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| 1 | Diagnostic accuracy of enhanced liver fibrosis test to assess liver fibrosis in patients with chronic hepatitis C显示文摘BACKGROUND:The prognosis and clinical management of patients with chronic liver diseases are closely related to the severity of liver fibrosis.Liver biopsy is considered the gold standard for the staging of liver fibrosis.However,it is an invasive test sometimes related to complications.This study aimed to assess the diagnostic value of enhanced liver fibrosis(ELF) test to predict liver fibrosis in patients with chronic hepatitis C.METHODS:This study included 162 patients with liver disease and 67 healthy controls.Hyaluronic acid,tissue inhibitor of matrix metalloproteinase type 1,and amino-terminal propeptide type III procollagen were measured by enzymelinked immunosorbent assay with the ELF test ADVIA Centaur(Siemens Healthcare Diagnostics Inc.).Fibrosis stage was determined using the Metavir scoring system.RESULTS:In our study,for the diagnosis of significant fibrosis(Metavir F≥2) a cut-off value >7.72 provides a sensitivity of 93.0% and a specificity of 83.0%.The areas under the receiver operator characteristic curve,sensitivity,specificity,and positive and negative predictive values were 0.94,93.3%,81.0%,93.3%,and 81.0%,respectively(P<0.001).For the diagnosis of cirrhosis(Metavir F=4) a cut-off value >9.3 provides a sensitivity of 93.0% and a specificity of 86.0%.The areas under the receiver operator characteristic curve,sensitivity,specificity,and positive and negative predictive values were 0.94,79.1%,90.8%,75.6%,and 92.3%,respectively(P<0.001).CONCLUSIONS:The ELF test is a promising non-invasive method for assessing liver fibrosis in patients with chronic hepatitis C.It is effective in the diagnosis of both fibrosis and cirrhosis. | Roberto Catanzaro Michele Milazzo Silvia Arona Chiara Sapienza Dario Vasta Domenico Arcoria Francesco Marotta | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 3 |
| 2 | Study on Corrosion Inhibition From Aspect of Quantum Chemistry显示文摘 | Vasta J Eliasek | 1997 | Corros Sci1997，，1： | 1 |
| 3 | Significance of the effective remnant liver volume in major hepatectomies 显示文摘 | Gruttadauria S Vasta F Minervini MI | 2005 | Ann Surg2005，71，3： | 1 |
| 4 | Thermal conductivity measurement of a PCM based storage system containing carbon fibers 显示文摘 | FRUSTERI F LEONARDI V VASTA S | 2005 | Applied Thermal Engineering2005，25，1112： | 1 |
| 5 | Antioxidant status, colour stability and myoglobin resistance to oxidation of longissimus dorsi muscle from Iambs fed a tannin-containing diet显示文摘 | Luciano G Vasta V Monahan FJ | 2011 | Food Chemistry2011，124，： | 1 |
| 6 | Purification and properties of salmonella typhmuriumacetolactate synthase isozyme Ⅱ from Esehierchia coli HB101/pUD9显示文摘 | Schloss J Van Dyk D Vasta J | 1985 | Biochemistry1985，，24： | 1 |
| 7 | Improvement in hepatic parenchyma transaction for living related liver donor显示文摘 | CRUTTA DAURIA S MANDALA L VASTA F | 2005 | Trannsplant Proe2005，37，6： | 1 |
| 8 | Roles of galeetins in infection显示文摘 | Vasta GR | 2009 | Nat Rev Micnbiol2009，7，6： | 1 |
| 9 | Roles of galectins in infection显示文摘 | Vasta GR | 2009 | Nat Rev Microbiol2009，7，6： | 1 |
| 10 | Roles of galectins in infection显示文摘 | Vasta GR | 2009 | Nat Rev Microbiol2009，7，6： | 1 |
| 11 | Galectins as pattern recognition receptors: structure, function, and evolution显示文摘 | Vasta GR | 2012 | Adv Exp Med Biol2012，946，： | 1 |
| 12 | Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival显示文摘 | M. T. Elola C. Wolfenstein-Todel M. F. Troncoso G. R. Vasta G. A. Rabinovich | 2007 | Cellular and Molecular Life Sciences2007，，13： | 1 |
| 13 | Effects of Ce3+ codoping and annealing on phase transformation and luminescence of Eu3+-doped YPO4 nanorods:D2-solvent effect显示文摘 | LUWANG N NINGTHOUJAM S JAGANNATH SRIVASTAVA S K VASTA R K | | 0，，08： | 1 |
| 14 | Thermal conductivity measurement of a PCM based storage system containing carbon fi-tmrs显示文摘 | Frusteri F Leonardi V Vasta S | 2005 | Applied Thermal Engineering2005，25，： | 1 |
| 15 | Targeted exome sequencing for mitochondrial disorders reveals high genetic heterogeneity 显示文摘 | DaRe JT Vasta V Penn J | 2013 | BMC Med Genet2013，14，： | 1 |
| 16 | A method for the proba- bilistic analysis of nonlinear systems 显示文摘 | PAOLA M D RICCIARDI G VASTA M | 1995 | Probabilistic Engineering Mechanics1995，10，1： | 1 |
| 17 | Markov modeling and stochastic Identification for nonlinear ship rolling in random waves显示文摘 | Roberts J B Vasta M | 2000 | Phil Trans R Soc Lond2000，，2000： | 1 |
| 18 | Significance of the effective remnant liver volume in major hepatectomies显示文摘 | Gruttadauria S Vasta F Minervini MI | 2005 | Am Surg2005，71，3： | 1 |
| 19 | Regional cerebral blood flow during hypoxia-ischemia in immature rats显示文摘 | Vannucci RC Lyons DT Vasta F | 1988 | Stroke1988，19，： | 1 |
| 20 | Glutaminc transport and enzymatic activities involved in glutaminolysisin human platelets 显示文摘 | Vasta V Meaeci E Famararo M | 1995 | Acta Biophysics1995，1243，： | 1 |
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