘 | Lack EE Upton MP | 1988 | Arch Otolaryngol Head Neck Surg1988，114，8： | 1 |
| 19 | Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy显示文摘 | Mina John Corey B. Moore Ian R. James David Nolan Richard P. Upton Elizabeth J. McKinnon Simon A. Mallal | 2001 | AIDS2001，，6： | 1 |
| 20 | Depressive symptoms post hip fracture in older adults are associated with phenotypic and functional alterations in T cells 显示文摘 | Niharika Arora Dugga Jane Upton Anna C Phillips | 2014 | Peter Immunity Ageing2014，11，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员